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Istavel D 5/50 Tablet 10's is used to treat type-2 diabetes mellitus. It contains Dapagliflozin and Sitagliptin. Dapagliflozin lowers blood glucose levels and increases glucose excretion in the urine. By improving insulin levels and lowering glucagon levels (the hormone that raises blood glucose levels), sitagliptin decreases the amount of glucose the liver produces. Thus, it helps control blood sugar levels. Common side effects of this medicine include diarrhoea, hypoglycaemia, headache, nausea, and vomiting.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Istavel D 5/50 Tablet 10's

Istavel D 5/50 Tablet 10's is an oral prescription tablet used to lower blood sugar levels in adults with type 2 diabetes. This medication contains a combination of two active therapies that work together to help control blood glucose. It is prescribed as an addition to diet and exercise to help manage diabetes.

To achieve the best results, you must take Istavel D 5/50 Tablet 10's consistently every day at the same time, exactly as your doctor instructs. You can take this tablet with or without food, though taking it with a meal may prevent an upset stomach. Incorporating a balanced, low-sugar diet and a regular exercise routine is essential to help the medication work effectively.

While taking this medication, you may experience common, mild side effects like a runny nose, sore throat, or mild urinary tract infections. However, you must contact your doctor immediately if you experience serious side effects, such as severe, persistent stomach pain or signs of dehydration.

Before starting Istavel D 5/50 Tablet 10's, talk to your doctor if you have a history of kidney disease, pancreas problems, or heart failure. Do not take this if you have type 1 diabetes, diabetic ketoacidosis, or severe kidney impairment, as it is not designed to treat these conditions.

This medicine can interact with certain blood pressure pills or other diabetes medications, which can increase the risk of low blood sugar or dehydration. You should avoid heavy alcohol consumption because it can increase your risk of severe pancreas irritation or blood sugar fluctuations. Pregnant women, breastfeeding mothers, and elderly individuals should consult their doctor before starting Istavel D 5/50 Tablet 10's to ensure it is safe for them.

Uses of Istavel D 5/50 Tablet 10's

Istavel D 5/50 Tablet 10's is used in the treatment of type-2 diabetes mellitus. The detailed uses of Istavel D 5/50 Tablet 10's are as follows:

  • Type 2 Diabetes Mellitus: Istavel D 5/50 Tablet 10's helps lower daily blood sugar levels by aiding the kidneys in removing excess sugar through urine, helping the pancreas release more insulin, and reducing the amount of sugar the liver produces.

Key Benefits

Istavel D 5/50 Tablet 10's helps improve blood sugar control in adults with type 2 diabetes when used alongside a healthy diet and regular exercise.
Benefits may include:

  • It helps keep blood sugar within your target range and can help improve day-to-day well-being and reduce the risk of diabetes-related complications over time.
  • By keeping your blood sugar stable throughout the day, Istavel D 5/50 Tablet 10's plays a vital role in protecting your long-term health.
  • Maintaining consistent control over your blood glucose levels helps prevent serious diabetes-related complications, such as nerve damage, kidney issues, and vision loss.
  • Additionally, this medication simplifies your treatment plan. Because it combines two active therapies into a single daily tablet, it reduces the number of pills you need to take, making it easier to stick to your daily routine.

Directions for Use

  • Take Istavel D 5/50 Tablet 10's with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Istavel D 5/50 Tablet 10's Works

Istavel D 5/50 Tablet 10's combines two different active mechanisms to manage blood sugar. Dapagliflozin: It targets your kidneys. It stops your kidneys from absorbing sugar back into your blood, which allows your body to filter out excess sugar and release it when you urinate. Sitagliptin: It works on your digestive system and pancreas. It helps your pancreas release more insulin after you eat, which allows your cells to use sugar more effectively. At the same time, it tells your liver to make less sugar, helping to keep your fasting blood sugar in check.
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Alcohol

Unsafe

Avoid consumption of alcohol during treatment with Istavel D 5/50 Tablet 10's as it may cause serious side effects.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before starting treatment with Istavel D 5/50 Tablet 10's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Istavel D 5/50 Tablet 10's on breastfeeding. Hence, if you are a nursing mother, inform your doctor before taking Istavel D 5/50 Tablet 10's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Istavel D 5/50 Tablet 10's may occasionally cause dizziness. Hence, drive only if you are alert after taking this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Istavel D 5/50 Tablet 10's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Istavel D 5/50 Tablet 10's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Istavel D 5/50 Tablet 10's is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

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Heart

Safe

Istavel D 5/50 Tablet 10's is safe to be used in heart conditions. This medicine shows potential benefits in patients with heart failure and other associated conditions.

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Geriatrics

Safe

Istavel D 5/50 Tablet 10's is not generally contraindicated in elderly patients, but caution is advised, and it should be used with careful consideration of potential risks and benefits.

What if I have taken an overdose of Istavel D 5/50 Tablet 10's

If you suspect an overdose, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose may include extreme weakness, shakiness, sweating, or severe dizziness.

Diet & Lifestyle Advise

  • Monitor your carbohydrate intake: Focus on eating complex carbohydrates, like whole grains and non-starchy vegetables, to prevent sudden spikes in your blood sugar.
  • Stay well-hydrated: Because this medication helps your body remove sugar through your urine, you may lose more fluids than usual. Drink plenty of water throughout the day to prevent dehydration.
  • Engage in regular physical activity: Aim for at least 150 minutes of moderate exercise, like brisk walking, per week to help your body use insulin more effectively.
  • Check your feet daily: People with diabetes are prone to foot issues. Wash your feet daily, dry them thoroughly, and inspect them for any cuts, sores, or red spots.
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How Soon It Starts Working

The time required for Istavel D 5/50 Tablet 10's to start to work: Istavel D 5/50 Tablet 10's ideally shows its action within few hours after administration. The time for which the effects of Istavel D 5/50 Tablet 10's last: The effect of Istavel D 5/50 Tablet 10's lasts for 24 hours.

What if you forget to take Istavel D 5/50 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular routine. Do not take a double dose to make up for a missed one.

Storage

•Store Istavel D 5/50 Tablet 10's at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Observe your breathing and energy levels: Report any rapid breathing, deep fatigue, or sudden confusion immediately, as these can be warning signs of a serious condition called diabetic ketoacidosis.
  • Practice good daily hygiene: Because this medication increases sugar in your urine, maintaining clean, dry skin in genital areas is vital to prevent fungal infections.
  • Check your kidney function regularly: Ensure you attend all scheduled blood and urine tests so your doctor can monitor how well your kidneys are filtering this medication.
  • Carry a fast-acting sugar source: Always keep fruit juice, honey, or glucose tablets with you in case you experience sudden symptoms of low blood sugar when taking this with other diabetes medicines.

verifiedApollotooltip
  • Insulin and sulfonylureas: Taking Istavel D 5/50 Tablet 10's with these medications can increase the risk of low blood sugar (hypoglycemia). Your doctor may need to adjust your doses.
  • Diuretics (water pills): These can increase your risk of dehydration and low blood pressure when taken alongside Istavel D 5/50 Tablet 10's.

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verifiedApollotooltip
  • Alcohol: Avoid heavy alcohol consumption, as it can increase the risk of low blood sugar and raise the risk of a dangerous condition called ketoacidosis or pancreatitis.

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - IST0048
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