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Aprecap 125/80 Capsule Kit is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. It contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

निर्माता/विपणक :

ग्लेनमार्क फार्मास्यूटिकल्स लिमिटेड

उपभोग प्रकार :

मौखिक

वापसी नीति :

वापसी योग्य नहीं

को या उसके बाद समाप्त हो जाएगा :

Jan-27
Side effects of Aprecap 125/80 Capsule Kit

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Drug-Drug Interactions

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Drug-Drug Interactions: Avoid taking Aprecap 125/80 Capsule Kit with antipsychotics (pimozide), antiallergic drugs (terfenadine, astemizole), and gastroprokinetic agents (cisapride). Aprecap 125/80 Capsule Kit may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), the medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressant (nefazodone), corticosteroids (dexamethasone, methylprednisolone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.

Drug-Food Interactions: Aprecap 125/80 Capsule Kit may interact with St. John’s Wort (herbal preparation used to treat depression).

Drug-Disease Interactions: If you have liver disease, inform your doctor before taking Aprecap 125/80 Capsule Kit.

AprepitantLomitapide
Critical

Drug-Drug Interactions

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How does the drug interact with Aprecap 125/80 Capsule Kit:
Using pimozide together with Aprecap 125/80 Capsule Kit may significantly increase the blood levels of pimozide. High blood levels of pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Aprecap 125/80 Capsule Kit and Pimozide together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
AprepitantLomitapide
Critical
How does the drug interact with Aprecap 125/80 Capsule Kit:
Lomitapide blood levels can be significantly increased by combining it with Aprecap 125/80 Capsule Kit.

How to manage the interaction:
Although using Lomitapide and Aprecap 125/80 Capsule Kit together may cause an interaction, they can be taken if advised by a doctor. Consult a doctor if you have any of the following symptoms: diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, liver problems causing fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AprepitantFlibanserin
Critical
How does the drug interact with Aprecap 125/80 Capsule Kit:
Using flibanserin together with Aprecap 125/80 Capsule Kit can significantly increase the blood levels of flibanserin.

How to manage the interaction:
Taking Flibanserin and Aprecap 125/80 Capsule Kit together is not recommended as it can lead to an interaction; they can be taken if prescribed by a doctor. Consult a doctor if you develop any symptoms, such as extreme sleepiness or low blood pressure, that cause dizziness, lightheadedness, or fainting. To reduce the chance of these side effects, use Flibanserin at bedtime. Do not discontinue any medications without consulting a doctor.
AprepitantEliglustat
Critical
How does the drug interact with Aprecap 125/80 Capsule Kit:
Aprecap 125/80 Capsule Kit combined with Eliglustat can considerably raise blood levels of Eliglustat. This raises the possibility of cardiac adverse effects such as abnormal heart rhythm, heart block, and cardiac arrest.

How to manage the interaction:
Taking Aprecap 125/80 Capsule Kit and Eliglustat together is not recommended as it can lead to an interaction; they can be consumed if prescribed by a doctor. Consult a doctor if you have symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, weak heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Aprecap 125/80 Capsule Kit:
Co-administration with Aprecap 125/80 Capsule Kit and Cisapride may cause irregular heart rhythm.

How to manage the interaction:
Although taking Aprecap 125/80 Capsule Kit and Cisapride together is not recommended as it can lead to an interaction, it is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantAstemizole
Critical
How does the drug interact with Aprecap 125/80 Capsule Kit:
Co-administration with Aprecap 125/80 Capsule Kit and Astemizole may increase the blood levels of Astemizole.

How to manage the interaction:
Although taking Aprecap 125/80 Capsule Kit and Astemizole together is not recommended as it can lead to an interaction, it is safe if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor. Astemizole should not be combined with any other medications without a doctor's advice.
AprepitantTerfenadine
Critical
How does the drug interact with Aprecap 125/80 Capsule Kit:
Co-administration with Aprecap 125/80 Capsule Kit and Terfenadine may increase the blood levels of Terfenadine and leads to irregular heartbeat.

How to manage the interaction:
Taking Aprecap 125/80 Capsule Kit and Terfenadine together is not recommended as it can lead to an interaction. It is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Aprecap 125/80 Capsule Kit:
Co-administartion of Aprecap 125/80 Capsule Kit and Ivabradine may significantly increase the blood levels of Ivabradine which can result in excessive slowing of heart rate or other side effects.

How to manage the interaction:
Although there is an interaction between Aprecap 125/80 Capsule Kit and Ivabradine, it can be taken if prescribed by a doctor. If you have dizziness, tiredness, low blood pressure, heart palpitations, chest pain, or worsening shortness of breath, you should see a doctor. Without consulting a doctor, never stop taking medicines.
How does the drug interact with Aprecap 125/80 Capsule Kit:
Eplerenone levels in the blood may be significantly elevated by Aprecap 125/80 Capsule Kit.This could make adverse effects more severe.

How to manage the interaction:
Although coadministration of Aprecap 125/80 Capsule Kit and Eplerenone can lead to an interaction, they can be taken if prescribed by a doctor Consult a doctor if you have any kidney-related symptoms (swollen ankles, tiredness, shortness of breath, difficulty in sleeping, itchy skin), nausea, vomiting, weakness, confusion, tingling in the hands and feet, heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Without consulting a doctor, never stop taking medicines.
How does the drug interact with Aprecap 125/80 Capsule Kit:
Coadministration of Everolimus with Aprecap 125/80 Capsule Kit blood levels may considerably increase the blood level of the Aprecap 125/80 Capsule Kit, which increases the severity of serious side effects (pneumonitis - inflammation of the lungs, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although co-administration of Aprecap 125/80 Capsule Kit and Everolimus can lead to an interaction, it can be taken if prescribed by a doctor. Consult a doctor if you suffer any symptoms, including bleeding, anemia, oral ulcers, infection, lung problems (shortness of breath, persistent cough, tiredness). Without consulting a doctor, never stop taking medicines.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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निर्माता/विपणक का पता

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - APR0024
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