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Olsar CH 40/12.5 Tablet 10's
Olsar CH 40/12.5 Tablet 10's
Olsar CH 40/12.5 Tablet 10's

Olsar CH 40/12.5 Tablet is used to treat hypertension (high blood pressure). It contains Olmesartan and Chlorthalidone, which relaxes blood vessels and allows the blood to flow more smoothly and the heart to pump more efficiently. Also, it removes extra water and certain electrolytes from the body. Thus, it lowers fluid overload and blood pressure and improves blood flow. In some cases, it may cause side effects such as headaches, nausea, dizziness, and cold extremes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Olsar CH 40/12.5 Tablet
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

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Drug-Drug Interactions

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Drug-Drug Interactions: Olsar CH 40/12.5 Tablet may interact with other high blood pressure-lowering pills (enalapril, captopril, lisinopril, ramipril, benazepril, diltiazem, verapamil, amiloride, metoprolol, hydrochlorothiazide, simvastatin, atorvastatin, azilsartan), medicine to treat erectile dysfunction (sildenafil), antibiotics (clarithromycin, erythromycin, rifampicin), antifungal (itraconazole, ketoconazole), anti-epilepsy medications (carbamazepine, phenytoin, phenobarbital, primidone), medicines used to treat asthma (salbutamol, formoterol),  anti-HIV drugs (ritonavir), immune-suppressing drugs (cyclosporine, tacrolimus), and pain killers (ibuprofen, naproxen, diclofenac, aspirin).

Drug-Food Interactions: Olsar CH 40/12.5 Tablet severely interacts with grapefruit, grapefruit juices, and St. John’s wort (a plant used to treat depression). Hence it should not be taken with Olsar CH 40/12.5 Tablet .

Drug-Disease Interactions: Olsar CH 40/12.5 Tablet may interact with disease conditions including low blood pressure (hypotension), heart valve problem (stenosis), cardiogenic shock (when the heart fails to pump required blood to the body), coronary heart disease, liver disease, renal impairment, or heart failure.

Olmesartan medoxomil + chlorthalidoneAliskiren
Critical
Olmesartan medoxomil + chlorthalidoneCisapride
Critical

Drug-Drug Interactions

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Olmesartan medoxomil + chlorthalidoneAliskiren
Critical
How does the drug interact with Olsar CH 40/12.5 Tablet:
WhenOlmesartan medoxomil + chlorthalidone is used together with Aliskiren , there is a risk of low blood pressure, kidney issues, and elevated potassium levels in the blood.

How to manage the interaction:
Taking Olsar CH 40/12.5 Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomil + chlorthalidoneCisapride
Critical
How does the drug interact with Olsar CH 40/12.5 Tablet:
Co-administration of Olsar CH 40/12.5 Tablet with cisapride may increase the risk of an irregular heart rhythm .

How to manage the interaction:
Taking Olsar CH 40/12.5 Tablet with Cisapride is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult a doctor. Do not discontinue the medication without consulting a doctor.
Olmesartan medoxomil + chlorthalidonePimozide
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Co-administration of Olsar CH 40/12.5 Tablet with pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Olsar CH 40/12.5 Tablet can be taken with pimozide if prescribed by the doctor. Consult a prescriber if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats, weakness, drowsiness, muscle pain, cramps, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomil + chlorthalidonePotassium chloride
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Using Olsar CH 40/12.5 Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Olsar CH 40/12.5 Tablet together with Potassium chloride can lead to an interaction but can be taken if prescribed by the doctor. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomil + chlorthalidoneLithium
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Taking Olsar CH 40/12.5 Tablet with lithium can significantly increase the blood levels of lithium leading to side effects.

How to manage the interaction:
Although taking Olsar CH 40/12.5 Tablet alongside lithium can lead to interaction, they can be taken if prescribed by a doctor. However, if you develop diarrhea, vomiting, drowsiness, tremor, thirst, increased urination, lack of coordination, confusion, tremor, blurred vision, ringing in the ear, excessive thirst, and/or increased urination, consult a doctor. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomil + chlorthalidoneAmiodarone
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Coadministration of Olsar CH 40/12.5 Tablet with amiodarone may increase the risk of abnormal heart rhythms. If you have a cardiac problem or electrolyte imbalance, you may be more vulnerable.

How to manage the interaction:
Although taking Olsar CH 40/12.5 Tablet with amiodarone may cause an interaction, it can be taken if a doctor has prescribed it. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, a rapid heartbeat, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. consult a doctor. Do not stop taking any medications without visiting a doctor.
Olmesartan medoxomil + chlorthalidoneCaptopril
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
When Olsar CH 40/12.5 Tablet is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Olsar CH 40/12.5 Tablet with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without consulting a doctor.
Olmesartan medoxomil + chlorthalidoneTizanidine
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Co-administration of Olsar CH 40/12.5 Tablet with Tizanidine may show additive effects and increase the risk of low blood pressure.

How to manage the interaction:
Although there is an interaction, Olsar CH 40/12.5 Tablet can be taken with tizanidine if prescribed by the doctor. If you experience headache, dizziness, palpitations, or sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomil + chlorthalidonePotassium citrate
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Coadministration of Olsar CH 40/12.5 Tablet with potassium citrate may increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, and abnormal heart rhythm.

How to manage the interaction:
Although taking Olsar CH 40/12.5 Tablet together with potassium citrate may result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
Olmesartan medoxomil + chlorthalidoneRamipril
Severe
How does the drug interact with Olsar CH 40/12.5 Tablet:
Coadministration of Olsar CH 40/12.5 Tablet with Ramipril can increase potassium levels in the blood, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm.

How to manage the interaction:
Although taking olmesartan medoxomil with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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CHLORTHALIDONE-12.5MG+OLMESARTAN-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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CHLORTHALIDONE-12.5MG+OLMESARTAN-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
When Olsar CH 40/12.5 Tablet is taken along with potassium-containing salt substitutes or over-the-counter potassium supplements it may lead to high potassium levels in blood. Avoid taking potassium-containing salt substitutes or over-the-counter potassium supplements with Olsar CH 40/12.5 Tablet as this can lead to high potassium levels in the blood. However, consult a doctor if you experience weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

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