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compositionComposition:AMOXAPINE-50MG
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Prescription Medicine
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Demo 50 mg Tablet is used to treat depression, anxiety, and agitation. It contains Amoxapine, a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for mental health and mood changes. This medicine helps improve mood and feelings.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMOXAPINE-50MG

Manufacturer/Marketer :

D D Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Demo 50 mg Tablet

Demo 50 mg Tablet is a prescription medication primarily used to treat depression. It is especially helpful for patients experiencing depressive symptoms accompanied by anxiety, tension, or agitation. This medication belongs to a class of drugs that help restore balance to certain chemical messengers in the brain.

To get the best results, you must take Demo 50 mg Tablet consistently every day exactly as your doctor prescribes. You can take this medicine with or without food, though taking it with meals can help prevent stomach upset. Incorporating a regular sleep schedule, eating a balanced diet, and engaging in light daily physical activity can also support your treatment outcomes.

While taking this medicine, some people may experience common side effects like drowsiness, dry mouth, or constipation. If you face specific serious side effects, such as unusual muscle stiffness, tremors, a rapid heartbeat, or sudden changes in your mental state, you should consult your doctor right away.

Before you begin taking Demo 50 mg Tablet , tell your doctor if you have a history of heart disease, seizures, glaucoma, or difficulty urinating. Do not take this if you are currently recovering from a recent heart attack. It is also important that you do not take this if you have used certain other antidepressant medicines within the last two weeks.

This medicine can interact with other drugs that make you sleepy, and drinking alcohol while taking it can dangerously increase drowsiness. Additionally, smoking may change how quickly your body processes this medication. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, you should consult your doctor or pharmacist to discuss the risks and benefits before starting treatment.

Uses of Demo 50 mg Tablet

Demo 50 mg Tablet is used to treat depression. The detailed uses of Demo 50 mg Tablet are as follows:

  • Depression: Demo 50 mg Tablet helps relieve persistent sadness, loss of interest in activities, and fatigue by balancing critical chemicals in the brain.
  • Depression with anxiety or agitation: It helps calm nervous tension and restlessness that frequently occur alongside depressive disorders.
  • Severe or psychotic depression: It helps manage severe depressive states, including those where individuals experience distorted thoughts or see and hear things that are not there.

Key Benefits

Demo 50 mg Tablet helps manage depression and anxiety by restoring the balance of important brain chemicals. With regular use as prescribed, it helps improve mood, reduce anxiety symptoms, and support better emotional well-being.

  • Improves Mood: By balancing key neurotransmitters in the brain, this medicine helps reduce symptoms of depression, improve emotional well-being, and make it easier to return to daily activities.
  • Reduces Anxiety Symptoms: This medicine helps relieve anxiety-related symptoms such as excessive worry, restlessness, and physical tension, promoting a greater sense of calm.
  • Promotes Better Sleep and Daily Functioning: By improving mood and reducing anxiety, this medicine supports healthier sleep patterns, improves concentration, and helps you feel more rested and better able to manage everyday responsibilities.
Side effects of Demo 50 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost Vitamin K with leafy greens (spinach, kale), broccoli, cauliflower, and cabbage.
  • Include iron-rich foods like lean red meat, legumes, fortified cereals, and dark leafy greens.
  • Stay hydrated by drinking plenty of water.
  • Add Vitamin C-rich foods (citrus fruits, bell peppers) to enhance iron absorption.
  • Limit excessive alcohol and blood-thinning foods like garlic and certain herbs.
  • Engage in gentle exercise like walking, swimming, or yoga.
  • Monitor injuries and apply pressure to wounds promptly.
  • Schedule regular medical checkups for routine blood tests.

Directions for Use

  • Demo 50 mg Tablet can be taken with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Demo 50 mg Tablet as a whole with a glass of water.
  • Do not break, chew or crush Demo 50 mg Tablet .

