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Caldezone Plus Softgel Capsule 10's is used to treat, improve, control, and prevent various complications or long-term diseases. It is used to treat anaemia, respiratory illnesses, brain and spinal cord disorders, heart diseases, kidney diseases, skin problems, hormonal disorders, and immune system problems. It protects the nerves from damage and promotes the production of blood cells. It helps in building strong bones and improves learning abilities, especially in children. Additionally, it reduces excess cholesterol levels in the body, thereby maintaining the health of the heart, brain, and nerves. It may cause side effects such as nausea (feeling sick), vomiting (being sick), diarrhoea, anorexia (loss of appetite), headache, weight loss, fatigue, bloating, and flatulence.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

About Caldezone Plus Softgel Capsule 10's

Caldezone Plus Softgel Capsule 10's is a comprehensive oral nutritional supplement formulated to support bone density, joint flexibility, and healthy nerve function. It is commonly prescribed to manage conditions like osteoporosis, joint pain, and nerve damage caused by nutritional deficiencies. By supplying a combination of essential minerals, vitamins, and fatty acids, this medication helps maintain your body's structural integrity and neurological health.

For the best results, you should take Caldezone Plus Softgel Capsule 10's consistently at the same time every day. It is highly recommended to take this capsule with a meal, as dietary fats help your body absorb the active ingredients more efficiently. Combining this supplement with a balanced diet and regular weight-bearing physical activity can significantly improve your long-term bone and joint health.

While taking Caldezone Plus Softgel Capsule 10's, some people may experience mild, temporary side effects such as mild stomach upset or constipation. However, if you experience persistent symptoms or signs of high calcium levels, such as extreme thirst, muscle weakness, or confusion, stop taking the medication and consult your doctor immediately.

Talk to your doctor or pharmacist before starting Caldezone Plus Softgel Capsule 10's if you have pre-existing kidney conditions, a history of kidney stones, or high levels of calcium in your blood or urine. Do not take this medication if you have been diagnosed with hypercalcemia (excessive calcium in the blood) or are allergic to any of the ingredients in this formulation.

Certain medications, including thyroid treatments, specific antibiotics, and blood thinners, can interact with Caldezone Plus Softgel Capsule 10's, making them less effective or increasing the risk of side effects. If you are pregnant, planning a pregnancy, breastfeeding, or are an elderly individual, consult your healthcare provider to ensure this supplement is safe and appropriate for your specific needs.

Uses of Caldezone Plus Softgel Capsule 10's

Caldezone Plus Softgel Capsule 10's is used in the treatment and management of nutritional deficiencies. The detailed uses of Caldezone Plus Softgel Capsule 10's are as follows:

  • Nutritional Deficiencies: Replenishes vital nutrients when your dietary intake is insufficient to meet your body's physical demands.
  • Osteoporosis and Bone Weakness: Helps rebuild and maintain strong bone mineral density, reducing the risk of fractures.
  • Neuropathy and Nerve Discomfort: Supports the recovery of damaged nerve cells and helps ease tingling, numbness, and burning sensations.
  • Joint Support: Promotes cartilage health and helps manage inflammation in the joints for smoother movement.
     

Key Benefits

Caldezone Plus Softgel Capsule 10's helps support bone strength, nerve health, and overall physical well-being by providing a combination of essential vitamins, minerals, and nutrients. It promotes healthy mobility, supports recovery, and helps maintain an active lifestyle. Benefits may include:

• Supports strong and healthy bones by improving calcium absorption and utilisation.
• Helps reduce the risk of bone weakness and supports bone health during ageing.
• Supports healthy nerve function and helps maintain nerve cell health.
• Promotes nerve repair and helps maintain the protective covering around nerves.
• Supports healthy red blood cell production and overall tissue repair.
• Helps support joint comfort, mobility, and overall physical well-being.

Directions for Use

  • Take Caldezone Plus Softgel Capsule 10's with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Caldezone Plus Softgel Capsule 10's Works

Caldezone Plus Softgel Capsule 10's contains Calcitriol, Calcium Carbonate, Methylcobalamin, Folic Acid, Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid (EPA), and Boron. • Calcitriol: It is the active form of vitamin D3 that helps the body absorb calcium efficiently from food and supplements, supporting strong bones and teeth. • Calcium Carbonate: It provides calcium, an essential mineral needed to build and maintain healthy bones and teeth. It also supports normal muscle and nerve function. • Methylcobalamin: It is an active form of vitamin B12 that helps nourish and repair nerve cells, supporting healthy nerve function and overall neurological health. • Folic Acid: It helps the body produce healthy red blood cells and supports normal cell growth, repair, and overall health. • Docosahexaenoic Acid (DHA): It is an omega-3 fatty acid that helps support brain, eye, heart, and joint health. • Eicosapentaenoic Acid (EPA): It is an omega-3 fatty acid that helps support joint comfort and overall cardiovascular health while helping maintain a healthy inflammatory response. • Boron: It is a trace mineral that helps support bone health and assists the body in making effective use of important minerals such as calcium, magnesium, and phosphorus.
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Alcohol

Caution

Alcohol may increase the risk of side-effects, so do not consume alcohol.

