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Osteokit is used to treat osteoporosis (weak and brittle bones). It provides essential nutrients to maintain bone health, increases calcium levels, reverses bone loss and increases bone mass. In some cases, this medicine may cause side effects such as headache, indigestion, heartburn, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Osteokit

Osteokit is a combination prescription medicine used to prevent and treat osteoporosis, particularly in postmenopausal women who have a high risk of bone fractures. Depending on your doctor's assessment, it may also be prescribed for certain men or other adults with osteoporosis when treatment with this combination is considered appropriate. 

It works by slowing down the rate of bone loss while simultaneously providing the body with the essential minerals needed to rebuild and maintain strong bone structures. This medicine helps preserve bone density and lowers the likelihood of spine and hip fractures.

To achieve the best results, Osteokit must be taken consistently exactly as directed by your healthcare provider. It is typically taken on an empty stomach first thing in the morning with a full glass of plain water to ensure proper absorption and prevent throat irritation. Incorporating regular, low-impact weight-bearing exercises and eating a balanced diet rich in essential nutrients can significantly support the benefits of this treatment.

Most patients tolerate Osteokit well, but some may experience mild side effects like heartburn, indigestion, or temporary muscle aches. However, you must seek medical attention immediately if you experience severe chest pain, difficulty swallowing, severe jaw pain, or unusual thigh or hip pain, as these can point to rare but serious complications.

Before starting Osteokit, talk to your doctor if you have kidney problems, digestive issues, or difficulty sitting or standing upright for at least an hour. Do not take this if you have low blood calcium levels (hypocalcemia), severe kidney disease, or if you are unable to remain upright for 60 minutes after taking the dose, as this can lead to severe damage to your oesophagus.

This medicine can interact with other substances; for instance, taking it with tea, coffee, or calcium-rich food can stop it from absorbing properly. Additionally, alcohol and smoking should be avoided because they directly accelerate bone loss and weaken skeletal structure. If you are pregnant, breastfeeding, or an elderly individual, always consult your specialist before taking this medicine to ensure it is safe for your specific health needs. This medicine is not recommended for children, and there is limited information on its use in paediatric patients. Although dose adjustment is generally not required in people with liver impairment, tell your doctor if you have any liver problems before starting treatment.

Uses of Osteokit

Osteokit is used to prevent and treat osteoporosis. The detailed uses of Osteokit are as follows: 

  • Postmenopausal Osteoporosis: Osteokit helps reduce the risk of spinal and non-spinal fractures in women after menopause by stopping bone thinning and improving bone mineral density.
  • Senile Osteoporosis: It helps reverse age-related bone weakness in older adults by supplying active bone-building blocks and halting bone resorption.
  • Drug-Induced Osteoporosis: Osteokit helps protect and preserve bone mass in individuals undergoing long-term steroid therapy, which is known to weaken bones.

Key Benefits

Using Osteokit as prescribed may provide the following benefits: 

  • Strengthens bones and reduces fracture risk: Osteokit helps strengthen bones and reduce the risk of fractures. This supports safer movement and helps maintain an active, independent lifestyle.
  • Supports healthy bone rebuilding: This combination helps slow bone loss while supporting healthy bone formation. Together, these actions improve bone strength and support long-term bone health.
Side effects of Osteokit
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Osteokit can be taken with or without food as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Osteokit as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Osteokit Works

Osteokit combines four distinct active components that work together to restore and protect bone health: Ibandronic Acid belongs to a group of medicines called bisphosphonates. It binds directly to bone minerals and slows down osteoclasts, the specialised cells that break down bone tissue (bone breakdown or bone loss), thereby preserving overall bone density. Calcium is the primary mineral required to build and maintain the physical structure of your bones. Calcitriol is the active form of Vitamin D. It helps your digestive tract absorb calcium efficiently, supports calcium reabsorption by the kidneys, and helps regulate parathyroid hormone (PTH) (a hormone that helps control the amount of calcium in your blood), ensuring adequate calcium is available to maintain strong bones.   Zinc stimulates osteoblasts (bone-forming cells) and helps build the protein framework inside bones that gives them flexibility and strength.
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Osteokit.

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Pregnancy

Caution

Ibandronic acid in Osteokit is not recommended during pregnancy. Please consult your doctor for more information.