How Demo 50 mg Tablet Works

Demo 50 mg Tablet contains amoxapine, which works by increasing the levels of certain natural chemicals in your brain, specifically norepinephrine and serotonin. These chemicals act as messengers between your brain cells and are essential for regulating your mood, emotions, and overall sense of well-being. In addition to boosting these mood-regulating chemicals, Demo 50 mg Tablet blocks a chemical pathway called dopamine. This combined action is highly unique and makes the medicine particularly effective at quieting overactive brain signals, helping to relieve severe anxiety, agitation, and extreme mood disturbances.
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Alcohol

Unsafe

Alcohol should be avoided while on treatment with Demo 50 mg Tablet as it can affect you much more and may make you feel more depressed.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy inform your doctor before taking Demo 50 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

If you are breastfeeding, inform your doctor before receiving Demo 50 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Demo 50 mg Tablet may cause drowsiness and impair your concentration. Hence, it is advised not to drive or operate machines while on treatment with Demo 50 mg Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Demo 50 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Demo 50 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Demo 50 mg Tablet is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

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Heart

Caution

Demo 50 mg Tablet should be avoided if you have heart problems, especially a history of heart attack or arrhythmias. It may cause serious cardiac side effects like QTc prolongation, tachycardia, or sudden death. Always consult your doctor for safer alternatives.

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Geriatrics

Caution

Demo 50 mg Tablet should be used with caution in geriatric patients due to increased sensitivity to side effects like dizziness, confusion, and heart rhythm changes. Close medical supervision is essential to ensure safe use.

What if I have taken an overdose of Demo 50 mg Tablet

In case of an accidental overdose, seek immediate emergency medical attention. Symptoms of an overdose may include extreme drowsiness, confusion, rapid heart rate, severe muscle shaking, or fainting.

Diet & Lifestyle Advise

  • Drink plenty of fluids and consume high-fibre foods, such as fresh fruits, vegetables, and whole grains, to help prevent constipation caused by this medicine.
  • Sip water, suck on ice chips, or chew sugar-free gum to relieve dry mouth symptoms.
  • Completely avoid alcohol while taking this medicine, as it can worsen sedation and dizziness.
  • Stand up slowly from a sitting or lying position to prevent dizziness and reduce your risk of falling.
  • Establish a consistent bedtime routine to support healthy sleep habits, which can aid your recovery from depression.

Health Queries

I have a problem with overthinking again and again. What should I do to control it?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Repeated overthinking often happens when the mind stays stuck on worries, fear about the future, past mistakes, stress, anxiety, or emotional pressure. Many people notice continuous unwanted thoughts at night, difficulty relaxing, poor concentration, irritability, or disturbed sleep. Overthinking can gradually increase mental exhaustion and make even small problems feel harder to manage. Management usually focuses on calming the thought cycle rather than trying to force thoughts to completely disappear. Regular sleep, physical activity, limiting excessive phone use at night and maintaining a structured routine may help reduce mental overload. Some people benefit from journaling, mindfulness practices, breathing exercises, or speaking openly with a trusted person. Breaking large issues into smaller tasks can also reduce mental repetition. If overthinking starts regularly affecting daily work, relationships, appetite or sleep, professional counselling or emotional health support may help detect underlying anxiety or stress cycles. Sudden panic, hopelessness, or thoughts of suicide should never be ignored.
health query

Have a query?

How Soon It Starts Working

The time required for Demo 50 mg Tablet to start to work: The onset time of Demo 50 mg Tablet has not been clinically established. The time for which the effects of Demo 50 mg Tablet last: The duration of Demo 50 mg Tablet ’s effect is clinically not established.

What if you forget to take Demo 50 mg Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Demo 50 mg Tablet tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C).

Drug Warnings

  • Do not stop taking Demo 50 mg Tablet suddenly, as this can cause withdrawal symptoms like headache, nausea, or a general feeling of discomfort.
  • Wear sunscreen and protective clothing when outdoors, as this medication can make your skin more sensitive to sunlight.
  • Do not drive, operate machinery, or perform hazardous activities until you are certain how this medicine affects your alertness.
  • Ask family members or close friends to help monitor you for sudden changes in mood, worsening depression, or unusual behaviors, especially during the first few weeks of treatment.
  • Inform your dentist, surgeon, or emergency room physician that you are taking Demo 50 mg Tablet before undergoing any medical procedures or surgeries.

