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Itopride Hydrochloride

About Itopride Hydrochloride

Itopride Hydrochloride is a prescription medicine used to treat symptoms of indigestion, chronic gastritis, and poor gastrointestinal motility. Living with ongoing indigestion or stomach discomfort can affect your daily life, and this medicine helps relieve bloating, early fullness after eating, upper abdominal pain, and heartburn by improving the movement of food through your stomach.

For the best results, take Itopride Hydrochloride exactly as prescribed by your doctor, preferably on an empty stomach about one hour before meals. Eating smaller, more frequent meals and avoiding fatty or spicy foods may also help improve your symptoms.

While using Itopride Hydrochloride, you may experience mild side effects such as diarrhoea, headache, or mild stomach pain. These are usually temporary. However, if you develop yellowing of the skin or eyes, signs of a severe allergic reaction, or other severe symptoms, stop taking the medicine and seek emergency medical attention immediately. 

Before starting treatment, tell your doctor if you have liver or kidney problems. Do not use this medicine if you have active stomach or intestinal bleeding, a bowel obstruction, or a perforation in your digestive tract.

Tell your doctor about all medicines you are taking, as some may reduce the effectiveness of Itopride Hydrochloride. If you are pregnant, breastfeeding, an older adult, or consume alcohol or smoke regularly, discuss this with your doctor before starting treatment.

Uses of Itopride Hydrochloride

Itopride Hydrochloride is used for the treatment of Heartburn, Nausea, Vomiting, and Bloating. The detailed uses of Itopride Hydrochloride are as follows:
• Treatment of Functional Dyspepsia: Itopride Hydrochloride is frequently used to alleviate functional dyspepsia symptoms such as pain, bloating, and nausea.
• Management of Gastroesophageal Reflux Disease: Itopride Hydrochloride aids in the treatment of GERD, such as heartburn and acid ingestion, by increasing stomach motility and decreasing the frequency of reflux events.
• Relief from Nausea and Vomiting: Itopride Hydrochloride significantly reduces nausea and vomiting caused by gastroenteritis and chemotherapy, thereby regulating digestive function.
• Postoperative Gastric Motility Disorders: Itopride Hydrochloride can also be used to treat patients who have delayed gastric emptying following surgery.
• Gastroparesis Management: Itopride Hydrochloride can be prescribed to treat gastroparesis by improving gastric motility in patients with weak stomach muscles.

Medicinal Benefits

Itopride Hydrochloride offers several benefits by improving stomach motility and relieving symptoms of indigestion and digestive discomfort.

  • Improves digestion: Itopride Hydrochloride helps food move through the stomach more efficiently, reducing bloating, early fullness, and the heavy feeling after meals.
  • Relieves digestive discomfort: By improving stomach emptying, Itopride Hydrochloride helps reduce symptoms such as heartburn, nausea, and upper abdominal discomfort, supporting greater comfort in daily activities.

Directions for Use

  • Itopride Hydrochloride is taken before meals or as advised by your doctor.
  • It is usually taken three times in a day or as prescribed by the doctor.
  • Swallow it as a whole with a glass of water.
  • Do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Itopride Hydrochloride

Common Side Effects (Usually mild):

  • Loose stools or diarrhoea
  • Headache
  • Mild abdominal pain or cramping
  • Nausea or dizziness

 

Serious Side Effects (Consult your doctor right away):

  • Signs of an allergic reaction, such as skin rash, itching, hives, or swelling of the face, lips, and tongue
  • Yellowing of the skin or eyes (signs of liver damage)
  • Unusual breast swelling, tenderness, or breast milk production
  • Severe, persistent dizziness or fainting

Drug Warnings

  • Check before use: Do not take the medicine if the blister pack is torn, punctured, or damaged.
  • Take before meals: Take this medicine on an empty stomach before meals for the best effect.
  • Inform your healthcare provider: Tell your doctor if you are scheduled for any medical tests, as this medicine may affect certain laboratory results.
  • Take care when driving: Avoid driving or operating machinery if you feel dizzy or light-headed after taking this medicine.
  • Do not share your medicine: Never give this medicine to anyone else, even if they have similar symptoms.

Drug Interactions

Some medicines may affect how well Itopride Hydrochloride works. Tell your doctor about all the medicines you are taking before starting treatment.

  • Anticholinergic medicines: Medicines such as atropine or dicyclomine may reduce the effectiveness of Itopride Hydrochloride by slowing stomach movement.
  • Acid-reducing medicines: These medicines generally do not interact directly with Itopride Hydrochloride, but consult your doctor before taking them together.

Drug-Drug Interactions Checker List:

  • DICYCLOMINE
  • TRIHEXIPHENIDYL
  • IPRATROPIUM
  • BELLADONNA ALKALOIDS
  • BENZTROPINE MESYLATE
  • FLAVOXATE
  • ATROPINE
  • SCOPOLAMINE
  • HYOSCYAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      The interaction of alcohol with Itopride Hydrochloride is unknown. Please consult a doctor before consuming alcohol while using Itopride Hydrochloride.

    • Safety Warning

      Pregnancy

      consult your doctor

      Let your doctor know if you are a nursing mother before taking Itopride Hydrochloride; your doctor will decide whether Itopride Hydrochloride can be taken by breastfeeding mothers or not.