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Pregnancy

Consult your doctor

There are no sufficient data available to establish the safe use of Caldezone Plus Softgel Capsule 10's during pregnancy, so consult a doctor before using Caldezone Plus Softgel Capsule 10's.

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Breast Feeding

Consult your doctor

There are no sufficient data available to establish the safe use of Caldezone Plus Softgel Capsule 10's in breastfeeding mothers, so consult a doctor before using Caldezone Plus Softgel Capsule 10's.

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Driving

Safe if prescribed

Caldezone Plus Softgel Capsule 10's may not affect your ability to drive.

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Liver

Safe if prescribed

Caldezone Plus Softgel Capsule 10's may be possibly safe when prescribed in patients with liver diseases.

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Kidney

Caution

Caldezone Plus Softgel Capsule 10's should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

There is limited data available to establish the safe use of Caldezone Plus Softgel Capsule 10's in children, so talk to your doctor before using Caldezone Plus Softgel Capsule 10's.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Caldezone Plus Softgel Capsule 10's in elderly patients. Please consult your doctor.

What if I have taken an overdose of Caldezone Plus Softgel Capsule 10's

If you suspect an overdose, seek immediate medical attention or contact a local poison control center. Symptoms of an overdose may include severe nausea, vomiting, confusion, extreme muscle weakness, or a sudden change in urination patterns.

Diet & Lifestyle Advise

  • Eat calcium-rich foods: Include foods such as leafy green vegetables, yogurt, milk, and fortified products in your daily diet to help support strong and healthy bones.
  • Engage in weight-bearing exercise: Participate in regular low-impact activities such as brisk walking or light strength training to help maintain bone strength and density.
  • Stay well hydrated: Drink plenty of water throughout the day to support kidney health and help reduce the risk of kidney stone formation.
  • Limit calcium-depleting substances: Reduce your intake of caffeine, alcohol, and carbonated sodas, as they may interfere with calcium absorption and retention in the body.
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How Soon It Starts Working

  • The time required for Caldezone Plus Softgel Capsule 10's to start to work: The time required for Caldezone Plus Softgel Capsule 10's to show its action is unknown.
  • The time for which the effects of Caldezone Plus Softgel Capsule 10's last: The duration of action for Caldezone Plus Softgel Capsule 10's is unknown.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if you forget to take Caldezone Plus Softgel Capsule 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take two doses at the same time to make up for a missed capsule.

Drug Warnings

  • Inspect the medicine before use: Do not take the capsule if it appears cracked, leaking, unusually soft, or otherwise damaged.
  • Separate antacids from your dose: Avoid taking antacids containing aluminum or magnesium within 2 hours of taking Caldezone Plus Softgel Capsule 10's, as they may reduce the absorption of its active ingredients.
  • Inform healthcare providers before procedures: Tell your doctor or dentist that you are taking Caldezone Plus Softgel Capsule 10's before undergoing any surgery or dental procedure, as omega-3 fatty acids may occasionally affect bleeding time.
  • Attend regular monitoring appointments: Keep all scheduled blood tests and kidney check-ups, as your doctor may monitor your calcium levels and overall response to treatment.
  • Follow your treatment plan carefully: Take Caldezone Plus Softgel Capsule 10's exactly as prescribed and attend all follow-up visits to help ensure safe and effective therapy.

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Drug-Drug Interactions

  • Thyroid medications (e.g., levothyroxine): Calcium can significantly lower the absorption of thyroid hormones. Separate these doses by at least 4 hours.
  • Antibiotics (e.g., quinolones and tetracyclines): Calcium reduces the effectiveness of these medications. Take your antibiotic at least 2 hours before or 4 to 6 hours after taking medicine
  • Blood thinners (e.g., warfarin): The omega-3 fatty acids in this supplement may slightly increase the risk of bleeding when taken alongside anticoagulant medications.
  • Thiazide diuretics: Taking these water pills with calcium can decrease calcium excretion, increasing your risk of high blood calcium levels.

Drug-Food Interactions

  • High-fiber foods: Consuming large amounts of bran or whole grains at the same time as your supplement can slightly reduce calcium absorption.
  • Alcohol: Heavy alcohol intake can impair your body's ability to absorb vital minerals and vitamins, making the treatment less effective.

