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Neosporin H Ear Drops 5ml is primarily used to treat bacterial ear infections. It can also be used to treat ear infections as a complication after ear surgery (e.g., mastoidectomy, fenestration). It kills bacteria or prevents their growth. It reduces redness, irritation, and discomfort caused by certain ear problems. It may cause common side effects, such as a burning sensation, irritation, itching and redness at the application site.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

HYDROCORTISONE-10MG+NEOMYCIN-3400IU+POLYMYXIN B-10000IU

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

Ear

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Neosporin H Ear Drops 5ml

Neosporin H Ear Drops 5ml is a prescription ear drop used to treat bacterial infections of the outer ear canal, commonly known as swimmer's ear. It works by targeting the bacteria causing the infection while reducing the painful swelling and redness in the ear. This dual action helps relieve discomfort and prevents the infection from spreading deeper.

For the best results, you must use Neosporin H Ear Drops 5ml consistently and exactly as directed by your doctor, usually multiple times throughout the day. It is highly recommended to complete the full course of treatment even if your symptoms improve after a few days. Keeping your ears completely dry and clean during treatment will help the medicine work more effectively.

While most people tolerate these ear drops well, you may experience mild local side effects like temporary burning or stinging. If you notice signs of a severe allergic reaction, worsening hearing issues, or intense skin irritation, stop using the drops and contact your doctor immediately.

Do not use this medicine if you have a torn or ruptured eardrum or if you have a viral or fungal infection in your ear. Talk to your doctor before starting Neosporin H Ear Drops 5ml if you have any chronic ear conditions or a history of hearing issues. Children (especially under 2 years of age) should use this medicine only under strict medical supervision, as dosing and safety require careful evaluation by a doctor.

Inform your doctor about all other ear medications you are using, as some drops may interact with Neosporin H Ear Drops 5ml. If you are pregnant, breastfeeding, or managing health conditions in elderly family members, consult your healthcare provider before application.

Uses of Neosporin H Ear Drops 5ml

Neosporin H Ear Drops 5ml is used in the treatment of bacterial ear infections. The detailed uses of Neosporin H Ear Drops 5ml are as follows:

  • Outer ear infections (Otitis externa): Neosporin H Ear Drops 5ml helps clear painful bacterial infections in the outer ear canal by stopping bacterial growth and calming local tissue inflammation.
  • Ear canal inflammation: It reduces intense itching, redness, and swelling associated with ear canal irritation.

Key Benefits

Neosporin H Ear Drops 5ml helps treat bacterial infections of the outer ear while providing rapid relief from throbbing pain and pressure in the ear.

Benefits may include:

  • Helps treat bacterial infections of the outer ear.
  • Reduces ear pain, swelling, redness, and irritation.
  • Improves comfort by relieving inflammation in the ear canal.
  • Supports faster healing of the infected ear.
  • Helps restore normal hearing and prevent the infection from worsening or spreading.

Directions for Use

  • Wash your hands thoroughly with soap and water before handling the bottle.
  • Lie down on your side or tilt your head so that the infected ear faces upward.
  • Gently pull your earlobe up and back (for adults) or down and back (for children) to straighten the ear canal.
  • Hold the dropper over your ear and squeeze the exact number of drops prescribed by your doctor. Do not let the dropper tip touch your ear, fingers, or any other surface.
  • Stay in this position for about 5 minutes to let the drops sink deep into the ear canal.
  • Always follow your doctor's exact instructions regarding how many drops to use and how long to continue the treatment.

How Neosporin H Ear Drops 5ml Works

Neosporin H Ear Drops 5ml works through the combined power of three distinct active components that target the infection from different angles. • Polymyxin B: It is an antibiotic that attaches to the outer protective cover of the bacteria, disrupting their structure and causing the bacterial cell to break open. • Neomycin: It is an antibiotic that penetrates deep inside the bacterial cells to block them from creating the essential proteins they need to survive and multiply. • Hydrocortisone: It is a steroid that works directly within the ear tissue to limit the production of natural chemicals that cause redness, intense itching, and swelling.
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Alcohol

Caution

No interaction was found/established. However, It is best to avoid alcohol consumption while using medication.

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Pregnancy

Caution

If you are planning to become pregnant or are already pregnant, please inform your doctor. Your doctor will prescribe if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding. Your doctor will prescribe if the benefits outweigh the risks.

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Driving

Safe if prescribed

Neosporin H Ear Drops 5ml has no or negligible influence on the ability to drive or use machines.

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Liver

Caution

Limited information about the usage of Neosporin H Ear Drops 5ml in patients with liver disease is available. Please inform your physician if you have had a liver impairment/disorder history. Your doctor will prescribe if the benefits outweigh the risks.

