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compositionComposition:ABACAVIR-300MG
prescription
Prescription Medicine
info
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Abamune Tablet is used to treat HIV infection. It contains Abacavir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cell that helps the body to fight infections. In some cases, Abamune Tablet may cause common side effects such as nausea, vomiting, headache, diarrhoea, loss of appetite, and tiredness. It is generally not recommended for use in pregnancy. Avoid breastfeeding while taking this medication. HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ABACAVIR-300MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Abamune Tablet

Abamune Tablet is an antiviral prescription medicine used to treat Human Immunodeficiency Virus type 1 (HIV-1) infection. It belongs to a class of medicines that help control the virus, keeping it from multiplying in your body. It is always used in combination with other HIV medications to provide the most effective treatment.

To get the best results, you must take Abamune Tablet every day exactly as your doctor prescribes, even when you feel well. You can take this oral medicine with or without food, making it easy to fit into your daily routine. Combining this treatment with a balanced diet, regular exercise, and avoiding smoking can further support your immune system.

While taking Abamune Tablet , some people may experience mild side effects like nausea, headache, or tiredness. However, it is critical to seek immediate medical help if you experience signs of a serious allergic reaction, such as a skin rash, fever, fatigue, or breathing difficulties. Talk to your doctor or pharmacist immediately if you notice these symptoms.

Before starting this medicine, tell your doctor if you have liver disease, kidney problems, or heart disease. Do not take this if you have tested positive for a specific gene variation called HLA-B*5701, as this greatly increases your risk of a severe, life-threatening allergic reaction. Talk to your doctor to see if you need this genetic test before starting.

Some medications and alcohol can affect how this medicine works. Alcohol can increase the levels of Abamune Tablet in your blood, which may raise your risk of side effects. If you are pregnant, breastfeeding, or planning a family, talk to your doctor to understand the risks and benefits of continuing this treatment.

Uses of Abamune Tablet

Abamune Tablet helps manage HIV-1 infection by reducing the amount of virus in the body and supporting the immune system. Your doctor may prescribe it for the following condition:

  • HIV-1 Infection: Abamune Tablet is prescribed to manage HIV-1 infection. It works alongside other antiviral medicines to lower the amount of virus in your blood and boost your immune system's helper cells (CD4 cells).

Key Benefits

Using Abamune Tablet as prescribed helps control HIV-1 infection and protect your immune system. Here are the key benefits you can expect:

  • Reduces viral load: Abamune Tablet helps prevent HIV-1 from multiplying, lowering the amount of virus in your blood.
  • Strengthens the immune system: By reducing viral activity, it helps protect and restore CD4 (helper T) cells, allowing your immune system to fight infections more effectively.
  • Supports long-term health: Consistent treatment helps reduce the risk of HIV-related complications and supports a longer, healthier life.
  • Lowers the risk of HIV transmission: Maintaining an undetectable viral load with regular treatment greatly reduces the risk of passing HIV to others through sexual contact.
Side effects of Abamune Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Abamune Tablet can be taken with or without food as advised by the doctor.
  • It is usually taken once or twice daily as advised by the doctor.
  • Swallow Abamune Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Abamune Tablet Works

Abamune Tablet contains abacavir, a nucleoside reverse transcriptase inhibitor (NRTI) that helps control HIV-1 infection by preventing the virus from multiplying. Abamune Tablet works by blocking reverse transcriptase, an enzyme that HIV uses to copy its genetic material and produce new viruses. It mimics the natural building blocks of viral DNA, interrupting the replication process and preventing the virus from multiplying. This helps reduce the amount of HIV in the blood (viral load), protects CD4 (helper T) cells from damage, and supports the normal functioning of the immune system. Abamune Tablet is used in combination with other antiretroviral medicines to provide effective long-term control of HIV-1 infection.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Abamune Tablet as it may have the risk of developing Osteonecrosis (a condition in which parts of the bone tissue die because of reduced blood supply to the bone).

