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తయారీదారు/మార్కెటర్ :
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వినియోగ రకం :
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జనవరి-27
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Drug-Drug Interactions
Critical
HydrochlorothiazideDofetilide
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Taking Cisapride and Losa-H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Losa-H 50mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Losa-H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Losa-H 50mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Taking Dofetilide and Losa-H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Losa-H 50mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Losa-H 50mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Losa-H 50mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LosartanCaptopril
Severe
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of Losa-H 50mg/12.5mg Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of Losa-H 50mg/12.5mg Tablet with Captopril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
LosartanPotassium citrate
Severe
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of Losa-H 50mg/12.5mg Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
Coadministration of Losa-H 50mg/12.5mg Tablet with Potassium citrate can increase potassium levels, which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Potassium citrate together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of Losa-H 50mg/12.5mg Tablet with Trimethoprim can increase potassium levels which can lead to severe conditions like kidney problems.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Trimethoprim together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Losa-H 50mg/12.5mg Tablet with Trimethoprim can increase potassium levels which can lead to severe conditions like kidney problems.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Trimethoprim together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of ramipril together with Losa-H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of ramipril together with Losa-H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Ramipril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of Losa-H 50mg/12.5mg Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Coadministration of Losa-H 50mg/12.5mg Tablet with Quinapril can increase potassium levels which can lead to severe conditions like kidney failure, muscle paralysis, and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Quinapril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes) while taking these medications. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of Losa-H 50mg/12.5mg Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Losa-H 50mg/12.5mg Tablet with Perindopril can increase of kidney problems and irregular heart rhythm.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Perindopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Using enalapril together with Losa-H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Although taking Enalapril with Losa-H 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
Using enalapril together with Losa-H 50mg/12.5mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).
How to manage the interaction:
Although taking Enalapril with Losa-H 50mg/12.5mg Tablet may result in an interaction, they can be taken together if your doctor prescribes it. However, contact a doctor immediately if you experience nausea, vomiting, weakness, tingling of the hands and feet, and feelings of heaviness in the legs. Do not discontinue any medication without consulting a doctor.
Severe
How does the drug interact with Losa-H 50mg/12.5mg Tablet:
Coadministration of Losa-H 50mg/12.5mg Tablet with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
Coadministration of Losa-H 50mg/12.5mg Tablet with Tizanidine can show additive effects which can lower the blood pressure and increase the risk and severity of side effects.
How to manage the interaction:
Taking Losa-H 50mg/12.5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you notice any nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, or irregular heartbeat. While taking these medications, avoid taking a potassium-rich diet (tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes). Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Drug-Food Interactions
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HYDROCHLOROTHIAZIDE-12.5MG+LOSARTAN-50MGPotassium rich foods, Fruit juices
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice
How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Losa-H 50mg/12.5mg Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Losa-H 50mg/12.5mg Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Losa-H 50mg/12.5mg Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt, Grapefruit Juice
How to manage the interaction:
Coadministration of potassium-containing salt substitutes with Losa-H 50mg/12.5mg Tablet may cause high levels of potassium in blood. Also, coadministration of grapefruits and grapefruit juice with Losa-H 50mg/12.5mg Tablet may decrease the efficacy of losartan. Avoid consumption of potassium-containing salt substitutes, grapefruits and grapefruit juice while being treated with Losa-H 50mg/12.5mg Tablet.
మద్యం
అసురక్షిత
మగత, మైకము మరియు కాలేయ దెబ్బతినడం వంటి అసహ్యకరమైన దుష్ప్రభావాలను నివారించడానికి మీరు మద్యం సేవించకూడదని మరియు లోసా-H 50mg/12.5mg టాబ్లెట్ సిఫార్సు చేయబడింది.
గర్భం
అసురక్షిత
గర్భధారణ సమయంలో లోసా-H 50mg/12.5mg టాబ్లెట్ సిఫార్సు చేయబడలేదు. ఈ ఔషధం పిండానికి హాని కలిగించవచ్చు మరియు పుట్టబోయే బిడ్డ (పిండం) పై ప్రభావం చూపుతుంది.
తల్లిపాలు ఇవ్వడం
జాగ్రత్త
లోసా-H 50mg/12.5mg టాబ్లెట్ తల్లి పాలలోకి వెళుతుందని తెలుసు, కానీ బిడ్డపై దాని ప్రభావం తెలియదు. కాబట్టి, తల్లిపాలు ఇవ్వడానికి ముందు, దీని గురించి మీ వైద్యుడికి తెలియజేయండి.
డ్రైవింగ్
జాగ్రత్త
లోసా-H 50mg/12.5mg టాబ్లెట్ మగత మరియు మైకము కలిగిస్తుంది, కాబట్టి మీరు అప్రమత్తంగా ఉంటే మాత్రమే డ్రైవ్ చేయండి
కాలేయం
జాగ్రత్త
ముఖ్యంగా మీకు కాలేయ వ్యాధి ఉంటే లేదా గతంలో ఉంటే జాగ్రత్తగా తీసుకోవాలి. మీ వైద్య పరిస్థితి మరియు చికిత్సకు మీ ప్రతిస్పందన ఆధారంగా మీ వైద్యుడు మోతాదును మార్చవలసి ఉంటుంది.
కిడ్నీ
అసురక్షిత
దీర్ఘకాలిక మూత్రపిండ వ్యాధి (తీవ్రమైన మూత్రపిండాల బలహీనత) ఉన్న రోగులకు సిఫార్సు చేయబడలేదు. తీవ్రమైన మూత్రపిండాల బలహీనత ఉన్న రోగులలో భద్రత మరియు ప్రభావం స్థాపించబడలేదు.
పిల్లలు
జాగ్రత్త
18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్న పిల్లలలో లోసా-H 50mg/12.5mg టాబ్లెట్ అధ్యయనం చేయబడలేదు. కాబట్టి, ఇది 18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్నవారిలో ఉపయోగించకూడదు.
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