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compositionComposition:AMPICILLIN-250MG+CLOXACILLIN-250MG
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Prescription Medicine
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Ampiclox Capsule is used to treat a wide range of bacterial infections. It is a broad-spectrum antibiotic which treats bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections. It contains Ampicillin and Cloxacillin, which works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing bacterial infections. In some cases, it may cause common side effects such as diarrhoea, rashes, nausea, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMPICILLIN-250MG+CLOXACILLIN-250MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ampiclox Capsule

Ampiclox Capsule is an oral antibiotic used to treat a wide range of bacterial infections. It is commonly prescribed to treat infections of the airways, throat, lungs, skin, soft tissues, and ears. By targeting the specific bacteria causing these illnesses, it helps clear the infection and prevents it from spreading further in your body.

To get the best results from Ampiclox Capsule , it must be taken regularly and at evenly spaced intervals as prescribed by your doctor. It is highly recommended to take this medication on an empty stomach, either one hour before or two hours after a meal, because food can significantly decrease how well your body absorbs it. Staying well-hydrated, eating a balanced diet, and getting plenty of rest will support your immune system while you recover.

While taking Ampiclox Capsule , some people may experience mild side effects, such as a mild upset stomach, nausea, or loose stools. These issues are usually temporary, but if you experience severe, watery, or blood-stained diarrhoea or develop a sudden skin rash, stop taking the medicine and consult your doctor immediately. These could be signs of a more serious reaction that requires prompt medical evaluation.

Talk to your doctor or pharmacist before taking this medication if you have a history of kidney disease, liver problems, or a viral infection like mononucleosis. Do not take this if you have had a severe allergic reaction to penicillin or cephalosporin antibiotics in the past, as a cross-allergy can cause a dangerous allergic reaction.

This medicine can interact with other substances, including certain gout medications and cancer treatments. Drinking alcohol during your treatment is not recommended, as it can worsen stomach irritation and dehydrate your body. If you are pregnant, breastfeeding, or managing health conditions in your elderly years, always consult your healthcare provider to ensure this medication is safe for your specific situation.

Uses of Ampiclox Capsule

Ampiclox Capsule is used to treat a wide range of bacterial infections. The detailed uses of Ampiclox Capsule are as follows:

  • Respiratory tract infections: Helps clear bacterial infections in the lungs, throat, and airways, such as bacterial pneumonia or bacterial bronchitis, by stopping bacterial growth. Most cases of bronchitis are caused by viruses and do not require antibiotics, so this medicine should only be used when a bacterial infection is suspected or confirmed by a doctor.
  • Skin and soft tissue infections: Effectively treats painful skin conditions like cellulitis, abscesses, or boils by targeting the bacteria deep within the tissues.
  • Ear, nose, and throat infections: Resolves bacterial sinus infections, tonsillitis, and middle ear infections to relieve pain and swelling.
  • Bone and joint infections: Assists in treating deep bacterial infections within the bones and joints to prevent long-term tissue damage.

Key Benefits

Ampiclox Capsule helps treat bacterial infections by combining two antibacterial agents that work together to stop the growth and spread of infection-causing bacteria. By providing broad-spectrum antibacterial coverage, it helps control infection effectively and supports a faster recovery. This medicine offers several key benefits:

  • Provides Broad-Spectrum Antibacterial Protection: Ampiclox Capsule works against a wide range of bacteria responsible for common infections. The combination of two active ingredients enhances antibacterial activity and may help treat infections that are less responsive to certain single-agent antibiotics.
  • Helps Relieve Infection-Related Symptoms: By controlling the underlying bacterial infection, Ampiclox Capsule helps reduce symptoms such as pain, swelling, redness, fever, and discomfort. As the infection improves, you may experience greater comfort and improved day-to-day functioning.
  • Supports Faster Recovery and Prevents Spread: Effective treatment with Ampiclox Capsule helps clear the infection and reduces the risk of it worsening or spreading to nearby tissues. This can promote a quicker return to normal activities and support overall recovery.
Side effects of Ampiclox Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Managing Medication-Triggered Moniliasis (a yeast infection): A Step-by-Step Guide:
  • If you experience symptoms like itching, burning, redness, or discharge after taking medication, consult your doctor immediately and share your symptoms, medication regimen, and medical history.
  • Your doctor will assess your medication regimen to determine if it's contributing to the moniliasis and identify the best course of action to manage your condition.
  • Your doctor may prescribe antifungal medications or recommend other treatments to help clear up the infection. They may also suggest self-care measures to help manage symptoms and prevent future infections.
  • If your condition doesn't improve or persists, consult your doctor and report it. Your doctor will assess your progress, adjust your treatment plan, and provide advice to ensure the best outcome.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.