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Kidney

Caution

Limited information about the usage of Neosporin H Ear Drops 5ml in patients with kidney disease is available. Please inform your physician if you have had a kidney impairment/disorder history. Your doctor will prescribe if the benefits outweigh the risks.

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Children

Caution

Neosporin H Ear Drops 5ml should not be used in children unless prescribed by the doctor.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Neosporin H Ear Drops 5ml in elderly patients. Please consult your doctor.

What if I have taken an overdose of Neosporin H Ear Drops 5ml

This medication is strictly for use in the ears. If someone accidentally swallows the solution or if a large excess is applied, seek immediate medical attention or contact a poison control center right away.

Diet & Lifestyle Advise

  • Keep your ears dry: Keep your ears completely dry throughout your treatment. Wear a well-fitting earplug or place a clean cotton ball coated with a thin layer of petroleum jelly in the outer ear while showering or bathing.
  • Avoid water activities: Do not swim, dive, or take part in water sports until your doctor confirms that the infection has fully cleared.
  • Do not insert objects: Avoid using cotton swabs, hairpins, or other objects inside your ear, as they can push the infection deeper or damage your eardrum.
  • Clean the outer ear gently: Wipe only the outside of your ear with a soft, clean, damp cloth to remove any drainage and keep the area clean.

Health Queries

My daughter have nose bleed problem due to cut on nose doctor suggest neosporin H bt it is not available what will be the subsitute of it

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

Neosporin H is a prescription medicine, and in India, it is available through Apollo’s online pharmacy, where you can place an order by submitting a valid prescription; if your location is serviceable and stock is available at the time you place the order, it will be delivered, and if not, you should check back with your doctor for suitable alterations. Do not attempt to switch on your own, even if other products appear to have the same components, as they may differ in dose strength or release patterns.

I am experiencing continuous itching in my ears, despite being clean. What could be the cause?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Persistent ear itching despite cleanliness can be due to dryness, allergies, a mild fungal infection, or skin conditions such as eczema. Avoid using earbuds or cotton swabs, and consult a doctor if itching continues to identify the exact cause and treat it properly.

I have a dry and itchy ear canal. What can I apply other than Neosporin-H?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

A dry, itchy ear canal can be soothed by keeping the ear clean and dry, avoiding cotton buds, and avoiding scratching. If itching persists, a doctor can suggest a suitable soothing or anti-inflammatory ear preparation based on the cause.

My internal ear is itching and feels dry. What should I do?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Itching in the ear with dryness is often due to irritation, dryness, or a mild allergy, so avoid inserting anything into the ear and keep it dry. If itching persists or if pain or discharge appears, consult a doctor to rule out infection and receive proper treatment.

What can I do if water is trapped in my ear for 3-4 hours?

Dr. S Aneela

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

You can tilt your head to the side and gently pull your earlobe in different directions to help the water drain out. You may also lie on your side with the affected ear facing down, or use a hairdryer on a low setting held at a safe distance to help evaporate the water. Avoid inserting cotton buds or other objects. If the water does not come out, or if you develop pain, hearing loss, or discharge, please see an ENT doctor.
health query

Have a query?

How Soon It Starts Working

  • The time required for Neosporin H Ear Drops 5ml to start to work: The time required for Neosporin H Ear Drops 5ml to show its action is not clinically established.
  • The time for which the effects of Neosporin H Ear Drops 5ml last: The duration of action for Neosporin H Ear Drops 5ml is not clinically established.

What if you forget to take Neosporin H Ear Drops 5ml

If you miss a dose of Neosporin H Ear Drops 5ml, put the drops in as soon as you remember. If it is almost time for your next scheduled application, skip the missed dose and return to your regular schedule. Do not use double the amount of drops to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check the solution before use: Inspect the ear drops before each use. Do not use them if the liquid looks cloudy, has changed colour, or contains floating particles.
  • Keep the dropper clean: Do not let the dropper tip touch your ear, fingers, or any other surface. This helps keep the medicine free from germs.
  • Do not use if your eardrum is damaged: Do not use these ear drops if you think you have a ruptured or perforated eardrum unless your doctor tells you to. Using them in this situation may cause serious ear damage.
  • Use only for the prescribed duration: Do not use these ear drops for longer than your doctor recommends. Prolonged use may increase the risk of a fungal ear infection.
  • For the ears only: Use this medicine only in your ears. Do not put it in your eyes, nose, or mouth.

