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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Neosporin Ointment 5 gm is an antibacterial medicine used to prevent bacterial skin infections that occur due to minor cuts, scrapes, or burns on the skin. This medicine is a combination of bacitracin, neomycin and polymyxin B which works by inhibiting the bacterial cell synthesis.

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Drug-Drug Interactions

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Severe
BacitracinAmikacin
Severe

Drug-Drug Interactions

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Severe
How does the drug interact with Neosporin Ointment 5 gm:
Hydroxycarbamide when used in conjunction with Neosporin Ointment 5 gm may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between hydroxycarbamide with Neosporin Ointment 5 gm, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
BacitracinAmikacin
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Coadministration of Amikacin with Neosporin Ointment 5 gm can increase the risk of developing side effects like hearing loss, difficulty breathing, or kidney problems.

How to manage the interaction:
Although taking amikacin and Neosporin Ointment 5 gm together can result in an interaction, it can be taken if a doctor has prescribed it. Consult a doctor if you experience ringing in the ears, difficulty breathing, vomiting, increased or decreased urination, swelling, muscle cramps, dizziness, or palpitations. Do not stop using any medications without talking to a doctor.
BacitracinClindamycin
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Co-administration of Clindamycin with Neosporin Ointment 5 gm may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, clindamycin can be taken with Neosporin Ointment 5 gm if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Let your doctor know if you develop seizures; hearing problems; or numbness, burning or tingling in your hands and feet. If you develop diarrhoea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may harm the kidney.
BacitracinCarboplatin
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Taking carboplatin and Neosporin Ointment 5 gm can increase the risk of nephrotoxicity(kidney damage).

How to manage the interaction:
Co-administration of carboplatin and Neosporin Ointment 5 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult the doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Coadministration of Neosporin Ointment 5 gm with Tenofovir disoproxil can increase the risk of developing kidney damage and reduced function.

How to manage the interaction:
Although there may be a possibility of interaction between Tenofovir disoproxil and Neosporin Ointment 5 gm, it can be taken when prescribed by a doctor. If you experience any symptoms, contact the doctor immediately. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Taking Human immunoglobulin with Neosporin Ointment 5 gm, may raise the risk of kidney problems.

How to manage the interaction:
Taking Human immunoglobulin with Neosporin Ointment 5 gm together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
BacitracinDeferasirox
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Deferasirox may cause kidney problems and combining it with Neosporin Ointment 5 gm may increase that risk.

How to manage the interaction:
Although taking Neosporin Ointment 5 gm and Deferasirox together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
BacitracinPolymyxin b
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Taking Polymyxin b and Neosporin Ointment 5 gm together can increase the risk of kidney and inner ear damage

How to manage the interaction:
Although taking Polymyxin b and Neosporin Ointment 5 gm together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience ringing in the ears, hearing loss, vertigo, nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
BacitracinSirolimus
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Co-administration of Neosporin Ointment 5 gm and Sirolimus can increase the risk or severity of Kidney problems.

How to manage the interaction:
Co-administration of Sirolimus with Neosporin Ointment 5 gm can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
BacitracinGentamicin
Severe
How does the drug interact with Neosporin Ointment 5 gm:
Taking gentamicin with Neosporin Ointment 5 gm may increase the risk of serious side effects such as respiratory depression, kidney problems, and hearing loss.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Neosporin Ointment 5 gm if prescribed by the doctor. Consult the prescriber if you experience hearing loss, ringing in the ears, vertigo, difficulty breathing, (or) signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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