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Silverex SSD Cream is used to treat burns and prevent skin infections. It contains Silver sulfadiazine and Chlorhexidine, which inhibit the production of folic acid (a vitamin) necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Also, it works by binding to the skin strongly and kills micro-organisms on the skin and prevents infection. In some cases, you may experience irritation, itching, or burning sensation at the site of application.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Silverex SSD Cream

Silverex SSD Cream is a topical cream prescribed primarily to prevent and treat infections in people with second- and third-degree burn wounds. By keeping the wound clean and free of bacteria, it plays a vital role in preventing serious skin infections and supporting the body's natural recovery process. It is also used to protect skin graft areas and chronic ulcers from bacterial contamination.

For the best results, Silverex SSD Cream must be applied consistently as directed by your healthcare professional, usually once or twice every day. Since this is a topical cream applied directly to the skin, it does not need to be timed around your meals. To help your skin recover more effectively, it is highly recommended to follow a protein-rich diet and stay hydrated, as these lifestyle choices provide the building blocks your body needs to rebuild skin tissue.

While Silverex SSD Cream is highly effective, some people may experience mild side effects, such as temporary skin itching, burning, or a grayish discolouration of the skin. If you notice any signs of a severe allergic reaction, such as a severe skin rash, breathing difficulties, or swelling of your face, you must stop using the cream and seek immediate medical care. Always consult your doctor or pharmacist if you experience any unexpected or worsening skin symptoms.

Before you begin using Silverex SSD Cream, tell your doctor if you have certain health conditions, especially liver or kidney disease, or a genetic condition known as G6PD deficiency. Do not use this cream if you are treating a premature infant or a newborn in their first few months of life, as their bodies cannot process the ingredients safely. It should also be avoided in the late stages of pregnancy.

This cream may interact with other topical products or certain oral medicines, so always inform your healthcare provider about everything you are applying to your skin or taking by mouth. If you are pregnant, breastfeeding, or caring for an elderly patient, talk to your doctor or pharmacist to ensure Silverex SSD Cream is the safest option for your specific situation.

Description

Silverex SSD Cream is a powerful combination of chlorhexidine gluconate and silver sulfadiazine. It acts as an antiseptic and disinfectant, killing infectious microorganisms and keeping cuts, wounds, and burns clean to prevent infection. The antibiotic properties of silver sulfadiazine stop bacteria from multiplying by hindering the production of folic acid. This cream is reliable for effectively treating various skin infections and preventing their spread. Beyond infection prevention, Silverex SSD actively supports healing, making it a comprehensive solution.



Features

  • Antiseptic and Disinfectant
  • Targeted Microbial Control
  • Provides comprehensive burn care with faster healing
  • User-Friendly External Application
  • Travel-friendly

Uses of Silverex SSD Cream

Silverex SSD Cream is used to prevent and treat bacterial infections in damaged skin and wounds. It is commonly applied to burns, ulcers, and graft sites where infection control is essential for proper healing, including:

  • Burn wound infections: Silverex SSD Cream helps prevent and treat bacterial growth in second- and third-degree burns, keeping the wound clean and sterile.
  • Skin graft protection: It protects newly grafted skin areas from environmental bacteria, reducing the risk of graft rejection due to local infection.
  • Chronic ulcer treatment: It is used to clear bacterial infections in long-term skin sores, such as pressure wounds or diabetic leg ulcers.

Key Benefits

By combining two powerful antimicrobial agents, Silverex SSD Cream provides several benefits that support wound healing and infection prevention, including:

  • Broad-Spectrum Infection Protection: Helps control a wide range of bacteria that commonly infect burns and open wounds.
  • Reduces the Risk of Serious Complications: Prevents local wound infections from progressing into more severe or systemic infections.
  • Supports Wound Healing: Maintains a cleaner wound environment, allowing the body's natural healing processes to work more effectively.
  • Protects Vulnerable Skin Areas: Provides ongoing antimicrobial protection for burns, skin grafts, and chronic ulcers.
  • Helps Maintain a Moist Healing Environment: The cream base helps keep wounds appropriately moisturised, which can support tissue repair.
  • Improves Comfort During Recovery: Forms a protective barrier over damaged skin, helping reduce irritation from external contaminants and dressing changes.
Side effects of Silverex SSD Cream 20 gm
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce irritation.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin soothing.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Recognise the signs of skin necrosis and seek early diagnosis for prompt action.
  • Clean wounds thoroughly and change dressings regularly for optimal healing.
  • Apply topical creams or gels to aid wound healing.
  • Use pressure-reducing measures to prevent skin necrosis ulcers.
  • Maintain a balanced diet and stay hydrated to support healing.
  • Quit smoking to help in faster healing.
  • Follow your doctor's instructions carefully for effective skin necrosis management.
  • Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Keep yourself hydrated or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Apply a small amount of Silverex SSD Cream on the clean and dry affected area with the help of an applicator or a clean cotton ball, or a swab as directed by the doctor.
  • Silverex SSD Cream is for external use only.
  • Avoid contact of Silverex SSD Cream with nose, mouth or eyes. If contact occurs, rinse with water.

