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Enam 2.5 Tablet is used to treat hypertension and heart failure. It relaxes and widens blood vessels, helping the heart pump blood more easily. This helps reduce symptoms like swelling, shortness of breath, and tiredness, and lowers the risk of hospitalisation and complications such as heart attack, stroke, and kidney damage.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Enam 2.5 Tablet
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.

Drug-Drug Interactions

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EnalaprilEprosartan
Severe

Drug-Drug Interactions

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How does the drug interact with Enam 2.5 Tablet:
Using aliskiren together with Enam 2.5 Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Enam 2.5 Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
EnalaprilEprosartan
Severe
How does the drug interact with Enam 2.5 Tablet:
Coadministration of Enam 2.5 Tablet with Eprosartan may raise the risk of hyperkalemia, hypotension, syncope, and renal failure due to additive or synergistic effects. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enam 2.5 Tablet together with Eprosartan may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Using Enam 2.5 Tablet together with Irbesartan may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Irbesartan with Enam 2.5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without talking to a doctor.
EnalaprilPotassium citrate
Severe
How does the drug interact with Enam 2.5 Tablet:
Taking Enam 2.5 Tablet with Potassium citrate increases the potassium levels in the blood, which may lead to hyperkalemia. In severe cases, hyperkalemia may lead to muscular paralysis, kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enam 2.5 Tablet together with Potassium citrate may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Due to the additive effect, the coadministration of Enam 2.5 Tablet and Amiloride (potassium-sparing diuretic) may increase blood potassium levels. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enam 2.5 Tablet together with Allopurinol may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any signs and symptoms of hyperkalemia like, weakness, confusion, numbness or tingling, and uneven heartbeats, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Due to additive or synergistic effects, coadministration of Enam 2.5 Tablet with candesartan may raise the risk of hyperkalemia, hypotension, syncope, and renal failure. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enam 2.5 Tablet together with Candesartan may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Due to additive or synergistic effects, coadministration of Enam 2.5 Tablet with Irbesartan may raise the risk of hyperkalemia, hypotension, syncope, and renal failure. In severe cases, hyperkalemia can lead to muscle paralysis,kidney damage, and cardiac problems. The risk is increased if you are elderly, dehydrated, or have a history of kidney or heart disease.

How to manage the interaction:
Although taking Enam 2.5 Tablet together with Irbesartan may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Taking Enam 2.5 Tablet and Ferric Carboxymaltoside increases the side effects of Enam 2.5 Tablet.

How to manage the interaction:
Although taking Enam 2.5 Tablet with Ferric Carboxymaltose may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience dizziness, lightheadedness, headache, blurred vision, or chest pain, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Enam 2.5 Tablet has the potential to cause liver damage; this effect can be increased by the coadministration of medications that affect the liver, such as Leflunomide. This effect can be seen even long after discontinuing leflunomide as it stays in your blood longer.

How to manage the interaction:
Although taking Enam 2.5 Tablet together with Leflunomide may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of liver damage like fever, chills, unusual bleeding, dark-coloured urine, light colour stools, yellowish discolouration of skin and eyes, and abdominal pain. It is advised not to consume alcohol while using these medications as it may increase the damage o the liver. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Enam 2.5 Tablet:
Coadministration of Ketoconazole and Enam 2.5 Tablet may increase the risk of liver problems.

How to manage the interaction:
Although taking Enam 2.5 Tablet with Ketoconazole may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience fever, dark-coloured urine, light-coloured stools, yellowish discolouration of skin and eyes, and abdominal pain. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ENALAPRIL-2.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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ENALAPRIL-2.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming a high-potassium diet while taking Enam 2.5 Tablet can cause hyperkalemia (elevated blood potassium levels). Hyperkalemia may lead to dizziness, lightheadedness, fainting, or a rapid heartbeat. Avoid the consumption of potassium-rich foods.

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