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Valium 10Mg Tablet is used to treat short-term relief of severe anxiety disorder, muscle spasms and fits (seizures). Besides this, it also reduces alcohol withdrawal symptoms (like sweating or difficulty sleeping etc.). Before undergoing any surgical procedure, it is sometimes given as pre-med to prevent anxiety, fear and worry. It contains Diazepam, which works by increasing levels of calming chemical, known as gamma-aminobutyric acid (GABA), in your brain that helps to relieve anxiety and stop seizures attacks (fits), and relaxes the tense muscles. Besides this, it relieves temporary insomnia (sleeplessness) due to anxiety disorder. Off-label uses include alcohol withdrawal syndrome, insomnia, panic disorder, chemotherapy-associated nausea and vomiting. Sometimes, you may experience certain common side effects, such as daytime drowsiness, light-headedness, unsteadiness, or dizziness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Valium 10Mg Tablet
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

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Drug-Drug Interactions

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Drug-Drug Interactions: Valium 10Mg Tablet may have interacted with antianxiety or antiepileptic medicines (e.g. carbamazepine, fluvoxamine, phenobarbital, phenytoin, primidone), anti-HIV drugs (e.g. amprenavir, ritonavir), acidity medicine (e.g. cimetidine), pills to treat chronic alcoholism (e.g. disulfiram), antibiotics (e.g. rifampicin), anti-Parkinson’s drug (e.g. levodopa), and asthma drugs (e.g. theophylline). Besides this, central nervous system depressant drugs and opioid analgesics or pain killers should be avoided with Valium 10Mg Tablet as they may cause life-threatening conditions.

Drug-Food Interactions: Grapefruit, grapefruit juice and caffeine-containing food or drinks should be avoided as they can affect the working of Valium 10Mg Tablet .

Drug-Disease Interactions: Valium 10Mg Tablet may interact with disease conditions, including obesity, acute alcohol intoxication, closed-angle glaucoma, drug addiction, kidney/liver disease, respiratory depression, prolonged low blood pressure, muscle disease (myasthenia gravis), and severe seizures (fits).

DiazepamSufentanil
Severe
DiazepamEsketamine
Severe

Drug-Drug Interactions

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DiazepamSufentanil
Severe
How does the drug interact with Valium 10Mg Tablet:
Co-administration of Sufentanil with Valium 10Mg Tablet can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Valium 10Mg Tablet with Sufentanil can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DiazepamEsketamine
Severe
How does the drug interact with Valium 10Mg Tablet:
Co-administration of Valium 10Mg Tablet with esketamine may increase side effects such as confusion, drowsiness, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although there is a possible interaction, Valium 10Mg Tablet should be taken with esketamine if prescribed by the doctor. However, avoid driving or operating heavy machinery after treatment with esketamine as you may experience drowsiness. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Valium 10Mg Tablet:
Co-administration of Valium 10Mg Tablet with Ketamine can increase the risk of CNS depression.

How to manage the interaction:
Taking Ketamine with Valium 10Mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
DiazepamDroperidol
Severe
How does the drug interact with Valium 10Mg Tablet:
Taking Droperidol can enhance the sedative effects of Valium 10Mg Tablet causing excessively slow heart rate and low blood pressure, and using it with Valium 10Mg Tablet may increase those risks.

How to manage the interaction:
Taking Valium 10Mg Tablet with Droperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - a very slow heart rate, low blood pressure, an irregular heartbeat, sudden dizziness, feeling lightheaded, fainting, or a strange heartbeat - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
DiazepamEthanol
Severe
How does the drug interact with Valium 10Mg Tablet:
Drinking alcohol while taking Valium 10Mg Tablet can make you feel more sleepy and slow down your brain and body.

How to manage the interaction:
Although there is a possible interaction between Ethanol and Valium 10Mg Tablet, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - problems with your brain or nerves, feeling dizzy, feeling sleepy or having trouble focusing - make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DiazepamMethadone
Severe
How does the drug interact with Valium 10Mg Tablet:
Taking of Valium 10Mg Tablet with methadone may cause serious side effects like respiratory distress.

How to manage the interaction:
Although there is a possible interaction, Valium 10Mg Tablet should be taken with methadone only if prescribed by the doctor. The doctor may prescribe alternatives that do not interact, dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Valium 10Mg Tablet:
Co-administration of Tapentadol together with Valium 10Mg Tablet can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Valium 10Mg Tablet with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
DiazepamRemifentanil
Severe
How does the drug interact with Valium 10Mg Tablet:
Co-administration of Remifentanil with Valium 10Mg Tablet can increase the seriousness of side effects.

How to manage the interaction:
Although taking Valium 10Mg Tablet and Remifentanil together can evidently cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your health and talk to your doctor about any concerns. They can recommend different options that won't cause any problems. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valium 10Mg Tablet:
Taking Valium 10Mg Tablet together with fluvoxamine may cause an increase in side effects such as drowsiness, confusion, muscle weakness, and fainting.

How to manage the interaction:
Although there is a possible interaction, Valium 10Mg Tablet can be taken with fluvoxamine if prescribed by the doctor. However, if you experience any unusual symptoms consult your doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valium 10Mg Tablet:
Taking Valium 10Mg Tablet and fentanyl together can increase the risk of side effects.

How to manage the interaction:
Although taking Fentanyl together with Valium 10Mg Tablet can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you have sleepiness, difficulty concentrating, and impaired judgment. Do not stop taking any medication without consulting your doctor.

Drug-Food Interactions

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DIAZEPAM-10MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DIAZEPAM-10MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit

How to manage the interaction:
Grapefruit and grapefruit juice may interact with Valium 10Mg Tablet leading to potentially dangerous side effects. Avoid increasing or decreasing the amount of grapefruit products in your diet without talking to a doctor.

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