Drug-Drug Interactions

verifiedApollotooltip
  • Other Ear Medications (e.g., ciprofloxacin, acetic acid, clotrimazole): Avoid using other antibiotic or antifungal ear drops at the same time as Neosporin H Ear Drops 5ml unless specifically advised by your doctor, as they can interfere with how this medicine is absorbed.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food or drink interactions are known with Neosporin H Ear Drops 5ml when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

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Therapeutic Class

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FAQs

Neosporin H Ear Drops 5ml is used to treat ear infections caused by bacteria.
Neosporin H Ear Drops 5ml is a combination medicine that contains Neomycin, Polymyxin B and Hydrocortisone. Neomycin and polymyxin B belong to the class of medicines known as antibiotics; they work by killing bacteria or preventing their growth. Hydrocortisone is a steroid medicine used to relieve the redness, itching, and swelling caused by ear infections. Together, Neosporin H Ear Drops 5ml reduces redness, irritation, and discomfort of certain ear problems.
Neosporin H Ear Drops 5ml should not be used for longer durations unless prescribed by a doctor. If your condition does not improve despite using Neosporin H Ear Drops 5ml for 2-4 weeks, consult your doctor.
Neosporin H Ear Drops 5ml does not help in treating eye infections. Neosporin H Ear Drops 5ml is used to treat ear infections caused by bacteria.
Please do not stop using Neosporin H Ear Drops 5ml without consulting your doctor on your own. Continue using Neosporin H Ear Drops 5ml for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Neosporin H Ear Drops 5ml.
Neosporin H Ear Drops 5ml starts working immediately; however, it might take a few days to kill the harmful bacteria. Complete the course of treatment to treat your condition effectively.
Lie down with the affected ear facing upwards. Hold the dropper over the ear and instil the prescribed number of drops. Continue to lie on your side for two minutes to allow the drops to reach the base of the ear canal.
Neosporin H Ear Drops 5ml can be used during pregnancy or breastfeeding if advised by the doctor. Please consult the doctor if you are pregnant or breastfeeding.
Neosporin H Ear Drops 5ml is for otic (ear) use only. Avoid touching the tip of the dropper as it may contaminate the contents. Do not swim or shower immediately immediately after using Neosporin H Ear Drops 5ml.
Neosporin H Ear Drops 5ml may cause side effects such as a burning sensation, irritation, itching and redness at the application site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Store Neosporin H Ear Drops 5ml at room temperature, in a dry place. Keep it out of sight and reach of children.
No, you should not use Neosporin H Ear Drops 5ml if you have a torn or ruptured eardrum. Applying these drops through a damaged eardrum can cause serious pain and potential hearing damage. Talk to your doctor to find a safer alternative.
You should keep your head tilted or lie on your side for about 5 minutes after putting the drops in. This allows the medicine to flow deep into your ear canal and absorb properly. Talk to your doctor if you find this difficult.
If the drops accidentally get into your eyes, rinse them immediately and thoroughly with plenty of cool, clean water. If you experience persistent burning, redness, or changes in your vision, contact an eye doctor or seek medical help right away.
It is generally best to avoid wearing hearing aids, earplugs, or headphones while your ear infection is active and while you are using Neosporin H Ear Drops 5ml. These devices can trap moisture and bacteria, slowing down your recovery. Talk to your doctor for personalised advice.
No, you should avoid swimming, diving, and getting water inside your ear while treating an infection. Water can introduce new bacteria and wash away the medication, delaying your healing. Talk to your doctor to know when it is safe to swim again.
Instil the missed drops into your ear as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed application and continue with your regular schedule. Do not double the dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. MedlinePlus. A618031 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Hydrocortisone Neomycin And Polymyxin B Otic Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Polymyxin B, neomycin, and hydrocortisone. [Accessed on 20 Feb 2026]Check here
  4. Casper Pharma LLC. Polymyxin B, Neomycin and Hydrocortisone. [Revised in December 2017] [Accessed on 13th July 2022] docs/label/2017/060613s013lbl.pdfCheck here
  5. RPK Pharmaceuticals, Inc. Polymyxin B, Neomycin and Hydrocortisone. [Revised in December 2020] [Accessed on 13th July 2022]Check here
  6. Proficient Rx LP. Polymyxin B, Neomycin and Hydrocortisone. [Revised in April 2019] [Accessed on 13th July 2022]Check here
  7. Neomycin And Polymyxinb Sulfates And Hydrocortisone Otic Solution. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

Stiefel India Ltd., 401& 402, A Wing, IV Floor, Floral Deck Plaza, Opp. Rolta Bhavan, Central MIDC Road, Andheri (East), Mumbai – 400093
Other Info - NEO0021
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