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Mecofol Plus D3 Tablet 10's

Mecofol Plus D3 Tablet is a combination medicine used in the treatment of neuropathic pain, diabetic neuropathy and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, and stomach upset.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

ALPHA LIPOIC ACID-100MG+FOLIC ACID-1.5MG+METHYLCOBALAMIN-1500MCG+VITAMIN B6-3MG+VITAMIN D3-1000IU

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mecofol Plus D3 Tablet

Mecofol Plus D3 Tablet is used to treat neuropathic pain associated with diabetic neuropathy and nutritional deficiencies. Mecofol Plus D3 Tablet might help enhance blood calcium levels, increase metabolism, facilitate the conversion of glucose into energy, help improve the body’s oxidative stores and develop healthy red blood cells.

Mecofol Plus D3 Tablet consists of Methylcobalamin, Alpha-lipoic acid, Vitamin B6, Vitamin D3, and Folic acid. This combination helps repair and protect damaged nerves, protects the nerves and brain from damage, eases nerve-related problems, improves balance, and provides essential nutrients for healthy nerves.

In some cases, you may experience certain common side effects, such as stomach upset, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Mecofol Plus D3 Tablet if you are pregnant or breastfeeding. Limited information regarding using Mecofol Plus D3 Tablet in children is available, so please consult a doctor. Pregnant women and nursing mother should consult their doctor before taking the Mecofol Plus D3 Tablet .

Uses of Mecofol Plus D3 Tablet

Mecofol Plus D3 Tablet is used in the treatment and management of neuropathic pain (nerve pain) and nutritional deficiencies. The detailed uses of Mecofol Plus D3 Tablet are as follows:

  • Manages Neuropathic pain: Mecofol Plus D3 Tablet is used to relieve nerve pain by regenerating damaged nerve cells and protecting nerves from damage by neutralising harmful free radicals and by forming a protective sheath (myelin).
  • Treats Diabetic Neuropathy: Mecofol Plus D3 Tablet enhances metabolism, facilitates the conversion of glucose into energy, and protects nerves from damage caused by high blood sugar.
  • Treats Peripheral Neuropathy: Mecofol Plus D3 Tablet helps repair and protect the damaged peripheral nerves, improving nerve conduction and relieving symptoms such as pain, numbness, and tingling sensations in the limbs.
  • Manages Nutritional Deficiencies: Mecofol Plus D3 Tablet helps correct and prevent deficiencies of essential nutrients in the body, such as vitamin B6, B9, B12, and D, which are vital for maintaining optimal nerve health.

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Directions for Use

  • Mecofol Plus D3 Tablet can be taken after meals to improve absorption and minimise the chance of stomach discomfort.
  • It is to be taken once daily, preferably at the same time each day, or as recommended by your doctor.
  • Swallow Mecofol Plus D3 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

  • Mecofol Plus D3 Tablet consists of five supplements: Methylcobalamin, Alpha-lipoic acid, Vitamin B6, Vitamin D3, and Folic acid. Mecofol Plus D3 Tablet is used to treat neuropathic pain and nutritional deficiencies.
  • Methylcobalamin and Vitamin B6 help rejuvenate and protect damaged nerve cells by producing a substance called myelin.
  • Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helping to provide a protective effect on the nerve tissues and brain.
  • Vitamin D3 helps in resolving neuropathic symptoms and improves balance.
  • Folic acid helps in providing essential nutrients to the nerves.
  • Together, Mecofol Plus D3 Tablet helps in providing relief from neuropathic pain.

How Mecofol Plus D3 Tablet Works

Mecofol Plus D3 Tablet consists of five supplements: Methylcobalamin, Alpha-lipoic acid, Vitamin B6, Vitamin D3, and Folic acid. Methylcobalamin and Vitamin B6 (pyridoxine) help rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that prevents oxidative stress, thereby helping to provide a protective effect on the nerve tissues and the brain. Vitamin D3 (Cholecalciferol) helps in resolving neuropathic symptoms and improves balance. Folic acid helps in providing essential nutrients. Together, Mecofol Plus D3 Tablet helps treat diabetic neuropathy and nutritional deficiencies.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mecofol Plus D3 Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Mecofol Plus D3 Tablet

Avoid exceeding the recommended dose as it might cause serious side effects. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Mecofol Plus D3 Tablet if you are allergic to any of its contents.
  • Inform your doctor before taking Mecofol Plus D3 Tablet if you have diabetes, thyroid problems, epilepsy, anaemia, infection, kidney or liver problems.
  • Consult your doctor before taking Mecofol Plus D3 Tablet if you are pregnant or breastfeeding.
  • Limited information is available regarding the usage of Mecofol Plus D3 Tablet in children, so please consult a doctor.
  • Keep your doctor informed about your health condition and the medicines you are taking to rule out any interactions.

Drug-Drug Interactions

verifiedApollotooltip
ColecalciferolCalcitriol
Severe
ColecalciferolDihydrotachysterol
Severe

Drug-Drug Interactions

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ColecalciferolCalcitriol
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
Co-administration of Cholecalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and calcitriol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolDihydrotachysterol
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
Cholecalciferol and dihydrotachysterol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and dihydrotachysterol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolErgocalciferol
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
The combined use of cholecalciferol and ergocalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and ergocalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolSucralfate
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
Taking Cholecalciferol together with Sucralfate may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Cholecalciferol and Sucralfate, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
ColecalciferolDoxercalciferol
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
Cholecalciferol and doxercalciferol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and doxercalciferol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolAluminium hydroxide
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
The combined use of aluminum hydroxide with Mecofol Plus D3 Tablet may increase the risk of toxicity.

How to manage the interaction:
Co-administration of Mecofol Plus D3 Tablet with Aluminium hydroxide can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ColecalciferolCalcifediol
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
The combined use of calcifediol with cholecalciferol can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and calcifediol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
ColecalciferolParicalcitol
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
The combined use of cholecalciferol and paricalcitol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and paricalcitol, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Folic acidColestyramine
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
Coadministration of Mecofol Plus D3 Tablet and Cholestyramine may interfere with the absorption of Mecofol Plus D3 Tablet.

How to manage the interaction:
Although taking Cholestyramine and Mecofol Plus D3 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
Folic acidSulfadiazine
Severe
How does the drug interact with Mecofol Plus D3 Tablet:
Sulfadiazine may decrease the blood levels and effects of Mecofol Plus D3 Tablet.

How to manage the interaction:
Although there is a possible interaction between Mecofol Plus D3 Tablet and Sulfadiazine, you can take these medicines together if prescribed by your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

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Alcohol

Consult your doctor

It is unknown if alcohol interacts with Mecofol Plus D3 Tablet . However, it is advisable to limit or cut down on the consumption of alcohol.

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Pregnancy

Consult your doctor

Please consult your doctor if you have any concerns; your doctor will recommend it only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Mecofol Plus D3 Tablet ; your doctor will decide whether Mecofol Plus D3 Tablet can be taken by breastfeeding mothers or not.

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Driving

Consult your doctor

It is unknown if Mecofol Plus D3 Tablet affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available regarding the usage of Mecofol Plus D3 Tablet in patients with liver problems. Please consult your doctor if you have liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Limited information is available regarding the usage of Mecofol Plus D3 Tablet in patients with kidney problems. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Limited information is available regarding the usage of Mecofol Plus D3 Tablet in children, so please consult a doctor.

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Heart

Consult your doctor if you have a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Mecofol Plus D3 Tablet should be given to elderly patients only if recommended by a doctor. Talk to your doctor if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - MEC0743

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Oct 22, 2025 | 2:07 PM IST

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