How Silverex SSD Cream Works

Silverex SSD Cream contains two active medicines that work together to prevent and treat skin infections in wounds and burns. Silver sulfadiazine is an antibacterial medicine that works by slowly releasing silver ions into the affected area. These silver ions damage bacterial cells and interfere with their growth and multiplication, helping to control and eliminate infection. Chlorhexidine gluconate is an antiseptic agent that works by disrupting the outer membrane of bacteria. This causes the bacterial cells to leak their contents and die, helping to reduce the number of harmful microorganisms on the skin and wound surface. Together, these medicines help prevent infection, keep wounds clean, reduce bacterial growth, and support the natural healing process of the skin.
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Alcohol

Caution

The interaction of Silverex SSD Cream with alcohol is unknown. Please consult a doctor before consuming alcohol while using Silverex SSD Cream.

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Pregnancy

Unsafe

Silverex SSD Cream is a category B pregnancy drug and is usually not recommended for pregnant women as it may cause adverse effects in the new-born. However, please consult a doctor if you are pregnant before using Silverex SSD Cream.

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Breast Feeding

Caution

Silverex SSD Cream may be excreted in human milk and cause harm to the baby. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Silverex SSD Cream usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Silverex SSD Cream in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Silverex SSD Cream in patients with kidney problems, please consult a doctor.

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Children

Caution

Silverex SSD Cream is not recommended for babies below 2 months of age as it may cause severe irritation. However, Silverex SSD Cream should be used with caution in children above 2 months if prescribed by a doctor.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Silverex SSD Cream in elderly patients. Please consult your doctor.

What if I have taken an overdose of Silverex SSD Cream

Because Silverex SSD Cream is applied to the skin, an accidental overdose from normal topical use is rare. However, if the cream is swallowed, or if it is applied excessively over massive areas of the body and you feel unwell, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Eat a protein-rich diet: Include lean meats, fish, eggs, dairy, beans, or tofu in your daily meals to provide the amino acids your body needs for skin repair.
  • Stay hydrated: Drink plenty of water throughout the day. Healing wounds require proper skin hydration to recover efficiently.
  • Increase Vitamin C and Zinc: Eat foods like bell peppers, citrus fruits, nuts, and seeds, which are clinically known to support collagen production and immune health.
  • Avoid smoking: Tobacco smoke constricts blood vessels, reducing the delivery of oxygen and vital nutrients to your healing skin, which can significantly delay recovery.
health query

Have a query?

How Soon It Starts Working

The time required for Silverex SSD Cream to start to work: The time required for Silverex SSD Cream to show its action is not clinically established. The time for which the effects of Silverex SSD Cream last: The duration of action for Silverex SSD Cream is not clinically established.

What if you forget to take Silverex SSD Cream

If you realise you have missed an application, apply Silverex SSD Cream as soon as possible. However, if it is almost time for your next scheduled application, skip the missed dose and return to your regular routine. Do not apply a double layer of cream to make up for a missed application.

Storage

•Store Silverex SSD Cream at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the container tightly closed when not in use to protect the cream from contamination.

Drug Warnings

  • Check the colour: Always inspect the cream before applying. If it has turned dark gray, black, or has separated, do not use it and consult your pharmacist.
  • Use sterile tools: Never dip your bare fingers directly into the jar if you are not wearing sterile gloves. Use a sterile applicator to avoid introducing bacteria into the container.
  • Protect treated areas from the sun: This medicine can make your skin more sensitive to sunlight, which may cause dark skin staining. Keep treated areas shaded or covered when outdoors.
  • Limit use on large areas: If you are applying the cream to a very large part of your body, talk to your doctor regularly to monitor your blood counts and kidney function.
  • Avoid contact with clothing: The cream can cause gray or silver staining on fabrics, so cover the application site with sterile dressings if needed to protect your clothes.

