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UROFOLLITROPIN

About

UROFOLLITROPIN belongs to the class of drugs called hormones used in the treatment of female infertility in women whose ovaries do not produce eggs and in women receiving treatments like IVF (in-vitro fertilization). Infertility is unable to become pregnant after trying for a year. Female infertility may be caused due to different factors affecting ovulation (release of an egg from the ovary), fertilization (fusion of sperm and egg) and implantation (fertilized egg attaches to uterus lining).

UROFOLLITROPIN contains Urofollitropin which works similarly to follicle-stimulating hormone (natural sex hormone). UROFOLLITROPIN increases oestrogen production that stimulates the development of the egg and mature follicle in women having ovulation (release of an egg from the ovary) problems and those undergoing IVF treatments.

Take UROFOLLITROPIN as prescribed by your doctor. You are advised to take UROFOLLITROPIN for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience headache, stomach pain, nausea, vomiting, pelvic pain, hot flushes (sudden feeling of warmth) or inflammation of the throat and nasal passage. Most of these side effects of UROFOLLITROPIN do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to UROFOLLITROPIN or any other medicines, please tell your doctor. Avoid taking UROFOLLITROPIN if you are pregnant or breastfeeding and consult a doctor before taking UROFOLLITROPIN. Avoid taking UROFOLLITROPIN if you have tumours of the pituitary gland, hypothalamus, uterus, breasts or ovaries, vaginal bleeding, uterus fibroids, early menopause, malformations of sexual organs, cysts on ovaries or enlarged ovaries. If you experience weight gain, stomach pain, diarrhoea, nausea, vomiting, difficulty in breathing, decreased urination or swelling in the stomach after a few days of taking UROFOLLITROPIN last dose, please consult a doctor immediately as these might be signs of high levels of activity in the ovaries.

Uses of UROFOLLITROPIN

Treatment of Female infertility

Medicinal Benefits

UROFOLLITROPIN contains Urofollitropin which works similarly to follicle-stimulating hormone (natural sex hormone). UROFOLLITROPIN increases estrogen production that stimulates the development of the egg and mature follicle in women having ovulation (release of an egg from the ovary) problems and those undergoing IVF treatments.

Directions for Use

UROFOLLITROPIN will be usually administered by a healthcare professional. If you are asked to take UROFOLLITROPIN by yourself, then follow instructions given by your doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of UROFOLLITROPIN

  • Headache
  • Stomach pain
  • Nausea
  • Vomiting
  • Pelvic pain
  • Hot flushes (sudden feeling of warmth)
  • Inflammation of throat and nasal passage

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to UROFOLLITROPIN or any other medicines, please tell your doctor. If you have hyperprolactinemia (high levels of prolactin hormone), tumours of the pituitary gland, hypothalamus, uterus, breasts or ovaries, underactive adrenal or thyroid glands, blood clots, vaginal bleeding, uterus fibroids, early menopause, malformations of sexual organs, cysts on ovaries or enlarged ovaries, inform your doctor before taking UROFOLLITROPIN. Avoid taking UROFOLLITROPIN if you are pregnant or breastfeeding and consult a doctor before taking UROFOLLITROPIN. If you experience weight gain, stomach pain, diarrhoea, nausea, vomiting, difficulty in breathing, decreased urination or swelling in the stomach after few days of taking UROFOLLITROPIN last dose, please consult a doctor immediately as these might be signs of high levels of activity in the ovaries.

Drug Interactions

Drug-Drug Interaction: UROFOLLITROPIN may interact with ovary stimulants (clomiphene citrate) and drugs used to prevent premature ovulation (ganirelix).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have hyperprolactinemia (high levels of prolactin hormone), tumors of the pituitary gland, hypothalamus, uterus, breasts or ovaries, underactive adrenal or thyroid glands, vaginal bleeding, uterus fibroids, blood clots, early menopause, malformations of sexual organs, cysts on ovaries or enlarged ovaries, inform your doctor before taking UROFOLLITROPIN.

