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Crina-NCR 15 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Crina-NCR 15 mg Tablet may interact with anticonvulsants (carbamazepine, phenytoin), antiviral drugs (nelfinavir, ritonavir), a medicine used to treat Cushing’s syndrome (aminoglutethimide), antibiotics (co-trimoxazole, rifampicin, tetracycline), immunosuppressant (ciclosporin).

Drug-Food Interaction: Crina-NCR 15 mg Tablet may interact with St. John’s wort (herbal medicine used to treat depression). Also, limit the intake of grapefruit juice with Crina-NCR 15 mg Tablet as it may increase the levels of Crina-NCR 15 mg Tablet in the blood.  

Drug-Disease Interactions: Avoid taking Crina-NCR 15 mg Tablet if you have vaginal bleeding, blood clots, severe itching, porphyria (blood disorder), liver problems, angina (chest pain), or if you ever had a heart attack, jaundice, or pemphigoid gestationis (an itchy rash that develops into blisters). If you have asthma, migraine headaches, epilepsy (fits), kidney or heart problems, inform your doctor before taking Crina-NCR 15 mg Tablet.

NorethisteroneAmprenavir
Severe
NorethisteroneBoceprevir
Severe

Drug-Drug Interactions

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NorethisteroneAmprenavir
Severe
How does the drug interact with Crina-NCR 15 mg Tablet:
Coadministration of Amprenavir and Crina-NCR 15 mg Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Crina-NCR 15 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
NorethisteroneBoceprevir
Severe
How does the drug interact with Crina-NCR 15 mg Tablet:
Using Boceprevir and Crina-NCR 15 mg Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with Crina-NCR 15 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Crina-NCR 15 mg Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Crina-NCR 15 mg Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crina-NCR 15 mg Tablet:
Taking griseofulvin with Crina-NCR 15 mg Tablet may reduce blood levels and the effects of Crina-NCR 15 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Crina-NCR 15 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Crina-NCR 15 mg Tablet:
Co-administration of Crina-NCR 15 mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Crina-NCR 15 mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Crina-NCR 15 mg Tablet:
Coadministration of Phenytoin and Crina-NCR 15 mg Tablet may decrease the blood levels of Crina-NCR 15 mg Tablet, which may make Crina-NCR 15 mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Crina-NCR 15 mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Crina-NCR 15 mg Tablet:
Coadministration of Crina-NCR 15 mg Tablet with Topiramate can reduce the blood levels and effects of norethindrone in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Crina-NCR 15 mg Tablet and topiramate together can result in an interaction; it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, hot flashes or vaginal dryness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Crina-NCR 15 mg Tablet:
Coadministration of Crina-NCR 15 mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Crina-NCR 15 mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Crina-NCR 15 mg Tablet:
Coadministration of Crina-NCR 15 mg Tablet and primidone can reduce the blood levels and effects of Crina-NCR 15 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Crina-NCR 15 mg Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Crina-NCR 15 mg Tablet:
Using Etretinate and Crina-NCR 15 mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Crina-NCR 15 mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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