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compositionComposition:SUNITINIB-12.5MG
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Prescription Medicine
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Sutib 12.5 Capsule 28's is used to treat cancer of the stomach, bowel, oesophagus, kidney, and hormone-producing cells in the pancreas. It contains sunitinib which works by slowing down the growth of cancer cells. In some cases, this medicine may cause side effects such as dry mouth, stomach upset, nausea, vomiting, diarrhoea, constipation, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SUNITINIB-12.5MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Sutib 12.5 Capsule 28's

Sutib 12.5 Capsule 28's is a prescription medication used to treat certain types of advanced cancers, including gastrointestinal stromal tumours (GIST), advanced kidney cancer, and progressive pancreatic neuroendocrine tumours. It works by targeting specific proteins to help slow down or stop the growth of cancer cells. This medication is designed to manage complex conditions under the strict supervision of a healthcare specialist.

You should take this medication consistently once daily, either with or without food. It is helpful to take it at the same time every day to maintain a steady level of the medicine in your body. Making specific lifestyle adjustments, such as maintaining gentle physical activity and staying well-hydrated, can support your body during treatment.

While taking Sutib 12.5 Capsule 28's, you may experience some common side effects, such as fatigue, diarrhoea, and skin changes. However, you must contact your doctor immediately if you notice serious symptoms like severe chest pain, unusual bleeding, or signs of liver damage. Regular monitoring by your healthcare team is essential to keep you safe during therapy.

Before starting this medicine, tell your doctor if you have a history of heart problems, high blood pressure, bleeding disorders, or thyroid issues. Do not take this if you have severe, uncontrolled medical conditions or are allergic to any of its ingredients. Your doctor will carefully review your health profile to ensure it is safe for you.

This medication can interact with other medicines, such as certain anti-seizure drugs and specific antibiotics, which can change how well the treatment works. You should also avoid drinking alcohol or smoking, as they can worsen side effects like fatigue or stomach irritation. If you are pregnant, breastfeeding, or an older adult, consult your doctor to discuss the risks and benefits before starting treatment.

Uses of Sutib 12.5 Capsule 28's

Your doctor may prescribe Sutib 12.5 Capsule 28's for several specific conditions:

  • Gastrointestinal stromal tumours (GIST): This medicine helps treat this rare stomach and intestinal cancer when other primary treatments have stopped working or cannot be tolerated.
  • Advanced renal cell carcinoma: It is used to treat advanced kidney cancer by slowing the progression of the disease.
  • Pancreatic neuroendocrine tumours: This medication treats progressive, well-differentiated tumours in the pancreas that cannot be removed by surgery or have spread to other parts of the body.

Key Benefits

This medication offers clinical benefits that help manage advanced conditions:

  • Slowing tumour progression: By cutting off the signals that help tumours grow, this medicine can keep the cancer from spreading or getting worse for longer periods.
  • Targeting cancer cells directly: Unlike broad chemotherapy, this therapy focuses on specific proteins, which helps limit damage to healthy cells.
  • Convenient oral administration: Because it is a capsule taken by mouth, you can take your treatment at home without needing frequent hospital visits for infusions.

Directions for Use

  • Take Sutib 12.5 Capsule 28's with or without food as advised by your doctor.
  • Typically, Sutib 12.5 Capsule 28's is taken once daily for 28 days, followed by a 2-week break. This cycle is repeated every 6 weeks, as recommended by your doctor. However, always follow your doctor's instructions regarding dosage and duration.
  • Swallow the capsule as a whole with a glass of water.
  • Do not open, crush or dissolve Sutib 12.5 Capsule 28's.

How Sutib 12.5 Capsule 28's Works

Sutib 12.5 Capsule 28's contains sunitinib, which belongs to a group of medicines known as multi-kinase inhibitors. It works by blocking the activity of specific proteins called receptor tyrosine kinases, which are found on the surface of cancer cells and blood vessels. These proteins act like switches that tell cancer cells to grow and divide. By blocking these proteins, Sutib 12.5 Capsule 28's performs two main actions. First, it prevents the cancer cells from multiplying directly. Second, it stops the growth of new blood vessels that feed the tumour, effectively starving the tumour of the oxygen and nutrients it needs to survive. This dual action helps control the spread of the disease.
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Alcohol

Caution

Do not consume alcohol as it can increase the risk of side-effects.