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you have taken an MAOI antidepressant within the last 14 days, as combining them can cause dangerously high blood pressure or a life-threatening brain reaction.
  • Sedatives and Sleep Medicines: Taking this medication with other drugs that cause drowsiness, such as sleeping pills, opioid pain relievers, or muscle relaxants, can cause extreme sedation and slow breathing.
  • Blood Pressure Medications: Demo 50 mg Tablet may interfere with how certain blood pressure medications work, potentially reducing their effectiveness.
DiclofenacMeloxicam
Critical
DiclofenacAmiloride
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Demo 50 mg Tablet:
Co-administration of Demo 50 mg Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Demo 50 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacAmiloride
Severe
How does the drug interact with Demo 50 mg Tablet:
Taking amiloride with Demo 50 mg Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Demo 50 mg Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Demo 50 mg Tablet:
Co-administration of Demo 50 mg Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacFlurbiprofen
Severe
How does the drug interact with Demo 50 mg Tablet:
Co-administration use of Demo 50 mg Tablet with Flubiprofen may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
There is a possibility of interaction between Demo 50 mg Tablet and Flubiprofen but they can be taken together if your doctor has prescribed them. Consult your doctor immediately if you experience any symptoms like Nausea, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, burning in stomach, acidity, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacPonatinib
Severe
How does the drug interact with Demo 50 mg Tablet:
Taking Demo 50 mg Tablet with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacIbuprofen
Severe
How does the drug interact with Demo 50 mg Tablet:
Taking Demo 50 mg Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacTacrolimus
Severe
How does the drug interact with Demo 50 mg Tablet:
Co-administration of Demo 50 mg Tablet with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacMethotrexate
Severe
How does the drug interact with Demo 50 mg Tablet:
Co-administration of methotrexate with Demo 50 mg Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Demo 50 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacLeflunomide
Severe
How does the drug interact with Demo 50 mg Tablet:
Co administration of Demo 50 mg Tablet with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Demo 50 mg Tablet and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with Demo 50 mg Tablet:
Taking Valdecoxib with Demo 50 mg Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Demo 50 mg Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Consuming grapefruit products may alter how your body breaks down this medicine, potentially increasing the risk of side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDEPRESSANT]

FAQs

It is not known whether Demo 50 mg Tablet is completely safe during pregnancy or while breastfeeding. It should only be used if your doctor believes the benefits outweigh the potential risks. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medicine.
No, you should avoid alcohol while taking this medicine. Alcohol can significantly increase drowsiness, dizziness, and confusion, and it can also make your depression symptoms worse. Talk to your doctor or pharmacist if you have concerns.
Yes, some patients experience an increased appetite and subsequent weight gain while taking this medication. Maintaining a balanced diet and exercising regularly can help manage this side effect. Talk to your doctor if you experience significant changes in your weight.
No, it is advised not to stop taking Demo 50 mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.
Yes, drowsiness is a very common side effect, especially when you first start taking the medicine. Your doctor may recommend taking your dose at bedtime to help manage this. Avoid driving if you feel sleepy, and talk to your doctor if the sleepiness does not improve.
Yes, this medication can affect your heart rhythm and heart rate, particularly if you already have a heart condition. If you experience a very fast or irregular heartbeat, seek medical attention immediately. Talk to your doctor before starting this medicine if you have any heart issues.
Dry mouth is a common side effect of this class of medication. You can manage this by sipping water throughout the day, chewing sugar-free gum, or sucking on ice chips. If the dry mouth is severe or causes dental issues, talk to your doctor or pharmacist.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

G-1/583,585,586 Sitapura Industrial Area, RIICO, Tonk Road, Jaipur (Rajasthan)-302022.
Other Info - DEM0006

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