Telmisartan+rosuvastatin
About Telmisartan+rosuvastatin
Telmisartan+rosuvastatin is used to treat high blood pressure associated with high cholesterol levels. Hypertension, or high blood pressure, is a chronic condition in which the force exerted by the blood against the artery wall is high. High cholesterol, known as hyperlipidemia, occurs when there is an excess of unhealthy cholesterol in the blood.
Telmisartan+rosuvastatin is a combination of Telmisartan and Rosuvastatin. Telmisartan works by blocking the action of a hormone called angiotensin II in the body, which causes the narrowing of blood vessels and leads to high blood pressure. Rosuvastatin works by blocking liver enzymes (HMG-CoA-reductase), causing the liver to produce less cholesterol. Thus, Telmisartan+rosuvastatin lowers the levels of lipids known as cholesterol and triglycerides.
In some cases, you may experience an allergic reaction, low blood pressure, skin itching, and decreased platelet cell count (thrombocytopenia). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Before starting Telmisartan+rosuvastatin, please inform your doctor if you have kidney disease or have undergone a kidney transplant. Renal artery stenosis(narrowing of the blood vessels to one or both kidneys), liver disease, and heart trouble. Do not take Telmisartan+rosuvastatin on your own as self-medication.
Uses of Telmisartan+rosuvastatin
Medicinal Benefits
- Telmisartan+rosuvastatin is used in patients suffering from coexisting Hypertension (High blood pressure) & Hyperlipidemia (High levels of cholesterol).
- Telmisartan+rosuvastatin improves patient compliance due to ease of dosing.
- Telmisartan & Rosuvastatin are the latest drugs for lowering blood pressure and blood cholesterol, offering minimal side effects & more beneficial effects on a patient.
- Telmisartan lowers blood pressure by blocking switches/receptors of Angiotensin-Converting Enzyme II, which is responsible for narrowing the blood vessels and increasing blood pressure.
- Rosuvastatin, on the other hand, acts by blocking an enzyme in the liver called HMG CoA reductase, which is responsible for the formation of cholesterol at high levels.
Directions for Use
- It can be taken with or without food as advised by a doctor.
- Adhere to your doctor's guidance regarding the dosage and timing of this medication for optimal effectiveness.
- Swallow Telmisartan+rosuvastatin as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Telmisartan+rosuvastatin
- Nausea
- Dizziness
- Headache
- Constipation
- Stomach pain and discomfort
- Weakness
- Muscle pain
- Elevated potassium levels in the blood
- Elevated glucose levels in the blood
Drug Warnings
- Do not take Telmisartan+rosuvastatin if you are allergic to any of its contents.
- Talk to your doctor or pharmacist before taking Telmisartan+rosuvastatin if you have undergone a kidney transplant.
- If you have severe respiratory failure, diabetes, thyroid, liver, kidney, or heart problems, raised aldosterone levels (water and salt retention in the body along with imbalance of various blood minerals), or renal artery stenosis, or if you regularly drink large amounts of alcohol, inform your doctor before taking Telmisartan+rosuvastatin.
- Consult your doctor if you are pregnant or breastfeeding.
- Telmisartan+rosuvastatin may cause drowsiness and dizziness, so drive only if you are alert.
- Avoid consuming alcohol along with Telmisartan+rosuvastatin as it could lead to increased dizziness and sleepiness.
- Keep your doctor informed about your health condition and medicines to rule out any side effects.
Drug Interactions
Drug-Drug Interaction: Care should be exercised when Telmisartan+rosuvastatin is administered in combination with warfarin or clopidogrel (blood thinner), fibrates (gemfibrozil, fenofibrate), a medicine used to lower cholesterol (ezetimibe), antacid (aluminium hydroxide, magnesium hydroxide), erythromycin, fusidic acid (antibiotic), oral contraceptive pills, regorafenib (anti-cancer), anti-viral or anti-HIV drug (like ritonavir, lopinavir, atazanavir, simeprevir, ombitasvir, paritaprevir, dasabuvir, velpatasvir, grazoprevir, elbasvir, glecaprevir, pibrentasvir) muscle relaxant (tizanidine), antibiotics (trimethoprim), potassium supplements (potassium acetate, potassium acid phosphate, potassium bicarbonate, potassium chloride, potassium citrate, potassium gluconate, potassium iodide, and potassium phosphate).
Drug-Food Interaction: Care should be exercised when Telmisartan+rosuvastatin is taken with grape juice & fish oil. Alcoholic beverages should be avoided with Telmisartan+rosuvastatin. It may interact with potassium salt substitutes and potassium supplements, resulting in hyperkalemia (high levels of potassium in the blood).
Drug-Disease Interaction: Telmisartan+rosuvastatin should be taken with caution if you have kidney problems, diabetes, thyroid gland problems (hypothyroidism), muscular problems (like rhabdomyolysis, myopathy), blood in the urine (haematuria), and protein in the urine(proteinuria). People with diabetes, cholestasis (liver disease due to the blocked flow of bile), or impaired kidney function should consult a doctor before taking Telmisartan+rosuvastatin.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeA patient is advised not to take this drug with alcohol, as it may interact with the telmisartan component of Telmisartan+rosuvastatin and lower blood pressure drastically.
