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Silveran Cream 15 gm is used to treat burns and prevent skin infections. It contains Silver sulfadiazine and Chlorhexidine, which inhibit the production of folic acid (a vitamin) necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Also, it works by binding to the skin strongly and kills micro-organisms on the skin and prevents infection. In some cases, you may experience irritation, itching, or burning sensation at the site of application.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Rhon Poule Life Sciences

Consume Type :

Topical

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Silveran Cream 15 gm

Silveran Cream 15 gm is a topical cream prescribed primarily to prevent and treat infections in people with second- and third-degree burn wounds. By keeping the wound clean and free of bacteria, it plays a vital role in preventing serious skin infections and supporting the body's natural recovery process. It is also used to protect skin graft areas and chronic ulcers from bacterial contamination.

For the best results, Silveran Cream 15 gm must be applied consistently as directed by your healthcare professional, usually once or twice every day. Since this is a topical cream applied directly to the skin, it does not need to be timed around your meals. To help your skin recover more effectively, it is highly recommended to follow a protein-rich diet and stay hydrated, as these lifestyle choices provide the building blocks your body needs to rebuild skin tissue.

While Silveran Cream 15 gm is highly effective, some people may experience mild side effects, such as temporary skin itching, burning, or a grayish discolouration of the skin. If you notice any signs of a severe allergic reaction, such as a severe skin rash, breathing difficulties, or swelling of your face, you must stop using the cream and seek immediate medical care. Always consult your doctor or pharmacist if you experience any unexpected or worsening skin symptoms.

Before you begin using Silveran Cream 15 gm, tell your doctor if you have certain health conditions, especially liver or kidney disease, or a genetic condition known as G6PD deficiency. Do not use this cream if you are treating a premature infant or a newborn in their first few months of life, as their bodies cannot process the ingredients safely. It should also be avoided in the late stages of pregnancy.

This cream may interact with other topical products or certain oral medicines, so always inform your healthcare provider about everything you are applying to your skin or taking by mouth. If you are pregnant, breastfeeding, or caring for an elderly patient, talk to your doctor or pharmacist to ensure Silveran Cream 15 gm is the safest option for your specific situation.

Uses of Silveran Cream 15 gm

Silveran Cream 15 gm is used to prevent and treat bacterial infections in damaged skin and wounds. It is commonly applied to burns, ulcers, and graft sites where infection control is essential for proper healing, including:

  • Burn wound infections: Silveran Cream 15 gm helps prevent and treat bacterial growth in second- and third-degree burns, keeping the wound clean and sterile.
  • Skin graft protection: It protects newly grafted skin areas from environmental bacteria, reducing the risk of graft rejection due to local infection.
  • Chronic ulcer treatment: It is used to clear bacterial infections in long-term skin sores, such as pressure wounds or diabetic leg ulcers.

Key Benefits

By combining two powerful antimicrobial agents, Silveran Cream 15 gm provides several benefits that support wound healing and infection prevention, including:

  • Broad-Spectrum Infection Protection: Helps control a wide range of bacteria that commonly infect burns and open wounds.
  • Reduces the Risk of Serious Complications: Prevents local wound infections from progressing into more severe or systemic infections.
  • Supports Wound Healing: Maintains a cleaner wound environment, allowing the body's natural healing processes to work more effectively.
  • Protects Vulnerable Skin Areas: Provides ongoing antimicrobial protection for burns, skin grafts, and chronic ulcers.
  • Helps Maintain a Moist Healing Environment: The cream base helps keep wounds appropriately moisturised, which can support tissue repair.
  • Improves Comfort During Recovery: Forms a protective barrier over damaged skin, helping reduce irritation from external contaminants and dressing changes.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Apply a small amount of Silveran Cream 15 gm on the clean and dry affected area with the help of an applicator or a clean cotton ball, or a swab as directed by the doctor.
  • Silveran Cream 15 gm is for external use only.
  • Avoid contact of Silveran Cream 15 gm with nose, mouth or eyes. If contact occurs, rinse with water.

