TENOFOVIR ALAFENAMIDE belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.
TENOFOVIR ALAFENAMIDE contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.
Take TENOFOVIR ALAFENAMIDE as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of TENOFOVIR ALAFENAMIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
You should not take TENOFOVIR ALAFENAMIDE if you are allergic to TENOFOVIR ALAFENAMIDE or any other contents present in it. Avoid taking TENOFOVIR ALAFENAMIDE if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using TENOFOVIR ALAFENAMIDE as it may cause dizziness, affecting your ability to drive or use machines. Should not use TENOFOVIR ALAFENAMIDE for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.
Chronic hepatitis B
TENOFOVIR ALAFENAMIDE ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.
You should not take TENOFOVIR ALAFENAMIDE if you are allergic to TENOFOVIR ALAFENAMIDE or any other contents present in it. Avoid taking TENOFOVIR ALAFENAMIDE if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using TENOFOVIR ALAFENAMIDE as TENOFOVIR ALAFENAMIDE may cause dizziness, affecting your ability to drive or use machines. TENOFOVIR ALAFENAMIDE is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.
Drug-Drug Interactions: TENOFOVIR ALAFENAMIDE may interact with an antibiotic (e.g. tobramycin, pentamidine, vancomycin), antifungal medicines (e.g. amphotericin B), antiviral disease (e.g. foscarnet, ganciclovir), medications used to treat hepatitis B virus (e.g. adefovir), pain killer (e.g. ibuprofen). The relevance of a particular drug interaction varies from person to person.
Drug-Food Interactions: Avoid drinking alcohol. Consuming alcohol while using TENOFOVIR ALAFENAMIDE may worsen the condition.
Drug-Disease Interactions: TENOFOVIR ALAFENAMIDE should not be used in patients with bone disease or severe liver or kidney diseases.
Avoid drinking alcohol. Consuming alcohol while using TENOFOVIR ALAFENAMIDE may worsen the condition.
TENOFOVIR ALAFENAMIDE is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels that the benefit to you outweighs the risk. You should not take TENOFOVIR ALAFENAMIDE without the doctor's advice.
Consult your doctor, and there is no substantial research yet on the use of TENOFOVIR ALAFENAMIDE in breastfeeding/nursing mothers.
TENOFOVIR ALAFENAMIDE can cause dizziness. If you feel dizzy when taking TENOFOVIR ALAFENAMIDE, do not drive and use any tools or machines.
Consult your doctor before taking TENOFOVIR ALAFENAMIDE if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.
Consult your doctor before taking TENOFOVIR ALAFENAMIDE if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them to you.
Should not use TENOFOVIR ALAFENAMIDE in children below 12 years of age.
Hepatitis B: Hepatitis B is a potentially fatal liver infection caused by the hepatitis B virus (HBV). It is highly contagious (spreads from one person to another) and spreads by intimate contact with an infected individual, direct contact with infected blood, use of a contaminated needle, use of an infected razor/other personal objects, or transmission from mother to baby during birth. The virus can survive outside the body for up to 7 days. Chronic hepatitis B develops slowly, and symptoms may not be obvious until complications arise. Hepatitis B symptoms might occur three months after being exposed to the infection and can continue for two to twelve weeks. Chronic hepatitis B consequences include liver failure, liver cancer, and liver cirrhosis (scarring). Hepatitis B can be prevented by taking the vaccination.