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```tamil கலவை :
ஹைட்ரோகுளோரோதியாசைடு-12.5எம்ஜி + லாசர்டன்-50எம்ஜி
உற்பத்தியாளர்/சந்தைப்படுத்துபவர் :
மன்சாஸ் பார்மாசூட்டிகல்ஸ் பிரைவேட் லிமிடெட்
உட்கொள்ளும் வகை :
வாய்வழி
திரும்பப் பெறும் கொள்கை :
திரும்பப் பெற முடியாது
காலாவதியாகும் தேதி அல்லது அதற்குப் பிறகு :
ஜனவரி-27
Drug-Drug Interactions
Critical
HydrochlorothiazideDofetilide
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Taking Cisapride and Losaline H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Losaline H 50mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Losaline H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Losaline H 50mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Taking Dofetilide and Losaline H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Losaline H 50mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Losaline H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Losaline H 50mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LosartanCaptopril
Severe
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Coadministration of Losaline H 50mg/12.5mg Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of Losaline H 50mg/12.5mg Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Coadministration of Losaline H 50mg/12.5mg Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Losaline H 50mg/12.5mg Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Using enalapril together with Losaline H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Although taking Enalapril with Losaline H 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
Using enalapril together with Losaline H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Although taking Enalapril with Losaline H 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Coadministration of amiloride with Losaline H 50mg/12.5mg Tablet may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).
How to manage the interaction:
Taking amiloride along with Losaline H 50mg/12.5mg Tablet may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of amiloride with Losaline H 50mg/12.5mg Tablet may increase potassium levels in the blood. 9High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).
How to manage the interaction:
Taking amiloride along with Losaline H 50mg/12.5mg Tablet may lead to an interaction, but it can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Co-administration of Losaline H 50mg/12.5mg Tablet with Potassium chloride may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Potassium chloride together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce the intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not discontinue any medications without a doctor's advice.
Co-administration of Losaline H 50mg/12.5mg Tablet with Potassium chloride may increase potassium levels in the blood. High potassium levels can cause hyperkalemia (a high level of the electrolyte potassium in the blood), which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Potassium chloride together can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce the intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Coadministration of Losaline H 50mg/12.5mg Tablet with Benazepril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Benazepril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Losaline H 50mg/12.5mg Tablet with Benazepril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Benazepril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Coadministration of ramipril together with Losaline H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of ramipril together with Losaline H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losaline H 50mg/12.5mg Tablet:
Coadministration of Losaline H 50mg/12.5mg Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of Losaline H 50mg/12.5mg Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losaline H 50mg/12.5mg Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Drug-Food Interactions
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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice
How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Losaline H 50mg/12.5mg Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Losaline H 50mg/12.5mg Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Losaline H 50mg/12.5mg Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice
How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Losaline H 50mg/12.5mg Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Losaline H 50mg/12.5mg Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Losaline H 50mg/12.5mg Tablet.
Product Substitutes
மது
பாதுகாப்பற்றது
தூக்கம், தலைச்சுற்றல் மற்றும் கல்லீரல் பாதிப்பு போன்ற விரும்பத்தகாத பக்க விளைவுகளைத் தவிர்க்க நீங்கள் மது அருந்த வேண்டாம் என்றும் லோசலைன் எச் 50மி.கி/12.5மி.கி மாத்திரை என்றும் பரிந்துரைக்கப்படுகிறது.
கர்ப்பம்
பாதுகாப்பற்றது
கர்ப்ப காலத்தில் லோசலைன் எச் 50மி.கி/12.5மி.கி மாத்திரை பரிந்துரைக்கப்படவில்லை. இந்த மருந்து கருவுக்கு சேதம் விளைவிக்கும் மற்றும் பிறக்காத குழந்தையை (கரு) பாதிக்கலாம்.
தாய்ப்பால் கொடுக்கும் காலம்
எச்சரிக்கை
லோசலைன் எச் 50மி.கி/12.5மி.கி மாத்திரை தாய்ப்பாலில் கலக்கும் என்று அறியப்படுகிறது, ஆனால் குழந்தையின் மீதான அதன் விளைவு தெரியவில்லை. எனவே, தாய்ப்பால் கொடுப்பதற்கு முன், இதைப் பற்றி உங்கள் மருத்துவரிடம் தெரிவிக்கவும்.
ஓட்டுநர்
எச்சரிக்கை
லோசலைன் எச் 50மி.கி/12.5மி.கி மாத்திரை தூக்கம் மற்றும் தலைச்சுற்றலை ஏற்படுத்துகிறது, எனவே நீங்கள் விழிப்புடன் இருந்தால் மட்டுமே வாகனம் ஓட்டவும்
கல்லீரல்
எச்சரிக்கை
குறிப்பாக உங்களுக்கு கல்லீரல் நோய் இருந்தால் அல்லது இருந்திருந்தால், லோசலைன் எச் 50மி.கி/12.5மி.கி மாத்திரை எச்சரிக்கையுடன் எடுத்துக்கொள்ள வேண்டும். உங்கள் மருத்துவ நிலை மற்றும் சிகிச்சைக்கான உங்கள் எதிர்வினையைப் பொறுத்து உங்கள் மருத்துவர் மருந்தளவை மாற்ற வேண்டியிருக்கும்.
சிறுநீரகம்
பாதுகாப்பற்றது
நாள்பட்ட சிறுநீரக நோய் (கடுமையான சிறுநீரகக் குறைபாடு) உள்ள நோயாளிகளுக்கு பரிந்துரைக்கப்படவில்லை. கடுமையான சிறுநீரகக் குறைபாடு உள்ள நோயாளிகளுக்கு பாதுகாப்பு மற்றும் செயல்திறன் நிறுவப்படவில்லை.
குழந்தைகள்
எச்சரிக்கை
18 வயதுக்குட்பட்ட குழந்தைகளுக்கு லோசலைன் எச் 50மி.கி/12.5மி.கி மாத்திரை ஆய்வு செய்யப்படவில்லை. எனவே, இது 18 வயதுக்குட்பட்டவர்களுக்குப் பயன்படுத்தப்படக்கூடாது.
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