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Jan-27
Drug-Drug Interactions
AmlodipineDantrolene
Critical
Severe
Drug-Drug Interactions
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AmlodipineDantrolene
Critical
How does the drug interact with Affobis AM 2.5 Tablet:
Using Affobis AM 2.5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Affobis AM 2.5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Using Affobis AM 2.5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Affobis AM 2.5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Coadministration of Ceritinib together with Affobis AM 2.5 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although there is an interaction between Affobis AM 2.5 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Ceritinib together with Affobis AM 2.5 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although there is an interaction between Affobis AM 2.5 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Coadministration of Affobis AM 2.5 Tablet and rifampicin together may lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Affobis AM 2.5 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Affobis AM 2.5 Tablet and rifampicin together may lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Affobis AM 2.5 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Using Affobis AM 2.5 Tablet and phenytoin together may drastically lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although Affobis AM 2.5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Affobis AM 2.5 Tablet and phenytoin together may drastically lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although Affobis AM 2.5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Co-administration of Tizanidine and Affobis AM 2.5 Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Affobis AM 2.5 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Co-administration of Tizanidine and Affobis AM 2.5 Tablet can increase the risk or severity of developing side effects like low blood pressure.
How to manage the interaction:
Although co-administration of Affobis AM 2.5 Tablet with tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not discontinue any medications without consulting the doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Using phenobarbital and Affobis AM 2.5 Tablet may drastically lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of phenobarbital with Affobis AM 2.5 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using phenobarbital and Affobis AM 2.5 Tablet may drastically lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of phenobarbital with Affobis AM 2.5 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineNitisinone
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Coadministration of Affobis AM 2.5 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.
How to manage the interaction:
Taking Nitisinone with Affobis AM 2.5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Coadministration of Affobis AM 2.5 Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.
How to manage the interaction:
Taking Nitisinone with Affobis AM 2.5 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Using Affobis AM 2.5 Tablet and primidone together may lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Affobis AM 2.5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Affobis AM 2.5 Tablet and primidone together may lower Affobis AM 2.5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although co-administration of Affobis AM 2.5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Coadministration of Affobis AM 2.5 Tablet and carbamazepine together may significantly reduce Affobis AM 2.5 Tablet blood levels, making the medicine less effective.
How to manage the interaction:
Although there is an interaction between Affobis AM 2.5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Affobis AM 2.5 Tablet and carbamazepine together may significantly reduce Affobis AM 2.5 Tablet blood levels, making the medicine less effective.
How to manage the interaction:
Although there is an interaction between Affobis AM 2.5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Affobis AM 2.5 Tablet:
Taking simvastatin with Affobis AM 2.5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Affobis AM 2.5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking simvastatin with Affobis AM 2.5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Affobis AM 2.5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
AMLODIPINE-5MG+BISOPROLOL-2.5MGFruit juices, Fruits
Mild
Drug-Food Interactions
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AMLODIPINE-5MG+BISOPROLOL-2.5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking grapefruit or grapefruit juice with Affobis AM 2.5 Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking grapefruit or grapefruit juice with Affobis AM 2.5 Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.
Product Substitutes
शराब
Unsafe
अप्रिय दुष्प्रभावों से बचने के लिए आपको शराब के साथ शराब का सेवन न करने की सलाह दी जाती है।
गर्भावस्था
Unsafe
Affobis AM 2.5 Tablet 10's को तब तक नहीं लेना चाहिए जब तक कि उसे डॉक्टर द्वारा निर्धारित न किया जाए। Affobis AM 2.5 Tablet 10's के बच्चे (भ्रूण) पर कुछ हानिकारक प्रभाव हो सकते हैं, आपके डॉक्टर इसे आपको देने से पहले इसके लाभों और किसी भी संभावित जोखिम का आकलन करेंगे। कृपया अपने डॉक्टर से परामर्श करें।
स्तनपान
Caution
Affobis AM 2.5 Tablet 10's को आमतौर पर स्तनपान कराने वाली माताओं के लिए अनुशंसित नहीं किया जाता है। सीमित मानव डेटा उपलब्ध है जो बताता है कि दवा बच्चे को कोई महत्वपूर्ण नुकसान नहीं पहुंचाती है। केवल तभी सेवन करें जब लाभ जोखिम से अधिक हो।
ड्राइविंग
Unsafe
Affobis AM 2.5 Tablet 10's लेने के बाद गाड़ी चलाने की अनुशंसा नहीं की जाती है क्योंकि इससे कभी-कभी उनींदापन या थकान हो सकती है।
जिगर
Caution
Affobis AM 2.5 Tablet 10's को सावधानी से लिया जाना चाहिए, खासकर अगर आपको लिवर की बीमारियों/स्थितियों का इतिहास है। खुराक को आपके डॉक्टर द्वारा समायोजित किया जाना पड़ सकता है।
किडनी
Caution
Affobis AM 2.5 Tablet 10's सावधानी के साथ लिया जाना चाहिए, खासकर अगर आपको किडनी की बीमारियों/स्थितियों का इतिहास है। खुराक को आपके डॉक्टर द्वारा समायोजित किया जाना पड़ सकता है।
बच्चे
Unsafe
Affobis AM 2.5 Tablet 10's बच्चों के लिए अनुशंसित नहीं है। बच्चों में Affobis AM 2.5 Tablet 10's की सुरक्षा और प्रभावकारिता अभी तक स्थापित नहीं हुई है।
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