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compositionComposition:VORICONAZOLE-200MG
prescription
Prescription Medicine
info
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VORIFIT 200MG TABLET is used to treat fungal infections. It contains Voriconazole, which kills infection-causing fungi. In some cases, this medicine may cause side effects such as vomiting, headache, nausea, abnormal liver function tests, rash, slow heart rate, and altered vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VORICONAZOLE-200MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About VORIFIT 200MG TABLET

VORIFIT 200MG TABLET is an antifungal medication used to treat serious, deep-seated infections caused by yeast or other fungi. It is commonly prescribed for severe infections that start in the lungs or spread throughout the body. This medication helps clear the infection by stopping the growth of the fungi responsible for the illness.

To ensure the medication works effectively, you must take it consistently at the same times every day as directed by your doctor. It should be taken on an empty stomach, either one hour before or one hour after a meal, because food can prevent your body from absorbing it properly. Protecting your skin from direct sunlight is also a key lifestyle adjustment while taking this medicine, as it can make you highly sensitive to sunburn.

While taking VORIFIT 200MG TABLET, you may experience common side effects such as temporary vision changes, mild skin rashes, or a slightly upset stomach. However, you must contact your doctor immediately if you develop serious side effects, such as a severe skin rash with blistering, dark urine, or yellowing of your skin and eyes, which may point to liver damage.

Before starting this treatment, talk to your doctor if you have a history of liver disease, kidney problems, or an irregular heart rhythm. Do not take this if you are currently taking certain other medications that can cause dangerous heart complications when combined, or if you have had a severe allergic reaction to similar antifungal medicines in the past.

This medicine can interact with many prescription drugs, alcohol, and smoking because of how it is processed by the liver, which can lead to increased side effects or reduced effectiveness. If you are pregnant, breastfeeding, or are an elderly individual, you must consult your healthcare provider to discuss the risks and benefits before starting therapy.

Uses of VORIFIT 200MG TABLET

VORIFIT 200MG TABLET is used to treat serious, deep-seated infections caused by yeast or other fungi. The detailed uses of VORIFIT 200MG TABLET are as follows:

  • Invasive Aspergillosis: Fights severe, invasive lung infections caused by Aspergillus mould.
  • Oesophageal Candidiasis: Treats severe yeast infections in the throat and food pipe, helping restore comfortable swallowing.
  • Serious Systemic Infections: Manages deep tissue or blood infections caused by yeast (like Candida) or other rare fungi.

Key Benefits

VORIFIT 200MG TABLET helps treat fungal infections by stopping the growth and spread of disease-causing fungi. By clearing the underlying infection, it relieves symptoms, supports recovery, and helps prevent serious complications.

  • Helps Treat Fungal Infections Effectively: By inhibiting the growth of fungi, VORIFIT 200MG TABLET helps eliminate the infection, allowing your body's natural defences to recover and restore your health.
  • Relieves Infection-Related Symptoms: As the fungal infection clears, VORIFIT 200MG TABLET helps reduce symptoms such as pain, burning, difficulty swallowing, fever, and discomfort, improving your ability to eat, drink, and carry out daily activities.
  • Helps Prevent the Spread of Serious Infections: By controlling fungal growth, VORIFIT 200MG TABLET helps prevent the infection from spreading to other parts of the body, supporting faster recovery and reducing the risk of complications, especially in severe or invasive fungal infections.
Side effects of Vorifit 200mg Tablet
  • If you notice any changes in your vision, particularly at night, such as difficulty seeing in dim light, blurred vision, or increased sensitivity to glare, inform your doctor immediately. Be sure to share a list of your current medications.
  • Your doctor will assess your symptoms and medical history to determine the underlying cause.
  • A comprehensive eye exam may be advised to rule out any eye conditions. • Medication adjustments may be necessary to alleviate symptoms. Your doctor will review your medication regimen and make recommendations.
  • Vitamin A supplements may be prescribed to support healthy vision. Maintaining adequate vitamin A levels is essential for optimal eye health.
  • Modify your daily routine to cope with night blindness. Avoid challenging activities and explore assistive devices for safety and independence.
  • With proper guidance, you can manage night blindness and minimize its impact.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Chromatopsia needs immediate medical attention as the colours are viewed brightly.
  • Avoid the medication that has led to Chromatopsia.
  • Create a calm environment that helps reduce stress on your eyes.
  • Consume foods that are good for vision, like green leafy vegetables and carrots.
  • Try to avoid consuming alcohol that leads to blurred vision and worsens your condition.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Tell your doctor if you notice any symptoms after taking the medication, such as yellowing of your skin or eyes, dark urine, or stomach pain.
  • Your doctor may change your medication, lower the dose, or temporarily stop the treatment to help alleviate the symptoms.
  • Eat a healthy diet with plenty of fibre from fruits, vegetables, and whole grains.
  • Limit red meat, choose low-fat dairy, and pick healthy fats from nuts, seeds, and fish.
  • Avoid alcohol and foods high in calories, fat, and sugar.
  • Drink plenty of fluids, particularly water.