Directions for Use

Always follow your doctor's exact instructions when taking this medication. Below are the standard guidelines for using this oral treatment safely:

  • Swallow the capsule or tablet whole with a full glass of water. Do not crush, chew, or break it.
  • Take this medicine on an empty stomach, either 1 hour before or 2 hours after a meal, to ensure your body absorbs the full dose.
  • Try to take your doses at the same times every day to maintain a steady level of the medicine in your bloodstream.
  • Complete the entire course of treatment prescribed by your doctor, even if you start feeling better after a few days. Stopping the medicine too early can cause the infection to return and become harder to treat.

How Ampiclox Capsule Works

This oral medication combines two active ingredients, ampicillin and cloxacillin, to fight bacterial infections effectively. Each component works in a unique way to defeat the bacteria causing your illness. Ampicillin works by interfering with the construction of the bacterial cell wall, which is essential for the bacteria's survival. Without a stable cell wall, the bacteria cannot withstand the pressure inside their cells, causing them to rupture and die. Some bacteria produce protective enzymes called beta-lactamases that can destroy many penicillin-type antibiotics. Cloxacillin has a molecular structure that makes it resistant to breakdown by many of these enzymes (a property known as steric hindrance). This allows cloxacillin to remain active against susceptible beta-lactamase-producing bacteria while working alongside ampicillin to help clear the infection.
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Alcohol

Unsafe

Limit consuming alcohol while taking Ampiclox Capsule to avoid unpleasant side-effects.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant; your doctor will prescribe Ampiclox Capsule only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor if you are breastfeeding; your doctor will decide if Ampiclox Capsule can be taken by breastfeeding mother's or not.

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Driving

Safe

Ampiclox Capsule does not affect your ability to drive.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease before taking Ampiclox Capsule .

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment/kidney disease before taking Ampiclox Capsule .

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Children

Safe if prescribed

Ampiclox Capsule is safe for children if prescribed by a doctor. The dose and duration may vary depending upon the age and severity of the infection.

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Heart

Consult your doctor

Please consult your doctor before using Ampiclox Capsule if you have pre-existing heart problems. Your doctor will prescribe Ampiclox Capsule if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Ampiclox Capsule to geriatric patients. Your doctor will prescribe Ampiclox Capsule if the benefits outweigh the risks.

What if I have taken an overdose of Ampiclox Capsule

Do not take more than the prescribed dose of Ampiclox Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Drink plenty of fluids, especially water, to stay hydrated and help your kidneys process and clear the medication efficiently.
  • Avoid drinking alcohol while taking this antibiotic, as it can irritate your stomach, cause nausea, and slow down your natural recovery process.
  • Consider consuming probiotic-rich foods like plain yoghurt, or talk to your pharmacist about a probiotic supplement to support your gut health. Keep a gap of at least two hours between taking your antibiotic and consuming probiotics.
  • Get adequate rest and avoid strenuous physical exertion to allow your body's immune system to focus on clearing the infection.

Health Queries

I injured my knee in a fall and am experiencing a severe burning sensation that prevents me from sleeping, despite applying Soframycin cream and taking Ampiclox 500mg. What soothing topical creams and oral medications can I use to relieve the burning and help the wound heal?

Veda Maddala

Veda Maddala

M Pharmacy

The burning sensation is likely due to exposed nerve endings from the fall or skin irritation from the topical cream. I recommend stopping the antibiotic cream, as it can sometimes cause local allergic reactions. To soothe the area, apply a thin layer of sterile petroleum jelly; keeping the wound moist protects the nerves and aids healing. For oral pain relief to help you sleep, you can take paracetamol or ibuprofen to target pain and inflammation. Please consult a doctor before continuing the oral antibiotic, as it may be unnecessary and cause side effects. If you observe spreading redness, swelling, or pus, have a healthcare professional evaluate it.
health query

Have a query?