Pregnancy
consult your doctorA patient is advised to take this drug only on a doctor's recommendation as there have been reports of interaction between the foetus and Telmisartan+rosuvastatin in the first three months of pregnancy.
Breast Feeding
consult your doctorA patient is advised to take this drug only on a doctor's recommendation. Not adequate data is available yet. The drug may pass through the mother's milk and affect the children in a negative way.
Driving
cautionA patient is advised to take caution before taking this drug as, in rare cases, it has been found to cause dizziness during treatment with Rosuvastatin. If you feel dizzy, consult your doctor before attempting to drive.
Liver
cautionA patient is advised to take this drug only on a doctor's recommendation as there have been reports of an interaction between the liver and Telmisartan+rosuvastatin.
Kidney
safe if prescribedNo interaction between Telmisartan+rosuvastatin and kidney function has been reported, yet doctor consultation is advised.
Children
consult your doctorIt should be given to children only on a doctor's recommendation, as there is no appropriate data available for its use in children under 12.
Habit Forming
Diet & Lifestyle Advise
- Keep your weight under control with a BMI of 19.5-24.9.
- Do regular physical activity or exercise for at least 150 minutes per week or about 30 minutes most days of the week.
- Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
- Limiting sodium chloride (table salt) intake to 2300 mg per day or less than 1500 mg is ideal for most adults.
- If you are taking alcohol, then only one serving for women and two servings for men is advisable.
- Quitting smoking is the best strategy to lower the risk of heart disease.
- Maintain a low-salt diet and minimise eating processed foods, as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
- Do regular exercise, such as cycling, walking, jogging, dancing, or swimming, for a minimum of 30 minutes daily.
- Chronic stress may also cause high blood pressure. Therefore, avoid stress by adjusting your expectations and reactions to certain situations and by making time for activities you enjoy.
- Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.
- Avoid smoking and alcohol intake.
Special Advise
- Do not take Telmisartan+rosuvastatin if you have diabetes or occasional attacks of low blood pressure.
- Do not take it if you are allergic to telmisartan or if you are pregnant.
Patients Concern
Disease/Condition Glossary
High Blood Pressure (Hypertension): When blood pressure rises, excessive force is applied to the walls of the arteries, causing the heart to work harder to pump blood throughout the body. This results in damage to the blood vessels and heart. If high blood pressure is left untreated, it can lead to stroke, heart attack, heart failure, kidney failure, stroke, and eye problems.
Hyperlipidemia: There are two types of cholesterol found in our body, namely good cholesterol (HDL-high-density lipoprotein) and bad cholesterol (LDL-low-density lipoprotein). Good cholesterol benefits our heart and helps reduce bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an unhealthy balance of cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol-containing foods and drinks, along with genetic factors, are the primary causes of high cholesterol.
FAQs
Telmisartan+rosuvastatin is used in the treatment of high blood pressure associated with high cholesterol levels.
Take the missed dose as soon as possible, or jump to the next dose if it's too late. Never attempt to take a double dose to make up for the missed dose.
No, hair follicles and Telmisartan+rosuvastatin have not been found to interact. If a patient suffers from such a problem, he/she should consult a doctor immediately.
Protein from plant sources has been found beneficial in heat diseases, yet a protein diet from animal sources should be taken only upon consulting with a doctor. Too much of a high-protein diet also disturb lipid levels in the blood.
In rare cases, Telmisartan+rosuvastatin has been linked to disruption of the sleep cycle. If a patient experiences any such discomfort, he/she should consult a doctor immediately.
Telmisartan+rosuvastatin has been found to cause chest pain. Thus, patients with angina pectoris should consult a doctor before using this medication.
Telmisartan+rosuvastatin has been found to interact with antibacterial medication (fusidic acid) and rarely causes muscle weakness, tenderness, or pain. Patients should consult a doctor before using this medication.
No, do not take any supplements that contain potassium or potassium salts with Telmisartan+rosuvastatin as telmisartan is known to increase potassium levels in the blood which can lead to hyperkalemia (high potassium levels in the blood). It's best to consult your doctor before taking any supplements to ensure safety.
Yes, there are several dietary restrictions that can help manage high blood pressure. Avoid high-sodium foods like processed foods, fast foods, and canned soups which contain more sodium. Limit alcohol, eat more fruits and vegetables, choose whole grains, include lean proteins like fish, poultry, and tofu in your diet and avoid foods high in saturated and trans fats, such as red meat, butter, and fried foods.
Yes, there are some precautions you should take if you are using ibuprofen and Telmisartan+rosuvastatin together. Monitor blood pressure and kidney function. Always inform your doctor about all the medications you are taking, including over-the-counter drugs like ibuprofen, to avoid potential interactions and side effects.
The common side effects of Telmisartan+rosuvastatin are nausea, dizziness, headache, constipation, stomach pain, weakness, muscle pain, elevated potassium levels in the blood, elevated glucose levels in the blood, elevated liver enzymes. If these side effects persist or worsen, please consult your doctor.