Directions for Use

  • VORIFIT 200MG TABLET can be taken at least one hour before, or one hour after a meal.
  • Generally, VORIFIT 200MG TABLET is taken twice every day for the best results or as advised by a doctor.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How VORIFIT 200MG TABLET Works

VORIFIT 200MG TABLET contains voriconazole, which works by targeting the structural integrity of the fungal cell. It blocks the action of a specific enzyme that fungi need to produce a vital substance called ergosterol. Ergosterol acts like a protective barrier in the fungal cell membrane, keeping the cell strength and shape intact. Without enough ergosterol, the fungal cell membrane becomes weak, develops holes, and starts to leak. This damage stops the fungus from multiplying and spreading throughout your body. Once the fungus is weakened and prevented from growing, your body's natural immune system can easily target and destroy the remaining fungal cells to clear the infection.
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Alcohol

Unsafe

It is advisable to avoid or limit the intake of alcohol while you use VORIFIT 200MG TABLET.

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Pregnancy

Unsafe

It is unsafe to take VORIFIT 200MG TABLET during pregnancy since it may show harmful effects on the fetus as it is a pregnancy category D drug. There are chances of spontaneous abortions in women treated with VORIFIT 200MG TABLET in the first trimester. Consult your doctor for further advice.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please consult your doctor before taking VORIFIT 200MG TABLET. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Do not drive or operate machines if you experience dizziness or sensitivity to sunlight after taking VORIFIT 200MG TABLET.

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Liver

Consult your doctor

Inform your doctor if you have liver problems before taking VORIFIT 200MG TABLET. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Consult your doctor

Inform your doctor if you have kidney problems before taking VORIFIT 200MG TABLET. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe VORIFIT 200MG TABLET based on your child's age, condition, and body weight.

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Heart

Caution

VORIFIT 200MG TABLET should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using VORIFIT 200MG TABLET.

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Geriatrics

Caution

VORIFIT 200MG TABLET should be taken with extreme caution in geriatric patients. Please consult your doctor before using VORIFIT 200MG TABLET.

What if I have taken an overdose of VORIFIT 200MG TABLET

If you take more than your prescribed dose, seek emergency medical attention immediately. Watch for symptoms like unusual vision changes, extreme sensitivity to light, or a rapid heart rate, and bring your medication bottle with you to the emergency room.

Diet & Lifestyle Advise

  • Protect your skin: This medication increases your sensitivity to sunlight. Wear protective clothing, wide-brimmed hats, sunglasses, and a broad-spectrum, high-SPF sunscreen whenever you go outdoors. Avoid tanning beds entirely.
  • Coordinate doses with meals: Since this medication must be taken on an empty stomach, plan your daily meal times carefully. Avoid eating any food for at least one hour before taking your tablet, and wait at least one hour after taking it before eating again.
  • Avoid alcohol: Do not consume alcohol during your treatment. Both alcohol and this medicine can strain your liver, and combining them increases the risk of serious liver damage.
  • Stay well-hydrated: Drink plenty of water throughout the day to help your kidneys flush out waste products and keep your body functioning optimally.
health query

Have a query?

How Soon It Starts Working

  • The time required for VORIFIT 200MG TABLET to start to work: VORIFIT 200MG TABLET ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of VORIFIT 200MG TABLET last: The effect of VORIFIT 200MG TABLET lasts for 6 hours.

What if you forget to take VORIFIT 200MG TABLET

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you frequently miss doses

Storage

•Store VORIFIT 200MG TABLET tablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F). •Keep the tablets in their original blister packs or container to protect them from light and moisture.

Drug Warnings

  • Do not drive at night: This medication can cause temporary visual disturbances, such as blurriness or sensitivity to light, which can make nighttime driving or operating heavy machinery dangerous.
  • Use reliable birth control: This medicine can cause serious harm to an unborn baby. Women of childbearing age must use highly effective birth control throughout the treatment.
  • Keep up with liver tests: Your doctor will likely order routine blood tests to check your liver function while you are on this medicine. Make sure you do not miss these medical appointments.
  • Check your skin daily: Inspect your skin regularly for any new rashes, peeling, or blisters. Contact your doctor immediately if you notice any unusual skin changes, as these can progress quickly.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): Taking VORIFIT 200MG TABLET with blood thinners may increase the risk of bleeding. Your doctor may recommend closer monitoring of your blood clotting tests and adjust your treatment if necessary.
  • Certain statins and anti-seizure medicines (e.g., carbamazepine): Some cholesterol-lowering statins and anti-seizure medicines may either increase the risk of side effects or reduce the effectiveness of VORIFIT 200MG TABLET. Inform your doctor about all medicines you are taking before starting treatment.
  • Cisapride, pimozide, quinidine, and rifampin: Do not take VORIFIT 200MG TABLET with these medicines. Cisapride, pimozide, and quinidine may increase the risk of life-threatening heart rhythm disturbances, while rifampin can significantly reduce the effectiveness of VORIFIT 200MG TABLET.
VoriconazoleTicagrelor
Critical
VoriconazoleRifampicin
Critical