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Breast Feeding

Caution

Consult your doctor before taking Osteokit if you are breastfeeding. Osteokit can pass into the breast milk. Ibandronic acid in Osteokit is not recommended during breastfeeding.

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Driving

Safe if prescribed

Osteokit has negligible effects on driving ability.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Osteokit. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek doctor advice before starting Osteokit if you have kidney stones or undergoing dialysis. Calcitriol in Osteokit increases inorganic phosphate levels in serum; hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Unsafe

Osteokit is not recommended for children and adolescents below 18 years.

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Heart

Caution

Let your doctor know if you have heart disease before taking Osteokit. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Osteokit should be given to elderly patients only if prescribed by a doctor. If you have any concerns about using Osteokit in geriatrics, please consult your doctor.

What if I have taken an overdose of Osteokit

If you take more than the prescribed dose of Osteokit, do not induce vomiting. Seek immediate medical attention, contact your local poison control centre, or call your local emergency medical services immediately. Do not eat or drink anything unless instructed by a healthcare professional.

Diet & Lifestyle Advise

  • Prioritise Dietary Calcium: Include low-fat dairy, fortified plant milks, leafy green vegetables, and almonds in your meals to support your bone rebuilding process naturally.
  • Stay Safe in the Sun: Spend a short amount of time in safe morning sunlight to assist your body in producing natural vitamin D, which works alongside the calcitriol in Osteokit.
  • Engage in Safe Exercise: Incorporate regular, low-impact weight-bearing activities like walking, climbing stairs, or light resistance exercises to naturally stimulate bone cells to strengthen.
  • Avoid Bone Depleters: Avoid smoking and limit your intake of alcohol and highly caffeinated drinks, as these substances interfere with calcium absorption and accelerate bone loss.
health query

Have a query?

How Soon It Starts Working

The time required for Osteokit to start to work: The time required for Osteokit to show its action is unknown. The time for which the effects of Osteokit last: The duration of action for Osteokit is clinically unknown.

Storage

• Store Osteokit at room temperature, ideally between 15°C to 30°C (59°F to 86°F).

What if you forget to take Osteokit

If you miss your scheduled dose, do not take it later in the day. Skip the missed dose and take it the following morning first thing on an empty stomach, then return to your regular routine. Do not take two doses on the same day to make up for a forgotten one. If you are unsure of what to do, talk to your doctor or pharmacist.

Drug Warnings

  • Use Plain Water Only: Never take Osteokit with mineral water, juice, milk, coffee, or tea, as the minerals and compounds in these drinks will bind to the medicine and prevent your body from absorbing it.
  • Wait Before You Eat: Ensure you wait at least 60 full minutes after taking your tablet before eating breakfast or drinking anything other than plain water.
  • Maintain Upright Posture: Do not recline, lie down, or slouch heavily for 60 minutes after taking the tablet to protect your oesophagus from severe irritation or damage.
  • Inform Your Dentist: Always tell your dentist that you are taking Osteokit before having any major dental procedures or extractions, as this class of medicine can occasionally affect how your jawbone heals.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact. 

  • Antacids, Iron, and Mineral Supplements: These products contain magnesium, aluminium, or iron, which can bind to Osteokit in the gut and stop its absorption. Take these at least 60 minutes after taking Osteokit.
  • Nonsteroidal Anti-inflammatory Drugs (NSAIDs like ibuprofen or naproxen): Taking these alongside Osteokit can significantly increase your risk of stomach irritation and ulcers.
  • Corticosteroids: These can lower calcium levels in your blood, meaning your doctor will need to monitor your calcium and kidney levels closely.

Drug-Drug Interactions

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How does the drug interact with Osteokit:
Co-administration of metolazone with calcitriol +Calcium carbonate can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, calcitriol+Calcium carbonate can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Osteokit:
Co-administration of Doxercalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Doxercalciferol with Calcitriol can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Osteokit:
Co-administration of Amobarbital and Calcitriol may decrease the effects of Calcitriol.

How to manage the interaction:
Co-administration of Calcitriol with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Osteokit:
Co-administration of Rifapentine with Calcitriol may decrease the effects of Calcitriol.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Osteokit:
Co-administration of Calcium carbonate may lower the effectiveness of Patiromer calcium in binding potassium.