How Silveran Cream 15 gm Works

Silveran Cream 15 gm contains two active medicines that work together to prevent and treat skin infections in wounds and burns. Silver sulfadiazine is an antibacterial medicine that works by slowly releasing silver ions into the affected area. These silver ions damage bacterial cells and interfere with their growth and multiplication, helping to control and eliminate infection. Chlorhexidine gluconate is an antiseptic agent that works by disrupting the outer membrane of bacteria. This causes the bacterial cells to leak their contents and die, helping to reduce the number of harmful microorganisms on the skin and wound surface. Together, these medicines help prevent infection, keep wounds clean, reduce bacterial growth, and support the natural healing process of the skin.
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Alcohol

Caution

The interaction of Silveran Cream 15 gm with alcohol is unknown. Please consult a doctor before consuming alcohol while using Silveran Cream 15 gm.

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Pregnancy

Unsafe

Silveran Cream 15 gm is a category B pregnancy drug and is usually not recommended for pregnant women as it may cause adverse effects in the new-born. However, please consult a doctor if you are pregnant before using Silveran Cream 15 gm.

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Breast Feeding

Caution

Silveran Cream 15 gm may be excreted in human milk and cause harm to the baby. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Silveran Cream 15 gm usually does not affect your ability to drive or operate machinery.

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Liver

Caution

If you have any concerns regarding the use of Silveran Cream 15 gm in patients with liver problems, please consult a doctor.

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Kidney

Caution

If you have any concerns regarding the use of Silveran Cream 15 gm in patients with kidney problems, please consult a doctor.

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Children

Caution

Silveran Cream 15 gm is not recommended for babies below 2 months of age as it may cause severe irritation. However, Silveran Cream 15 gm should be used with caution in children above 2 months if prescribed by a doctor.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Silveran Cream 15 gm in elderly patients. Please consult your doctor.

What if I have taken an overdose of Silveran Cream 15 gm

Because Silveran Cream 15 gm is applied to the skin, an accidental overdose from normal topical use is rare. However, if the cream is swallowed, or if it is applied excessively over massive areas of the body and you feel unwell, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Eat a protein-rich diet: Include lean meats, fish, eggs, dairy, beans, or tofu in your daily meals to provide the amino acids your body needs for skin repair.
  • Stay hydrated: Drink plenty of water throughout the day. Healing wounds require proper skin hydration to recover efficiently.
  • Increase Vitamin C and Zinc: Eat foods like bell peppers, citrus fruits, nuts, and seeds, which are clinically known to support collagen production and immune health.
  • Avoid smoking: Tobacco smoke constricts blood vessels, reducing the delivery of oxygen and vital nutrients to your healing skin, which can significantly delay recovery.
health query

Have a query?

How Soon It Starts Working

The time required for Silveran Cream 15 gm to start to work: The time required for Silveran Cream 15 gm to show its action is not clinically established. The time for which the effects of Silveran Cream 15 gm last: The duration of action for Silveran Cream 15 gm is not clinically established.

Storage

•Store Silveran Cream 15 gm at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the container tightly closed when not in use to protect the cream from contamination.

What if you forget to take Silveran Cream 15 gm

If you realise you have missed an application, apply Silveran Cream 15 gm as soon as possible. However, if it is almost time for your next scheduled application, skip the missed dose and return to your regular routine. Do not apply a double layer of cream to make up for a missed application.

Drug Warnings

  • Check the colour: Always inspect the cream before applying. If it has turned dark gray, black, or has separated, do not use it and consult your pharmacist.
  • Use sterile tools: Never dip your bare fingers directly into the jar if you are not wearing sterile gloves. Use a sterile applicator to avoid introducing bacteria into the container.
  • Protect treated areas from the sun: This medicine can make your skin more sensitive to sunlight, which may cause dark skin staining. Keep treated areas shaded or covered when outdoors.
  • Limit use on large areas: If you are applying the cream to a very large part of your body, talk to your doctor regularly to monitor your blood counts and kidney function.
  • Avoid contact with clothing: The cream can cause gray or silver staining on fabrics, so cover the application site with sterile dressings if needed to protect your clothes.

verifiedApollotooltip

Silveran Cream 15 gm may interact with certain medicines applied to wounds or absorbed into the body, potentially affecting treatment effectiveness or increasing the risk of side effects, including:

  • Topical enzymatic debriding agents (like collagenase): Silveran Cream 15 gm can deactivate these enzymes, preventing them from clearing away dead skin tissue. Do not use them together on the same wound.
  • Oral sulfonamide medicines: Combining this topical cream with oral sulfa drugs may increase the risk of systemic side effects, such as changes in your blood cell levels.