Drug-Drug Interactions

verifiedApollotooltip

Silverex SSD Cream may interact with certain medicines applied to wounds or absorbed into the body, potentially affecting treatment effectiveness or increasing the risk of side effects, including:

  • Topical enzymatic debriding agents (like collagenase): Silverex SSD Cream can deactivate these enzymes, preventing them from clearing away dead skin tissue. Do not use them together on the same wound.
  • Oral sulfonamide medicines: Combining this topical cream with oral sulfa drugs may increase the risk of systemic side effects, such as changes in your blood cell levels.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Silverex SSD Cream when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS- TOPICAL ANTIBIOTICS/ANTIMICROBIALS]

FAQs

Apply Silverex Cream one to two times a day or as directed by your doctor. Consistent use as directed ensures the cream's effectiveness in managing burn injuries.
Results may vary according to individual, but consistent use is recommended. Consult your doctor if your condition doesn't improve or worsens.
Yes, Silverex Cream is designed for burn injuries and is effective in addressing various degrees of burns. Consult your doctor for specific guidance.
There are no specific studies conducted on the safety of Silverex SSD Cream during pregnancy or while breastfeeding. It is advisable to consult a healthcare professional before using the cream in such cases.
Silverex SSD Cream is used to treat burns and prevent skin infections.
Silverex SSD Cream contains Silver sulfadiazine and Chlorhexidine. Silver sulfadiazine is an antibiotic that works by inhibiting the production of folic acid (a vitamin) that is necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Chlorhexidine is an antiseptic that works by binding to the skin strongly and kills micro-organisms on the skin. Together, Silverex SSD Cream helps to clean the skin and prevent infection.
Yes, Silverex SSD Cream may cause itching of the skin at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.
You are not recommended to use Silverex SSD Cream with prilocaine (local anaesthetic) as it may increase the risk of methemoglobinemia (a blood disorder in which very less oxygen is delivered to vital organs and tissues). If you experience shortness of breath, dizziness, rapid heartbeat, anxiety, light-headedness, grey discolouration of the skin, nail bed or mouth, confusion, headache, nausea or tiredness, please consult a doctor immediately. However, consult your doctor before using Silverex SSD Cream with other medicines.
Silverex SSD Cream may cause staining of clothes as it contains Chlorhexidine responsible for staining. Therefore, avoid contact of Silverex SSD Cream with clothes or fabric and also avoid bleach to wash fabric that is in contact with Silverex SSD Cream as it may cause a permanent stain.
You are recommended to use Silverex SSD Cream for as long as your doctor has prescribed it. However, if the condition persists or worsens after using Silverex SSD Cream for 1 week, please consult a doctor.
The common side effects of Silverex SSD Cream are irritation, itching, or burning sensation at the site of application. If any of these side effects persist or worsen, please consult your doctor.
Silverex SSD Cream is designed specifically for moderate to severe burns, skin grafts, and specific chronic ulcers. For minor everyday cuts or scrapes, ask your doctor or pharmacist to recommend a standard first-aid antiseptic cream instead.
If the cream in your container has turned dark gray or black, it may have lost its effectiveness due to exposure to light or heat. Do not apply it; bring it to your pharmacist for advice or a replacement.
You should avoid using Silverex SSD Cream during the late stages of pregnancy (near the due date) as it may cause complications for the newborn. Always talk to your doctor to weigh the benefits and risks if you are pregnant.
Yes, you can cover the area with sterile gauze dressings as directed by your doctor. However, ensure that a continuous layer of the cream remains on the wound, and reapply it if the dressing absorbs the cream.
Silverex SSD Cream starts working immediately to prevent bacterial growth. The overall healing time of your skin depends on the size and severity of your wound. Talk to your doctor to monitor your progress.
Do not use Silverex SSD Cream on premature infants or newborns during their first two months of life, as their organs are not mature enough to process the absorbed ingredients safely. Talk to your doctor for safer alternatives.
The cream may cause a temporary grey or brownish discolouration of the skin at the application site. This staining usually fades after you stop using the medicine and the skin fully heals. Talk to your doctor if you have concerns.
You should avoid mixing or layering other topical creams, ointments, or skin cleansers with Silverex SSD Cream unless your doctor explicitly tells you to do so, as they may interfere with how this medicine works.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - SIL0581
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