About PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE
PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE is primarily used to treat the common cold and allergy symptoms like sneezing, watery eyes or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by 'rhinovirus'. The virus spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.
PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE contains Paracetamol, Phenylephrine hydrochloride, Chlorpheniramine maleate, and Caffeine. Paracetamol inhibits the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Phenylephrine hydrochloride helps shrink the blood vessels in the nasal passage, thereby reducing the stuffy nose. Chlorpheniramine maleate blocks the action of histamine, a substance responsible for causing allergic reactions. Caffeine acts as a stimulant and increases alertness.
PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE can be taken with or without food or as directed by the physician. Your doctor will recommend how often you need to take PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE based on your medical condition. In some cases, PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE may cause common side effects such as drowsiness, sleepiness, nausea, fatigue, difficulty sleeping, and headache. Most 0f these side effects do not require medical attention and will resolve gradually over time. However, consult your doctor if the side effects persist or worsen.
Do not consume PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE if you are allergic or hypersensitive to any of the components. Consult your doctor if you are pregnant, planning for pregnancy, or breastfeeding. Inform your doctor if you have hypertension (high blood pressure), liver or kidney disease, or coronary artery disease (heart disease). PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE may cause sleepiness, so do not drive or operate heavy machinery unless you are alert. Consumption of alcohol should be avoided as it may lead to excessive sleepiness.
Uses of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE
Common cold, Allergies
Medicinal Benefits
PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE is composed of four medicines, namely: Paracetamol (mild analgesic and antipyretic), Phenylephrine hydrochloride (decongestant), Chlorpheniramine maleate (antihistamine), and Caffeine (a stimulant). Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Phenylephrine hydrochloride helps shrink the blood vessels in the nasal passage, thereby reducing the stuffy nose. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Caffeine acts as a stimulant, which decreases sleepiness and increases alertness. Thereby, PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE helps treat the common cold and allergy symptoms like sneezing, watery eyes, or itchy/watery nose and throat.
Directions for Use
Storage
Side Effects of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE
- Drowsiness
- Nervousness
- Headache
- Dizziness
- Insomnia
- Dryness in mouth
- Constipation
- Nausea
- Vomiting
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE. If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE. Do not take PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days.
Drug Interactions
Drug-Drug Interactions: PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, imipramine, amitriptyline), anticonvulsants (clonazepam), antianxiety drug (alprazolam), cough suppressants (dextromethorphan), bronchodilator (albuterol), melatonin receptor agonist (ramelteon), and pain killers (ibuprofen).
Drug-Food Interactions: Avoid intake of caffeine-containing foods (like coffee) and alcoholic beverages as they may cause increased drowsiness, dizziness, and difficulty concentrating.
Drug-Disease Interactions: If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, Raynaud's phenomenon (decreased blood flow to the fingers), enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are recommended not to consume alcohol along with PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE to avoid excessive drowsiness and sleepiness.
Pregnancy
cautionThe safety of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE in pregnant women is unknown. Therefore, please consult a doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionThe safety of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE in breastfeeding women is unknown. Therefore, please consult a doctor. Your doctor will prescribe only if the benefits outweigh the risks.
Driving
cautionPARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE may cause drowsiness, so please do not drive or operate any machinery unless you are alert.
Liver
cautionTake PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionPlease consult your doctor if you have any concerns regarding the usage of PARACETAMOL+PHENYLEPHRINE HYDROCHLORIDE+CHLORPHENIRAMINE MALEATE+CAFFEINE in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.
Children
cautionLimited information is available. Please consult your doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- To reduce the risk of spreading a cold: Wash your hands with soap and water regularly to prevent the spread of germs.
- Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
- Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
- Gargle with salt water for relief from sore throat.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by 'rhinoviruses', affecting the nose and throat (upper respiratory tract). Children younger than six years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, stuffy, or runny nose.
Allergy: It occurs when allergy-causing agents (allergens) attack and invade the body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, throat, and watery eyes. Allergy generally occurs due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.