How Soon It Starts Working

The time required for Ampiclox Capsule to start to work: Ampiclox Capsule ideally shows its action within 30 minutes after administration. The time for which the effects of Ampiclox Capsule last: The effect of Ampiclox Capsule lasts for 6 hours.

What if you forget to take Ampiclox Capsule

If you miss a dose, take it as soon as you remember. If it is almost time for next dose, skip the missed dose and take next dose at regular time.

Storage

•Store Ampiclox Capsule at room temperature, strictly between 15°C and 30°C. •Keep the medication in its original packaging or blister pack to protect it from direct sunlight and moisture.

Drug Warnings

  • Do not share this antibiotic with anyone else, even if they have the same symptoms, as misuse can lead to dangerous side effects or ineffective treatment.
  • Check the expiration date on the package before every use; do not take this medication if it has expired.
  • If you use hormonal contraception and develop severe diarrhoea or vomiting during treatment, consult your doctor or pharmacist, as these symptoms may affect contraceptive absorption and effectiveness.
  • Do not use over-the-counter antidiarrhoeal products if you develop severe diarrhoea while taking this medicine, as they can lock toxins in your body and make the condition worse.
  • Inform your healthcare provider if you are scheduled for any medical tests, as this medicine can occasionally interfere with certain laboratory urine tests.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Methotrexate: May increase the amount of methotrexate in your blood, which can raise the risk of severe, toxic side effects.
  • Allopurinol: Combining this with your antibiotic increases the risk of developing a widespread allergic skin rash.
  • Oral Contraceptives: A reduction in the effectiveness of hormonal contraceptives has historically been considered a precaution with some antibiotics. However, current evidence does not strongly support a clinically significant interaction for most penicillin antibiotics. If you experience severe diarrhoea or vomiting while taking Ampiclox Capsule , contraceptive effectiveness may be affected due to reduced absorption. Consult your doctor or pharmacist if you have concerns about contraception during treatment.
  • Probenecid: May slow down the clearing of this antibiotic by your kidneys, leading to higher and longer-lasting levels of the medicine in your body.

Drug-Food Interactions:

  • Food: Eating meals close to taking this medicine reduces how much of the active ingredients enter your bloodstream, making the treatment less effective.

Drug-Disease Interactions:

  • Penicillin Allergy: Do not take this if you have a known history of severe allergic reactions to penicillin or cephalosporin antibiotics.
  • Mononucleosis: Patients with this viral infection are highly likely to develop a widespread skin rash if they take this medicine.
  • Kidney Disease: If your kidneys do not function properly, this medicine may build up in your body, meaning your doctor may need to adjust your dose.
Amoxicillin + DicloxacillinDoxycycline
Severe
Amoxicillin + DicloxacillinBCG vaccine
Severe

Drug-Drug Interactions

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Amoxicillin + DicloxacillinDoxycycline
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of amoxicillin and Dicloxacillin with doxycycline may reduce the effectiveness of amoxicillin.

How to manage the interaction:
Although there is a possible interaction between Amoxicillin and Dicloxacillin with Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
Amoxicillin + DicloxacillinBCG vaccine
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of BCG vaccine with Amoxicillin and Dicloxacillin may reduce the effect of BCG vaccine.

How to manage the interaction:
Although there is an interaction, BCG vaccine can be taken with Amoxicillin and Dicloxacillin if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
Amoxicillin + DicloxacillinMethotrexate
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of methotrexate with amoxicillin and Dicloxacillin can increase the levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate with Dicloxacillin and amoxicillin, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as unusual bleeding or bruising, chills, fever, body pains, consult a doctor immediately. Do not stop using medications without a doctor's advice.
Amoxicillin + DicloxacillinCholera, live attenuated
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of Amoxicillin and Dicloxacillin with Cholera, live attenuated may reduce the activity of the vaccine.