Drug-Drug Interactions

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VoriconazoleTicagrelor
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using Ticagrelor together with Vorifit 200mg Tablet can significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Vorifit 200mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
VoriconazoleRifampicin
Critical
How does the drug interact with Vorifit 200mg Tablet:
Taking Vorifit 200mg Tablet with Rifampicin can increase blood level of Vorifit 200mg Tablet.

How to manage the interaction:
Although there is an interaction between Vorifit 200mg Tablet with Rifampicin, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VoriconazoleMesoridazine
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using Mesoridazine together with Vorifit 200mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Vorifit 200mg Tablet is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
VoriconazoleIvabradine
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using ivabradine together with Vorifit 200mg Tablet may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vorifit 200mg Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
VoriconazoleNimodipine
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using Nimodipine together with Vorifit 200mg Tablet may significantly increase the risk of serous side effects.

How to manage the interaction:
Taking Nimodipine with Vorifit 200mg Tablet is not recommended, as it may lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medication without consulting a doctor.
VoriconazoleVoclosporin
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using Voclosporin together with Vorifit 200mg Tablet may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Taking Vorifit 200mg Tablet with Voclosporin is not recommended, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
VoriconazoleRitonavir
Critical
How does the drug interact with Vorifit 200mg Tablet:
When Vorifit 200mg Tablet is taken with Ritonavir, the amount of Vorifit 200mg Tablet in the blood may decrease.

How to manage the interaction:
Taking Vorifit 200mg Tablet with Ritonavir is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VoriconazoleCarbamazepine
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using Vorifit 200mg Tablet together with Carbamazepine may significantly reduce the blood levels of Vorifit 200mg Tablet.

How to manage the interaction:
Taking Carbamazepine with Vorifit 200mg Tablet is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
VoriconazoleCisapride
Critical
How does the drug interact with Vorifit 200mg Tablet:
Using Cisapride together with Vorifit 200mg Tablet may significantly increase the blood levels and effects of cisapride.

How to manage the interaction:
Taking Vorifit 200mg Tablet with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
VoriconazoleMethylergometrine
Critical
How does the drug interact with Vorifit 200mg Tablet:
Coadministration of Methylergometrine with Vorifit 200mg Tablet may increase the blood level of Methylergometrine.

How to manage the interaction:
Although Methylergometrine with Vorifit 200mg Tablet can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Food: Take VORIFIT 200MG TABLET on an empty stomach, as food can reduce its absorption and make the medicine less effective. Follow your doctor's instructions regarding the timing of your doses.
  • Grapefruit and grapefruit juice: Avoid grapefruit and grapefruit juice while taking VORIFIT 200MG TABLET, as they may increase the levels of the medicine in your bloodstream, raising the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

No, you should take VORIFIT 200MG TABLET on an empty stomach, either 1 hour before or 1 hour after a meal. Food can significantly decrease how much of the medicine is absorbed into your body. Talk to your doctor or pharmacist if you have trouble scheduling your doses.
Yes, temporary vision changes such as blurriness, sensitivity to light, or altered colour vision are common side effects, especially in the first few weeks of treatment. These changes usually go away after you stop taking the medicine. If you experience severe or persistent vision changes, talk to your doctor.
This medicine makes your skin much more sensitive to ultraviolet (UV) light, which can cause severe sunburns, rashes, or blisters even with short exposure. You should wear protective clothing, use high-SPF sunscreen, and limit your time in direct sunlight. If you develop a skin reaction, talk to your doctor.
It is highly recommended to avoid alcohol while taking this medicine. Both alcohol and VORIFIT 200MG TABLET are processed by the liver, and combining them can increase your risk of liver damage. If you have concerns about this, talk to your doctor.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, talk to your doctor or pharmacist.
No, this medicine is generally not recommended during pregnancy because it can cause harm to an unborn baby. You should use effective birth control while taking this medicine. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor.
Yes, VORIFIT 200MG TABLET has many potential drug interactions that can change how your other medications work or increase the risk of serious side effects. Always provide your healthcare provider with a complete list of all prescription drugs, over-the-counter medicines, vitamins, and herbal supplements you take. Talk to your doctor or pharmacist before starting any new medicine.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - VOR0021
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