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verifiedApollotooltip

No clinically significant food interactions are known with Silveran Cream 15 gm when used as directed. 

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS- TOPICAL ANTIBIOTICS/ANTIMICROBIALS]

FAQs

Silveran Cream 15 gm is used to treat burns and prevent skin infections.
Silveran Cream 15 gm contains Silver sulfadiazine and Chlorhexidine. Silver sulfadiazine is an antibiotic that works by inhibiting the production of folic acid (a vitamin) that is necessary for bacteria to multiply and increase in numbers. Thereby, destroys bacteria. Chlorhexidine is an antiseptic that works by binding to the skin strongly and kills micro-organisms on the skin. Together, Silveran Cream 15 gm helps to clean the skin and prevent infection.
Yes, Silveran Cream 15 gm may cause itching of the skin at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.
You are not recommended to use Silveran Cream 15 gm with prilocaine (local anaesthetic) as it may increase the risk of methemoglobinemia (a blood disorder in which very less oxygen is delivered to vital organs and tissues). If you experience shortness of breath, dizziness, rapid heartbeat, anxiety, light-headedness, grey discolouration of the skin, nail bed or mouth, confusion, headache, nausea or tiredness, please consult a doctor immediately. However, consult your doctor before using Silveran Cream 15 gm with other medicines.
Silveran Cream 15 gm may cause staining of clothes as it contains Chlorhexidine responsible for staining. Therefore, avoid contact of Silveran Cream 15 gm with clothes or fabric and also avoid bleach to wash fabric that is in contact with Silveran Cream 15 gm as it may cause a permanent stain.
You are recommended to use Silveran Cream 15 gm for as long as your doctor has prescribed it. However, if the condition persists or worsens after using Silveran Cream 15 gm for 1 week, please consult a doctor.
The common side effects of Silveran Cream 15 gm are irritation, itching, or burning sensation at the site of application. If any of these side effects persist or worsen, please consult your doctor.
Silveran Cream 15 gm is designed specifically for moderate to severe burns, skin grafts, and specific chronic ulcers. For minor everyday cuts or scrapes, ask your doctor or pharmacist to recommend a standard first-aid antiseptic cream instead.
If the cream in your container has turned dark gray or black, it may have lost its effectiveness due to exposure to light or heat. Do not apply it; bring it to your pharmacist for advice or a replacement.
You should avoid using Silveran Cream 15 gm during the late stages of pregnancy (near the due date) as it may cause complications for the newborn. Always talk to your doctor to weigh the benefits and risks if you are pregnant.
Yes, you can cover the area with sterile gauze dressings as directed by your doctor. However, ensure that a continuous layer of the cream remains on the wound, and reapply it if the dressing absorbs the cream.
Silveran Cream 15 gm starts working immediately to prevent bacterial growth. The overall healing time of your skin depends on the size and severity of your wound. Talk to your doctor to monitor your progress.
Do not use Silveran Cream 15 gm on premature infants or newborns during their first two months of life, as their organs are not mature enough to process the absorbed ingredients safely. Talk to your doctor for safer alternatives.
The cream may cause a temporary grey or brownish discolouration of the skin at the application site. This staining usually fades after you stop using the medicine and the skin fully heals. Talk to your doctor if you have concerns.
You should avoid mixing or layering other topical creams, ointments, or skin cleansers with Silveran Cream 15 gm unless your doctor explicitly tells you to do so, as they may interfere with how this medicine works.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

29/3, 29/4, 29/5, 2th Floor, Part 3", Talawall Chanda Near Panchwati Colony, Lasudia Mori, Dewas Naka,
Other Info - SIL1026
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