How to manage the interaction:
Although there is an interaction, Calcium carbonate can be taken with Patiromer calcium if prescribed by the doctor. Consult the prescriber if you experience symptoms such as metabolic alkalosis like nausea, vomiting, tremor, muscle twitching, lightheadedness, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, and confusion. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Osteokit:
Co-administration of Calcitriol with Carbamazepine may decrease the effects of Calcitriol.

How to manage the interaction:
Although there is an interaction, Calcitriol can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Osteokit:
Coadministration of dolutegravir with zinc sulfate+Calcium carbonate can reduce the efficacy of dolutegravir.

How to manage the interaction:
Although taking dolutegravir and zinc sulfate+Calcium carbonate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take dolutegravir either two hours before or six hours after taking a dose of zinc sulfate+Calcium carbonate. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Osteokit:
Taking Calcitriol with Fosphenytoin can reduce the levels and efficacy of Calcitriol.

How to manage the interaction:
Taking Calcitriol with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Osteokit:
Co-administration of Ergocalciferol and Calcitriol are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Calcitriol can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Osteokit:
Co-administration of calcitriol + calcium carbonate with digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, calcitriol + calcium carbonate can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, a slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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  • Calcium-rich foods and dairy: Milk, cheese, yoghurt, and calcium-fortified juices block the body from absorbing the active ingredients if consumed within 60 minutes of taking the tablet.
CALCITRIOL-0.25MG+CALCIUM-200MG+IBANDRONIC ACID-150MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate

Drug-Food Interactions

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CALCITRIOL-0.25MG+CALCIUM-200MG+IBANDRONIC ACID-150MG+ZINC-7.5MGFiber rich foods, Potassium rich foods
Moderate
Common Foods to Avoid:
Spinach

How to manage the interaction:
foods high in oxalic acid (spinach) may decrease calcium absorption. Consider taking calcium at least 2 hours before or after eating meals high in oxalic acid or phytic acid.

Habit Forming

No

Therapeutic Class

[BONE ENHANCERS]

FAQs

Osteokit treats low levels of calcium in the blood and osteoporosis. It consists of Calcium, Calcitriol, Zinc, and Ibandronic acid. These medicines help in providing calcium to the body and help in bone formation and maintenance. Osteokit further helps in restoring bone mass and reduces the chances of easy fractures.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Osteokit may cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Osteokit if you have any kidney problems or a history of kidney stones.
Osteokit is used to increase low levels of calcium in the body. Hence it is not advised to use Osteokit during hypercalcemia since it causes the overdose of calcium leading to kidney stones and other effects.
Calcitriol in Osteokit can increase inorganic phosphate levels in serum; hence it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low phosphate diet to control serum phosphorus levels in patients undergoing dialysis.
One of the key ingredients in Osteokit can cause severe irritation, inflammation, or ulcers in your oesophagus (food pipe) if it washes back up. Staying completely upright uses gravity to keep the tablet in your stomach where it can dissolve safely. Talk to your doctor if you cannot stand or sit upright for this long.
No. Coffee, tea, and other beverages interfere significantly with how your body absorbs this medicine, making it much less effective. You must take Osteokit only with plain water and wait at least 60 minutes before having any other drinks. Talk to your pharmacist for more advice.
Tell your dentist immediately that you are taking Osteokit. This medicine can rarely cause a condition called osteonecrosis of the jaw (delayed healing of the jawbone). Your dentist and doctor will coordinate to decide if you need to pause the medicine temporarily. Talk to your doctor before any major dental work.
No, Osteokit is generally not recommended for use during pregnancy or breastfeeding, as the active minerals and drugs can affect fetal bone development and may pass into breast milk. Talk to your doctor to explore safer alternative options.
Your doctor will monitor your blood calcium, phosphorus, and kidney function regularly to ensure your body is processing the minerals and medicine safely and to adjust your therapy as needed. Talk to your doctor to schedule these routine checks.
Yes, but you must not take them at the same time. Any other calcium supplements, multivitamins, or antacids must be taken at least 60 minutes after you have taken your Osteokit tablet to prevent absorption issues. Talk to your pharmacist to help organise your daily schedule.
While rare, signs of a serious allergic reaction include hives, swelling of the face, lips, tongue, or throat, severe dizziness, and difficulty breathing. If you experience any of these symptoms, seek emergency medical care immediately. Talk to your doctor if you have a history of allergies to bone  medicine.

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Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - OST0076
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