    • Safety Warning

      Breast Feeding

      consult your doctor

      Let your doctor know if you are a nursing mother before taking Itopride Hydrochloride; your doctor will decide whether Itopride Hydrochloride can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      Itopride Hydrochloride may cause dizziness or reduce alertness in some people. So, drive only if you are alert after taking Itopride Hydrochloride.

    • Safety Warning

      Liver

      caution

      Take Itopride Hydrochloride with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Itopride Hydrochloride with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      unsafe

      Itopride Hydrochloride is not recommended for children below 16 years as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat smaller meals: Have smaller, more frequent meals instead of large ones to reduce the workload on your stomach.
    • Avoid lying down after meals: Stay upright for at least 2 hours after eating to help prevent acid reflux and stomach discomfort.
    • Choose stomach-friendly foods: Limit fatty, greasy, highly spiced, and acidic foods that may delay stomach emptying or trigger symptoms.
    • Stay active after eating: Take a light walk after meals to support healthy digestion and bowel movement.
    • Keep a food diary: Record your meals and symptoms to help identify and avoid foods that worsen bloating or indigestion.

    Special Advise

    • If you are suffering from rare hereditary Lapp lactase deficiency problems, galactose intolerance or glucose-galactose malabsorption, avoid taking Itopride Hydrochloride as it contains lactose.

    Patients Concern

    Disease/Condition Glossary

    Gastric motility disorder: In the normal digestion condition, the food is moved through the entire digestive tract (food pipe, stomach, small intestine and large intestine) by a rhythmic contraction, i.e. peristalsis movement. This regular movement of the digestive tract is called 'gastric motility.' When an individual suffers from a digestive motility problem, these digestive tract contractions do not work properly, leading to various gastrointestinal issues.

    FAQs

    Itopride Hydrochloride is used to treat dyspepsia (indigestion), bloating (feeling of stomach tightness due to gas), upper abdominal pain, anorexia (eating disorder), heartburn, nausea and vomiting.

    Itopride Hydrochloride contains Itopride, which works by increasing the level of acetylcholine concentration, which in turn increases the gastrointestinal peristalsis movement thereby, accelerating gastric emptying time and eases the movement of food through the entire gastrointestinal tract. Itopride Hydrochloride also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone - CTZ of the brain responsible for inducing vomiting.

    Yes, Itopride Hydrochloride may cause diarrhoea as a common side effect. However, if the condition persists, worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Itopride Hydrochloride to prevent dehydration.

    No, Itopride Hydrochloride is not recommended for patients with gastrointestinal haemorrhage (internal bleeding of intestine and stomach) as it may lead to gastrointestinal perforation (ruptured bowel).

    No, you are not recommended to take Itopride Hydrochloride with dicyclomine as co-administration of these two medicines may reduce the effect of Itopride Hydrochloride. However, please consult your doctor before taking Itopride Hydrochloride with other medicines.

    Itopride Hydrochloride is not recommended for children below 16 years as the safety and effectiveness were not established.

    Itopride Hydrochloride should be used during pregnancy only if prescribed by the doctor. Consult the doctor if you are pregnant, think you may be pregnant or are planning to have a baby.

    Itopride Hydrochloride should be taken for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.

    Itopride hydrochloride is eliminated primarily by the kidneys. Patients with reduced kidney function should be monitored carefully, and the dose should be adjusted accordingly. If you have any kidney-related diseases, please consult the doctor before taking Itopride Hydrochloride.

    Do not take Itopride Hydrochloride if you are allergic to any of its components or if you suffer from gastrointestinal bleeding, obstruction or perforation.

    Itopride Hydrochloride should be taken before meals or as advised by the doctor.

    Itopride Hydrochloride is a gastroprokinetic agent (enhances the movement of food from the mouth through the stomach and intestines) that is used for treating gastrointestinal symptoms.

    Itopride Hydrochloride may cause side effects like diarrhoea, stomach pain, headache, tremor (involuntary movement) and drowsiness. Most of these side effects of Itopride Hydrochloride do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

    Consult the doctor before taking Itopride Hydrochloride if you have pre-existing medical conditions such as Parkinson's disease or internal bleeding of the stomach and intestine.

    Before starting Itopride Hydrochloride, let your doctor know if you are a nursing mother; your doctor will decide whether Itopride Hydrochloride can be taken by breastfeeding mothers or not.

    It is best to avoid alcohol while taking this medicine. Alcohol can irritate your stomach lining, increase acid production, and worsen symptoms like heartburn and bloating, counteracting the benefits of the medication. Talk to your doctor about your alcohol consumption.

    If you experience dizziness, sit or lie down until the feeling passes. Avoid driving, operating heavy machinery, or performing tasks that require mental alertness. If the dizziness persists or worsens, talk to your doctor.

    Yes, in rare cases, this medicine can increase levels of a hormone called prolactin, which can lead to breast swelling, tenderness, or unusual discharge, as well as menstrual irregularities. If you notice these changes, talk to your doctor immediately.

    Yes, by speeding up the emptying of food from your stomach into your intestines, Itopride Hydrochloride can reduce the backward flow of stomach acid into your food pipe, helping to relieve heartburn and acid reflux. Talk to your doctor about whether this is the right treatment for your reflux.

    Some pain relievers, especially opioids, can slow down digestion and oppose the action of this medicine. Other pain relievers may irritate the stomach. Always consult a healthcare professional before combining treatments. Talk to your doctor or pharmacist for personalised advice.

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