How to manage the interaction:
Although there is a possible interaction between Amoxicillin and Dicloxacillin with Cholera, live attenuated, it can be taken if advised by the doctor. It is advised to receive cholera vaccine, live until at least 14 days after completion of Amoxicillin and Dicloxacillin therapy. Do not discontinue the medication without consulting a doctor.
Amoxicillin + DicloxacillinDicoumarol
Severe
How does the drug interact with Ampiclox Capsule:
Taking Amoxicillin and Dicloxacillin with Dicoumarol can reduce the effectiveness of Dicoumarol.

How to manage the interaction:
Although there is an interaction, Dicoumarol can be taken with Amoxicillin and Dicloxacillin if prescribed by the doctor. However, if you experience chest discomfort, sudden loss of vision, or pain, redness, swelling in an extremity, breathing difficulty, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Ampiclox Capsule is used to treat a wide range of bacterial infections. It is used to treat bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections.
Ampiclox Capsule works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.
Diarrhoea might be a side-effect of Ampiclox Capsule . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Ampiclox Capsule and consult your doctor. Do not take anti-diarrhoeal medicine on your own.
Even if you feel better, it is recommended to complete the course of Ampiclox Capsule as prescribed by the doctor as it is an antibiotic, and stopping it in between may lead to antibiotic resistance.
Pseudomembranous colitis (swelling or inflammation of the large intestine) has been reported with the use of antibiotics. If you experience prolonged or significant diarrhoea with abdominal cramps, stop taking Ampiclox Capsule and consult your doctor immediately.
Ampiclox Capsule may affect certain laboratory test results. Inform the person doing the tests that you are taking Ampiclox Capsule .
Ampiclox Capsule may affect the gut flora leading to decreased oestrogen reabsorption and lowered efficacy of combined oral contraceptives. Use other methods of contraception while on treatment with Ampiclox Capsule . Consult your doctor if you have any concerns.
Your doctor will determine the duration of your treatment. If you have any concerns about using Ampiclox Capsule , consult your doctor.
Ampiclox Capsule is not recommended as it is ineffective against colds, flu, or other viral infections. Using antibiotics unnecessarily increases the risk of developing antibiotic-resistant infections in the future. Therefore, please consult a doctor before use. Do not self-medicate.
Ampiclox Capsule should be taken 30 to 60 minutes before meals as food can reduce absorption or as advised by your doctor.
No, they are not the same. Ampiclox Capsule is a combination of ampicillin and cloxacillin. While amoxicillin is a single antibiotic. Ampiclox Capsule and amoxicillin are penicillin-based antibiotics but are used for treating bacterial infections.
The dose and frequency will be decided by your doctor based on your medical condition. Follow your doctor’s instructions.
Ampiclox Capsule usually begins to work shortly after you start taking it. However, it may take a few days to eliminate all harmful bacteria and improve your symptoms.
Ampiclox Capsule should be avoided with methotrexate, used to treat rheumatoid arthritis, psoriasis, and certain types of cancer, as their combination may lead to serious side effects. However, you are recommended to consult your doctor before taking other medicines with Ampiclox Capsule to avoid potential interactions.
Ampiclox Capsule causes side effects such as diarrhoea, rash, nausea and vomiting. These gradually reduce over time. However, consult the doctor if persists longer durations.
Ampiclox Capsule may interact with sulfonamides, bacteriostatic medications, oral contraceptives, medicines that lower uric acid levels (like allopurinol), and aspirin (pain reliever). Therefore, consult your doctor before taking other medicines while on treatment with Ampiclox Capsule .
If you are pregnant, breastfeeding, think you might be pregnant or are planning to have a baby, consult your doctor for advice before using Ampiclox Capsule . It is recommended by doctor only if the benefits overweigh the risks.
If you have taken more than the recommended doses of Ampiclox Capsule , seek medical help right away by contacting your doctor.
It is best to avoid alcohol. Alcohol can worsen common side effects like nausea and stomach upset, and it can dehydrate your body, which may prolong your recovery time.
Do not take this medicine if you have a known allergy to penicillin or cephalosporins. Doing so can trigger a severe, life-threatening allergic reaction. Talk to your doctor about safer alternative treatments.

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Country of origin

India

Manufacturer/Marketer address

Dr. Annie Besant Road, Mumbai - 400 030
Other Info - AMP0054
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