Drug-Drug Interactions Checker List:

  • CLOMIPHENE
  • GANIRELIX
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of UROFOLLITROPIN with alcohol is unknown. Please consult a doctor before consuming alcohol while using UROFOLLITROPIN.

    • Safety Warning

      Pregnancy

      unsafe

      UROFOLLITROPIN is a category X pregnancy drug and is not recommended for use during pregnancy as it may cause multiple pregnancy (twins, triplets, etc.) and increase the risk of miscarriage, tubal pregnancy, birth defects or premature labour. However, please consult a doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      unsafe

      UROFOLLITROPIN is contraindicated in breastfeeding women. It is unknown whether UROFOLLITROPIN is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding.

    • Safety Warning

      Driving

      safe if prescribed

      UROFOLLITROPIN usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of UROFOLLITROPIN in patients with Liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of UROFOLLITROPIN in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      unsafe

      UROFOLLITROPIN is not recommended for children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid fried and processed foods.
    • Take high-fat dairy such as whole milk instead of low-fat products.
    • Include fibre-rich foods like whole grains, fruits and vegetables in your diet.
    • Avoid refined carbohydrates that are high in sugars.
    • Replace animal proteins (like eggs, fish and meat) with vegetable protein sources (nuts, seeds and beans).
    • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
    • Maintain a healthy weight, do moderate exercise regularly.
    • Avoid smoking and alcohol intake.

    Special Advise

    Blood tests and ultrasound scans are recommended to monitor your response to UROFOLLITROPIN treatment.

    Patients Concern

    Disease/Condition Glossary

    Female infertility: Infertility is unable to become pregnant after trying for a year. Female infertility may be caused due to different factors affecting ovulation (release of an egg from the ovary), fertilization (fusion of sperm and egg), and implantation (fertilized egg attaches to uterus lining). The risk factors for infertility in females include smoking, heavy alcohol consumption, obesity, being underweight, increasing age, or having sexually transmitted infections. Also, certain medical conditions such as uterine fibroids, endometriosis, premature ovarian failure, polycystic ovary syndrome (PCOS), hormonal imbalances, scarring from previous surgery, or pelvic inflammatory disease may cause infertility in females.

    FAQs

    UROFOLLITROPIN is used to treat infertility in women whose ovaries do not produce eggs and in women receiving treatments like IVF (in-vitro fertilization).

    UROFOLLITROPIN contains Urofollitropin that works similar to follicle stimulating hormone (natural sex hormone). UROFOLLITROPIN increases oestrogen production that stimulates the development of egg and mature follicle in women having ovulation (release of egg from ovary) problems and those undergoing IVF treatments.

    You are not recommended to take UROFOLLITROPIN with ganirelix (used to prevent premature ovulation) as co-administration of these two medicines may reduce the effects of UROFOLLITROPIN. However, please consult a doctor before taking UROFOLLITROPIN with other medicines.

    UROFOLLITROPIN alone does not cause ovulation (release of egg from ovaries). UROFOLLITROPIN in combination with other medicine such as human chorionic gonadotrophin (hCG) may stimulate ovulation.

    UROFOLLITROPIN may be used in women undergoing IVF (in-vitro fertilization) treatment to help ovaries develop multiple follicles (egg sacs) where eggs develop. However, please consult a doctor before using UROFOLLITROPIN.

    UROFOLLITROPIN may increase the risk of uterine cancer. However, if you experience any unusual vaginal bleeding, please consult a doctor immediately.

    UROFOLLITROPIN may cause miscarriage, ectopic pregnancy (pregnancy outside the womb), birth defects or multiple pregnancy (twins, triplets). Therefore, avoid UROFOLLITROPIN if you are pregnant and consult a doctor.

    Available Medicines for

    UROFOLLITROPIN

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