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Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Combining Arpimune-O 100 mg Softgel Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Combining Arpimune-O 100 mg Softgel Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
Critical
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Coadministration of pitavastatin with Arpimune-O 100 mg Softgel Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Arpimune-O 100 mg Softgel Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Coadministration of pitavastatin with Arpimune-O 100 mg Softgel Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).
How to manage the interaction:
Taking Pitavastatin with Arpimune-O 100 mg Softgel Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
Critical
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
Taking cyclosporine with cidofovir can increase the risk of kidney problems.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinEdoxaban
Severe
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Taking edoxaban and Arpimune-O 100 mg Softgel Capsule can significantly increase the blood levels of edoxaban.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, bruising, blood in stools or urine, dizziness, severe headache, weakness, or vomiting contact a doctor. Do not stop using any medications without a doctor's advice.
Taking edoxaban and Arpimune-O 100 mg Softgel Capsule can significantly increase the blood levels of edoxaban.
How to manage the interaction:
Taking Arpimune-O 100 mg Softgel Capsule with edoxaban together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience bleeding, bruising, blood in stools or urine, dizziness, severe headache, weakness, or vomiting contact a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinIohexol
Severe
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Coadministration of iohexol with Arpimune-O 100 mg Softgel Capsule may increases the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between iohexol and Arpimune-O 100 mg Softgel Capsule, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not stop using any medications without talking to a doctor.
Coadministration of iohexol with Arpimune-O 100 mg Softgel Capsule may increases the risk of kidney problems.
How to manage the interaction:
Although there is a possible interaction between iohexol and Arpimune-O 100 mg Softgel Capsule, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Taking carbamazepine and Arpimune-O 100 mg Softgel Capsule may decrease the effects of Arpimune-O 100 mg Softgel Capsule.
How to manage the interaction:
Although taking carbamazepine and Arpimune-O 100 mg Softgel Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking carbamazepine and Arpimune-O 100 mg Softgel Capsule may decrease the effects of Arpimune-O 100 mg Softgel Capsule.
How to manage the interaction:
Although taking carbamazepine and Arpimune-O 100 mg Softgel Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
Co-administration of dabigatron etexilate with Arpimune-O 100 mg Softgel Capsule may increase the blood levels of dabigatron etexilate.
How to manage the interaction:
Although there is a possible interaction between dabigatron etexilate and Arpimune-O 100 mg Softgel Capsule, you can take these medicines together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms such as bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Co-administration of dabigatron etexilate with Arpimune-O 100 mg Softgel Capsule may increase the blood levels of dabigatron etexilate.
How to manage the interaction:
Although there is a possible interaction between dabigatron etexilate and Arpimune-O 100 mg Softgel Capsule, you can take these medicines together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms such as bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Arpimune-O 100 mg Softgel Capsule:
The combined use of aliskiren and Arpimune-O 100 mg Softgel Capsule can significantly increase the blood levels and effects of aliskiren, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.
How to manage the interaction:
Taking aliskiren and Arpimune-O 100 mg Softgel Capsule will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.
The combined use of aliskiren and Arpimune-O 100 mg Softgel Capsule can significantly increase the blood levels and effects of aliskiren, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.
How to manage the interaction:
Taking aliskiren and Arpimune-O 100 mg Softgel Capsule will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.
Drug-Food Interactions
CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Arpimune-O 100 mg Softgel Capsule can increase the effects of Arpimune-O 100 mg Softgel Capsule. Avoid consuming grapefruit and grapefruit juice while taking Arpimune-O 100 mg Softgel Capsule.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Arpimune-O 100 mg Softgel Capsule can increase the effects of Arpimune-O 100 mg Softgel Capsule. Avoid consuming grapefruit and grapefruit juice while taking Arpimune-O 100 mg Softgel Capsule.
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