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Pregnancy

Caution

Abamune Tablet is generally not recommended for use in pregnancy. If you are pregnant, inform your doctor before taking Abamune Tablet . There are limited data available on the effect of this medicine in pregnancy. Animal studies have shown carcinogenic effects.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Abamune Tablet . HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Driving

Caution

Do not drive or operate machines if you are not alert after taking this medicine.

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Liver

Caution

Abamune Tablet is primarily metabolised by the liver. No dose adjustments are necessary for patients with moderate liver impairment. If this medicine is taken in moderate liver conditions, close monitoring of liver functioning is needed. In individuals with moderate or severe hepatic impairment, abacavir should not be used unless absolutely necessary as no clinical data are available.

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Kidney

Caution

If you have kidney disease, inform your doctor before taking Abamune Tablet . Your doctor may adjust the dose if necessary based on your condition. This medicine is not recommended if you have severe kidney disease.

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Children

Caution

The safety and effectiveness of Abamune Tablet in children below three months have not been established. For children above three months, the dose, dosage form and duration will be determined by the doctor based on the child’s body weight.

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Heart

Caution

Abamune Tablet may slightly raise heart attack risk in patients with existing heart conditions, so medical supervision is essential. Discuss your cardiovascular history with your doctor before starting treatment.

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Geriatrics

Caution

Geriatric patients can take Abamune Tablet , but only with careful medical supervision. Older adults may have increased cardiovascular risks, so heart health should be evaluated before starting treatment.

What if I have taken an overdose of Abamune Tablet

In case of an accidental overdose, seek immediate medical attention or call emergency medical services. Do not wait for symptoms to appear before seeking help.

Diet & Lifestyle Advise

  • Eat a nutrient-dense diet: Focus on a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to support your overall immune function.
  • Practice safe food handling: Always wash hands, cook meat thoroughly, and avoid unpasteurised dairy products. A compromised immune system makes you more vulnerable to foodborne illnesses.
  • Stay physically active: Engage in moderate regular exercise like walking or cycling to help maintain muscle strength, support heart health, and boost your mood.
  • Limit alcohol consumption: Avoid or significantly limit alcohol while taking this medicine, as alcohol can increase drug levels in your body and put extra strain on your liver.

Health Queries

Can I get HIV from being near someone with a wound if we had no physical contact and my own wound was covered?

Vikas Singh

Vikas Singh

M Pharmacy

You cannot contract HIV this way. HIV is not airborne and cannot travel through the air or close proximity. For transmission to occur, there must be direct contact between infected blood or body fluids and an open, uncovered wound or mucous membrane. Since you had no physical contact and your own wound was safely covered, there was absolutely no risk of exposure. You are completely safe, and you do not need to worry.
health query

Have a query?

How Soon It Starts Working

The time required for Abamune Tablet to start to work: The time required for Abamune Tablet to show its action is unknown. The time for which the effects of Abamune Tablet last: The duration of action for Abamune Tablet is unknown.

What if you forget to take Abamune Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you frequently miss doses, talk to your doctor or pharmacist for tips on staying on track.

Storage

• Store Abamune Tablet tablets or oral solution at room temperature, ideally between 20°C and 25°C.Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Carry your Warning Card: Always carry the warning card provided with your medication. It lists the critical symptoms of a serious allergic reaction that require immediate emergency care.
  • Get tested first: Ensure you have completed the HLA-B*5701 genetic blood test before taking your first dose of Abamune Tablet .
  • Never restart after a reaction: If you stop taking Abamune Tablet because of a suspected allergic reaction, never restart it. Doing so can cause a life-threatening drop in blood pressure or organ failure.
  • Monitor liver health: Attend all scheduled blood tests so your doctor can monitor your liver function and viral load regularly.