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Pregnancy

Unsafe

Sutib 12.5 Capsule 28's may cause harmful effects to the unborn baby when used in pregnant women. It is also advised to use reliable contraception to prevent pregnancy while using this medicine.

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Breast Feeding

Unsafe

Sutib 12.5 Capsule 28's may cause harmful effects to the nursing baby when given to breastfeeding mothers. Consult your doctor before using Sutib 12.5 Capsule 28's.

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Driving

Caution

Sutib 12.5 Capsule 28's may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Sutib 12.5 Capsule 28's should be used with caution in patients with liver diseases. The doctor may monitor liver function during the treatment.

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Kidney

Caution

Sutib 12.5 Capsule 28's should be used with caution in patients with kidney diseases. The doctor may monitor kidney function during the treatment.

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Children

Unsafe

Sutib 12.5 Capsule 28's is not recommended for children and adolescents below the age of 18 years.

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Heart

Caution

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Sutib 12.5 Capsule 28's should be given to elderly patients only if prescribed by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Sutib 12.5 Capsule 28's

If you take more than your prescribed dose, seek emergency medical attention or contact a poison control centre immediately. Overdose can lead to severe side effects that require urgent medical care.

Diet & Lifestyle Advise

  • Protect your skin: Use thick, fragrance-free moisturisers on your hands and feet daily to prevent dryness, cracking, and peeling. Avoid extremely hot water when bathing.
  • Practice gentle mouth care: Use a soft-bristled toothbrush and rinse your mouth regularly with a salt and baking soda solution to help prevent mouth sores. Avoid spicy, acidic, or very hot foods.
  • Stay hydrated: Drink plenty of water throughout the day, especially if you experience diarrhoea, to prevent dehydration.
  • Monitor your blood pressure: Keep a daily log of your blood pressure readings at home, as this medicine can cause high blood pressure. Share these logs with your doctor.
health query

Have a query?

How Soon It Starts Working

The time required for Sutib 12.5 Capsule 28's to start to work: The time required for Sutib 12.5 Capsule 28's to show its action is unknown. The time for which the effects of Sutib 12.5 Capsule 28's last: The duration of action for Sutib 12.5 Capsule 28's is clinically unknown.

What if you forget to take Sutib 12.5 Capsule 28's

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose completely and take your next dose at your usual time. Do not take two doses at once to make up for a missed one.

Storage

•Store this medicine at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the capsules in their original container, tightly closed, to protect them from moisture and light.

Drug Warnings

  • Inspect the Capsules Before Use: Do not take Sutib 12.5 Capsule 28's if the capsules are cracked, broken, leaking, or otherwise damaged.
  • Avoid Grapefruit Products: Do not consume grapefruit or grapefruit juice while taking Sutib 12.5 Capsule 28's, as they can increase the amount of medicine in your body and raise the risk of side effects.
  • Use Effective Contraception: Use effective contraception during treatment and for the recommended period after your last dose, as Sutib 12.5 Capsule 28's can harm an unborn baby. Talk to your doctor about suitable birth control methods.
  • Inform Your Dentist: Tell your dentist that you are taking Sutib 12.5 Capsule 28's before any dental procedure, as the medicine may increase the risk of jaw bone problems, particularly if you are also receiving bisphosphonates.
  • Inform Healthcare Providers Before Surgery: Tell your doctor or surgeon that you are taking Sutib 12.5 Capsule 28's before any planned surgery, as treatment may need to be temporarily stopped to allow proper wound healing.

verifiedApollotooltip

Sutib 12.5 Capsule 28's may interact with certain medicines, potentially affecting how it works or increasing the risk of side effects. Inform your doctor if you are taking any of the following:

  • CYP3A4 inhibitors: Medicines like ketoconazole, clarithromycin, and certain antivirals can raise the levels of Sutib 12.5 Capsule 28's in your body, increasing the risk of severe side effects.
  • CYP3A4 inducers: Medicines like rifampin, phenytoin, and St. John's wort can lower the levels of Sutib 12.5 Capsule 28's, making your treatment less effective.
  • QT-prolonging drugs: Taking this with certain heart or psychiatric medicines can increase the risk of dangerous irregular heart rhythms.

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verifiedApollotooltip

Certain foods and drinks can affect the way Sutib 12.5 Capsule 28's works. Avoid or discuss the following with your doctor:

  • Grapefruit products: Grapefruit and grapefruit juice directly interfere with how your body breaks down this medicine, which can lead to dangerously high drug levels.

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Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - SUT0120
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