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உற்பத்தியாளர்/சந்தைப்படுத்துபவர் :
குமயூன் மருந்துகள் பிரைவேட் லிமிடெட்
உட்கொள்ளும் வகை :
வாய்வழி
திரும்ப அனுப்பும் கொள்கை :
திரும்பப் பெற முடியாது
Drug-Drug Interactions
Drug-Drug Interactions
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How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Taking Ketorolac and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.
How to manage the interaction:
Taking Ketorolac and Coflam MR 400mg/325mg/250mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Ketorolac and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.
How to manage the interaction:
Taking Ketorolac and Coflam MR 400mg/325mg/250mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Combining Meloxicam and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
How to manage the interaction:
Taking Meloxicam and Coflam MR 400mg/325mg/250mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Combining Meloxicam and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
How to manage the interaction:
Taking Meloxicam and Coflam MR 400mg/325mg/250mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
ChlorzoxazoneMorphine
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Using Morphine together with Coflam MR 400mg/325mg/250mg Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Co-administration of Morphine with Coflam MR 400mg/325mg/250mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Using Morphine together with Coflam MR 400mg/325mg/250mg Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).
How to manage the interaction:
Co-administration of Morphine with Coflam MR 400mg/325mg/250mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ChlorzoxazoneTapentadol
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Taking Tapentadol with Coflam MR 400mg/325mg/250mg Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.
How to manage the interaction:
Taking Coflam MR 400mg/325mg/250mg Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
Taking Tapentadol with Coflam MR 400mg/325mg/250mg Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.
How to manage the interaction:
Taking Coflam MR 400mg/325mg/250mg Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
The combined use of Deferasirox and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of developing gastrointestinal ulcers and bleeding.
How to manage the interaction:
Taking Deferasirox and Coflam MR 400mg/325mg/250mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black, tarry stools,swelling, shortness of breath, muscle cramps, tiredness, weakness, confusion, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
The combined use of Deferasirox and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of developing gastrointestinal ulcers and bleeding.
How to manage the interaction:
Taking Deferasirox and Coflam MR 400mg/325mg/250mg Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black, tarry stools,swelling, shortness of breath, muscle cramps, tiredness, weakness, confusion, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenOxaprozin
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
The combined use of Oxaprozin and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
How to manage the interaction:
Co-administration of Oxaprozin and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
The combined use of Oxaprozin and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
How to manage the interaction:
Co-administration of Oxaprozin and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Coadministration of methotrexate with Coflam MR 400mg/325mg/250mg Tablet can increase the effect and side effects of methotrexate.
How to manage the interaction:
Although there is a possible interaction between methotrexate and Coflam MR 400mg/325mg/250mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
Coadministration of methotrexate with Coflam MR 400mg/325mg/250mg Tablet can increase the effect and side effects of methotrexate.
How to manage the interaction:
Although there is a possible interaction between methotrexate and Coflam MR 400mg/325mg/250mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
IbuprofenOmacetaxine mepesuccinate
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
The combined use of Omacetaxine mepesuccinate and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of bleeding.
How to manage the interaction:
Co-administration of Omacetaxine mepesuccinate and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
The combined use of Omacetaxine mepesuccinate and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of bleeding.
How to manage the interaction:
Co-administration of Omacetaxine mepesuccinate and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Taking diclofenac and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of stomach bleeding and ulcers.
How to manage the interaction:
Co-administration of Diclofenac and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
Taking diclofenac and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of stomach bleeding and ulcers.
How to manage the interaction:
Co-administration of Diclofenac and Coflam MR 400mg/325mg/250mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Coflam MR 400mg/325mg/250mg Tablet:
Coadministration of Dasatinib and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of bleeding.
How to manage the interaction:
Using Dasatinib and Coflam MR 400mg/325mg/250mg Tablet together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of Dasatinib and Coflam MR 400mg/325mg/250mg Tablet can increase the risk of bleeding.
How to manage the interaction:
Using Dasatinib and Coflam MR 400mg/325mg/250mg Tablet together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் Substitute
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Product Substitutes
மது
எச்சரிக்கை
மதுவுடன் கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் எடுத்துக்கொள்வது தலைச்சுற்றல் அல்லது மயக்கத்தை ஏற்படுத்தும். இது தவிர, இது நீண்ட காலத்திற்கு எடுக்கப்பட்டால் உங்கள் கல்லீரலையும் சேதப்படுத்தும். எனவே, கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் உடன் மதுபானங்களை உட்கொள்வதைத் தவிர்க்கவும் அல்லது குறைக்கவும்.
கர்ப்பம்
பாதுகாப்பற்றது
கர்ப்ப காலத்தில் கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் பயன்படுத்துவது பரிந்துரைக்கப்படவில்லை, ஏனெனில் கர்ப்பத்தின் கடைசி 3 மாதங்களில் இந்த மருந்தை உட்கொள்வது பிறக்காத குழந்தைக்கு தீங்கு விளைவிக்கும்.
தாய்ப்பால்
எச்சரிக்கை
உங்கள் மருத்துவர் பரிந்துரைத்தால் மட்டுமே கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் எடுத்துக் கொள்ளுங்கள்.
ஓட்டுதல்
பாதுகாப்பற்றது
கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் எடுத்துக் கொண்ட பிறகு உங்களுக்குத் தலைச்சுற்றல், தூக்கம், மயக்கம் அல்லது சோர்வு போன்றவை தெரியவரலாம், ஏனெனில் இதில் மயக்கத்தை ஏற்படுத்தும் பாராசிட்டமால் உள்ளது. எனவே, இதில் நீங்கள் கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் எடுத்துக்கொள்வதை நிறுத்திவிட்டு உங்கள் மருத்துவரைத் தொடர்பு கொள்ள வேண்டும்.
கல்லீரல்
எச்சரிக்கை
குறிப்பாக உங்களுக்கு கல்லீரல் நோயின் வரலாறு இருந்தால், கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் எச்சரிக்கையுடன் எடுத்துக்கொள்ள வேண்டும். உங்கள் மருத்துவர் டோஸை சரிசெய்ய வேண்டியிருக்கும்.
சிறுநீரகம்
எச்சரிக்கை
குறிப்பாக உங்களுக்கு சிறுநீரக நோய்கள்/நிலைமைகள் இருந்தால், கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் எச்சரிக்கையுடன் எடுத்துக்கொள்ள வேண்டும். உங்கள் மருத்துவர் டோஸை சரிசெய்ய வேண்டியிருக்கும்.
குழந்தைகள்
எச்சரிக்கை
20 கிலோவுக்கு குறைவான உடல் எடை கொண்ட அல்லது 6 வயதுக்குட்பட்ட குழந்தைகளுக்கு கோஃப்ளம் எம்ஆர் 400மி.கி/325மி.கி/250மி.கி டேப்லெட் முரணாக உள்ளது. இது நீரிழப்பு உள்ள குழந்தைகள் மற்றும் இளம் பருவத்தினருக்கு சிறுநீரக பிரச்சினைகளை ஏற்படுத்தும். குழந்தை நிபுணரால் பரிந்துரைக்கப்பட்டால் மட்டுமே இதைப் பயன்படுத்த வேண்டும்.
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