Drug-Disease Interactions

  • Hypercalcemia: Do not take this medication if you currently have high levels of calcium in your blood.
  • Kidney Stones or Kidney Disease: Use with caution, as high intake of calcium and calcitriol can increase the risk of stone formation or place extra strain on compromised kidneys.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Caldezone Plus Softgel Capsule 10's belongs to a class of medications called Nutritional Supplements, used to treat nutritional deficiencies.
Caldezone Plus Softgel Capsule 10's contains Methylcobalamin, Calcitriol, Calcium carbonate, Docosahexaenoic acid (DHA), Boron, Folic acid, and Eicosapentaenoic acid (EPA). Methylcobalamin protects the nerves from damage. Calcitriol helps to promote bone health. Calcium carbonate treats calcium deficiency. Boron helps in building strong bones. Folic Acid is also known as folate or vitamin B9. It helps in producing blood (haemoglobin) in the body. DHA and EPA reduce cholesterol levels in the body and also promote brain health. Together, Caldezone Plus Softgel Capsule 10's effectively provides essential nutrition for nutritional deficiencies due to chronic conditions, surgery, trauma or other complications.
Caldezone Plus Softgel Capsule 10's is possibly safe when used in patients with thyroid problems. However, make sure to inform your doctor before taking this medicine as Caldezone Plus Softgel Capsule 10's may interact with levothyroxine, used to treat hypothyroidism (underactive thyroid).
While using Caldezone Plus Softgel Capsule 10's, do not take any other dietary or herbal supplements containing vitamin D, omega-3 fatty acids, other vitamins or other OTC supplements without discussing with your doctor. Besides this, avoid using foods fortified with vitamin D and high amounts of dairy products.
Caldezone Plus Softgel Capsule 10's can be safely used in patients with diabetes unless you have other problems such as kidney diseases or bone-related problems. So, it is recommended to inform your doctor before taking Caldezone Plus Softgel Capsule 10's to avoid any risks.
Caldezone Plus Softgel Capsule 10's may cause side effects such as nausea (feeling sick), vomiting (being sick), diarrhea, anorexia (loss of appetite), headache, weight loss, fatigue, bloating, and flatulence. These side effects usually do not require any medical attention.
You should take this medicine as prescribed by your doctor. It should be swallowed as a whole with a glass of water. Do not crush, chew, or break it.
Caldezone Plus Softgel Capsule 10's contains Methylcobalamin, Calcitriol, Calcium Carbonate, Docosahexaenoic Acid (DHA), Boron, Folic Acid and Eicosapentaenoic Acid (EPA).
It is highly recommended to take Caldezone Plus Softgel Capsule 10's with food. Having a meal helps your body absorb the fat-soluble vitamins and fatty acids inside the capsule, and also lowers the chances of experiencing an upset stomach. Talk to your doctor if you have concerns
Dizziness is not a common side effect of Caldezone Plus Softgel Capsule 10's. It may happen in rare cases. Usually, it does not require medical attention and fades away with time. If it persists, please consult the doctor.
Nausea and vomiting are common side effects of Caldezone Plus Softgel Capsule 10's. They usually do not require medical attention and fade away with time. If they persist, please consult the doctor.
Store in a cool and dry place away from sunlight. Keep this medicine out of the sight and reach of children.
There is limited data available to establish the safe use of Caldezone Plus Softgel Capsule 10's during pregnancy, so consult a doctor before using Caldezone Plus Softgel Capsule 10's.
There is no sufficient data available to establish the safe use of Caldezone Plus Softgel Capsule 10's in children, so consult a doctor before using Caldezone Plus Softgel Capsule 10's.
A mild metallic taste can occasionally occur while taking nutritional supplements containing vitamins and minerals. If the taste is persistent, worsening, or occurs along with symptoms such as nausea, unusual thirst, fatigue, or muscle weakness, seek medical advice, as further evaluation may be needed.
Alcohol may increase the risk of side effects, so do not consume alcohol.
It is best to avoid taking them at the exact same time. Calcium can interfere with your body's ability to absorb iron. You should separate the intake of these two supplements by at least 2 to 3 hours. Talk to your doctor to set up an ideal daily schedule.
If you have had kidney stones, you must exercise caution. Calcitriol and calcium can increase the amount of calcium excreted in your urine, potentially raising the risk of new stones. Consult to your doctor to determine if this medication is safe for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Methylcobalamin Vitamin B12 Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Docosahexaenoic Acid Dha Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. WebMD Medical Reference Review Board. Eicosapentaenoic Acid Epa Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Electronic Medicines Compendium (EMC). Pil.11802 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Pil.5232 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Drugs.com Clinical Review Team. Boron Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  7. Electronic Medicines Compendium (EMC). Pil.6998 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

#25/24-1 1st Floor, 50 ft Road, T. G. Lauout, ITTamadu, BSK 3rd Stage, Bengaluru-560085
Other Info - CAL3913

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