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Amlopres AT 25 Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Atenolol, which relax and widen the constricted blood vessels. This ultimately reduces the heart's workload and makes the heart more efficient in pumping blood throughout the body. Also, it blocks stress hormones like adrenaline and epinephrine, thereby slowing down the increased heart rate. Thus, it helps lower high blood pressure, reduces the chances of a heart attack or stroke in the future. It may cause common side effects such as nausea, sleepiness, ankle swelling, headache, palpitations, low blood pressure, cold extremities, flushing (sense of warmth in the ears, face, neck, and trunk), slow heart rate, oedema (swelling), constipation, and tiredness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Amlopres AT 25 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Reducing the amount of time you spend outside and indoors in the cold.
  • keeping your hands warm by donning mittens, gloves, or other protective clothing.
  • Observing a skincare regimen that safeguards your fingers and hands.
  • To improve circulation, give your hands and feet a little massage.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineIdelalisib
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amlopres AT 25 Tablet:
Using Amlopres AT 25 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amlopres AT 25 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Amlopres AT 25 Tablet:
Coadministration of Amlopres AT 25 Tablet and Idelalisib may raise Amlopres AT 25 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Amlopres AT 25 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amlopres AT 25 Tablet:
Coadministration of Amlopres AT 25 Tablet with itraconazole may significantly raise the blood levels and effects of Amlopres AT 25 Tablet.

How to manage the interaction:
Amlopres AT 25 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
How does the drug interact with Amlopres AT 25 Tablet:
Using phenobarbital and Amlopres AT 25 Tablet may drastically lower Amlopres AT 25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Amlopres AT 25 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Amlopres AT 25 Tablet:
Using dolasetron together with Amlopres AT 25 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amlopres AT 25 Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineEnzalutamide
Severe
How does the drug interact with Amlopres AT 25 Tablet:
Using a combination of Amlopres AT 25 Tablet and enzalutamide may drastically lower Amlopres AT 25 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Amlopres AT 25 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Amlopres AT 25 Tablet:
Coadministration of Amlopres AT 25 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Amlopres AT 25 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amlopres AT 25 Tablet:
Coadministration of Amlopres AT 25 Tablet and carbamazepine together may significantly reduce Amlopres AT 25 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlopres AT 25 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Amlopres AT 25 Tablet:
Using Amlopres AT 25 Tablet and mitotane together may drastically lower Amlopres AT 25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlopres AT 25 Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amlopres AT 25 Tablet:
Coadministration of Amlopres AT 25 Tablet and rifampicin together may lower Amlopres AT 25 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlopres AT 25 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-25MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+ATENOLOL-25MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
The consumption of grapefruit juice may slightly increase plasma concentrations of amlodipine. Avoid consumption of grapefruit juice while being treated with Amlopres AT 25 Tablet.

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