Drug-Drug Interactions

verifiedApollotooltip
  • Methadone: Abamune Tablet may increase the clearance of methadone, which could require your doctor to adjust your methadone dose.
  • Riociguat: Taking these medications together may increase the levels of riociguat in your body, increasing the risk of side effects such as low blood pressure (hypotension), dizziness, or fainting. 
AbacavirLeflunomide
Severe

Drug-Drug Interactions

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AbacavirLeflunomide
Severe
How does the drug interact with Abamune Tablet:
Leflunomide can cause liver problems, and combining it with Abamune Tablet, may increase the risk.

How to manage the interaction:
Co-administration of Abamune Tablet with Leflunomide can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, joint pain, rash, or stomach problems, contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol while taking Abamune Tablet can significantly increase the concentration of the drug in your blood, raising the risk of liver strain and other side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

Abamune Tablet is used to treat HIV infection.
Abamune Tablet works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cell that helps the body to fight infection.
Abamune Tablet does not completely cure HIV infection. It reduces the viral load in the body and keeps it at a low level. Taking Abamune Tablet decreases the chance of developing AIDS and HIV-related illnesses such as cancer or serious infections.
Abamune Tablet may increase the risk of a heart attack. Therefore, inform your doctor if you have heart problems, high blood pressure, diabetes, or a habit of smoking.
Yes, Abamune Tablet is safe if taken in prescribed dose and duration prescribed by the doctor.
Abamune Tablet is anti-HIV medicine that belongs to the class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs).
Yes, Abamune Tablet is effective and may help delay the development of serious health problems that are usually related to HIV infection. However, it will not keep you from spreading HIV to other people.
Abacavir hypersensitivity is an immune-mediated reaction that typically occurs within the first 6 weeks of therapy. Consult the doctor if you experience symptoms of Abacavir hypersensitivity reaction like fever, nausea, rash, vomiting, lethargy, headache, muscle pain, joint pain or gastrointestinal symptoms.
If you miss a dose, take it as soon as you remember it. But, if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses simultaneously to make up for a missed dose.
Abamune Tablet may cause common side effects such as nausea, vomiting, headache, diarrhoea, loss of appetite, and tiredness. Most of these side effects do not require medical attention and will resolve gradually. However, consult your doctor if the side effects persist or worsen.
Yes, you can take Abamune Tablet with or without food. Taking it at the same time every day helps maintain a steady level of the medicine in your body. Talk to your doctor or pharmacist if you struggle to keep a routine.
The HLA-B*5701 test is a genetic blood test. It is used to check if you have a gene variation that makes you highly likely to have a severe, potentially life-threatening allergic reaction to Abamune Tablet . Do not take this medicine without getting this test first. Talk to your doctor to arrange this test.
If you develop symptoms such as a fever, skin rash, nausea, extreme tiredness, sore throat, or trouble breathing, stop taking the medicine immediately and seek emergency medical care. Do not take another dose. Talk to your doctor as soon as possible.
No, you must never restart Abamune Tablet if you stopped it because of a suspected allergic reaction. Restarting can lead to severe, life-threatening symptoms within hours. Talk to your doctor for alternative treatment options.
It is best to avoid or limit alcohol while taking Abamune Tablet . Alcohol can increase the amount of this medicine in your blood, which can put extra strain on your liver and increase side effects. Talk to your doctor or pharmacist about safe limits.
If you are pregnant or planning to become pregnant, you should discuss this with your healthcare provider. Your doctor will weigh the benefits of controlling your HIV against any potential risks to the baby. Talk to your doctor to find the safest treatment plan.
Yes. Abamune Tablet can be used in children 3 months of age and older when prescribed by a doctor. The dose is carefully calculated based on the child's body weight and is usually given as part of combination HIV treatment.
Yes. Abamune Tablet is commonly combined with other HIV medicines in a single tablet to make treatment simpler and reduce the number of tablets you need to take. Take your medicine exactly as prescribed and do not switch between products without your doctor's advice.

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Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ABA0001
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