Eptacog Alfa (activated)

Eptacog Alfa (activated) is a medicine used to treat or prevent bleeding in people with certain bleeding disorders. It may be prescribed for people with haemophilia A or B who have developed inhibitors, congenital factor VII deficiency, or Glanzmann's thrombasthenia in certain situations. It helps the blood form a clot at the site of bleeding.

This medicine is given directly into a vein. The dose and frequency depend on your bleeding disorder, body weight, severity of bleeding, and whether it is being used around surgery or another procedure. Some people or caregivers may be trained by their healthcare team to prepare and give the medicine at home.

Common side effects may include fever, headache, nausea, changes in blood pressure, or reactions where the injection is given. Consult your doctor right away if you develop signs of an unwanted blood clot, such as sudden chest pain, shortness of breath, swelling or pain in one leg, sudden weakness or numbness, or difficulty speaking.

Before treatment, tell your doctor if you have heart or blood vessel disease, a history of blood clots, liver problems, or a serious infection. Also tell your doctor if you have previously had an allergic reaction to eptacog alfa (activated) or any ingredient in the medicine.

Tell your doctor about all medicines you use, particularly other treatments that help the blood clot. Also tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Eptacog Alfa (activated) helps control bleeding in people whose blood cannot clot normally because of certain bleeding disorders.

• Helps control active bleeding: It promotes clot formation at the bleeding site, helping limit blood loss and tissue damage.
• Helps prevent bleeding during procedures: It may be used before, during, or after surgery or other procedures to reduce the risk of excessive bleeding.
• Provides an option when inhibitors are present: It can help people with haemophilia A or B whose inhibitors prevent certain replacement clotting factors from working effectively.
• Supports treatment of factor VII deficiency: It provides the clotting activity needed to help control or prevent bleeding in people with congenital factor VII deficiency.

• Eptacog Alfa (activated) will be administered by a healthcare professional.
• If self-administration is advised, ask your doctor for complete information regarding the reconstitution of the medicine and its administration.

Common Side Effects (Usually Mild)

• Fever
• Headache
• Nausea
• Changes in blood pressure
• Pain, redness, or discomfort where the injection is given

Serious Side Effects (Consult your doctor right away)

• Sudden chest pain, shortness of breath, or difficulty breathing
• Pain, redness, warmth, or swelling in one leg, which may be signs of a blood clot
• Sudden weakness or numbness, severe headache, confusion, or difficulty speaking
• Severe or persistent chest discomfort or other symptoms of a heart problem
• Hives, severe rash, swelling of the face, lips, tongue, or throat, or difficulty breathing
• Bleeding that continues or becomes worse despite treatment