Afderm Plus Cream 15 gm
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About Afderm Plus Cream
Afderm Plus Cream is a topical skin medication prescribed to treat various skin infections that are complicated by inflammation, redness, and itching. It is designed to target infections where bacteria, fungi, and skin irritation occur at the same time. This medication helps clear the underlying infection while soothing the discomfort associated with it.
For the best results, apply Afderm Plus Cream consistently at the same times every day as directed by your healthcare provider. This medication is for external use on the skin only and should never be swallowed or applied near the eyes. Keeping the affected area clean and dry will also support the medication's effectiveness.
While using Afderm Plus Cream, you may experience some mild local skin reactions like burning or stinging. If you develop severe skin irritation, peeling, or signs of an allergic reaction, stop using the product and consult your doctor immediately.
Talk to your doctor before using Afderm Plus Cream if you have thin skin, poor blood circulation, or a weakened immune system. Do not use this medicine if you have viral skin infections like chickenpox or herpes, skin tuberculosis, or a known allergy to any ingredients in the cream. Do not use this medicine to treat rosacea, acne vulgaris, or perioral dermatitis unless specifically instructed by your doctor, as the potent steroid component can worsen these conditions.
Avoid applying other skin creams or ointments to the same area at the same time, as they may interfere with the absorption of Afderm Plus Cream. If you are pregnant, breastfeeding, or treating an elderly patient, talk to your doctor or pharmacist to make sure this product is safe to use. Afderm Plus Cream is generally not recommended for young children unless prescribed by a doctor, as they absorb topical steroids more readily than adults and are at greater risk of serious side effects.
Uses of Afderm Plus Cream
Afderm Plus Cream is used in the treatment of bacterial skin infections and fungal skin infections. The detailed uses of Afderm Plus Cream are as follows:
- Mixed skin infections: Afderm Plus Cream targets skin conditions where both bacteria and fungi are present alongside inflammation.
- Infected eczema: It helps reduce severe swelling, redness, and itching while treating bacterial or fungal infections that can complicate eczematous skin.
- Infected dermatitis: Afderm Plus Cream calms itchy, irritated skin while clearing the microbes causing the infection.
Key Benefits
Afderm Plus Cream helps treat inflammatory skin conditions complicated by bacterial and fungal infections, providing relief from discomfort and supporting skin healing.
The following are the key benefits of Afderm Plus Cream:
- Helps relieve itching, redness, swelling, and skin irritation.
- Reduces bacterial and fungal infections affecting the skin.
- Improves skin comfort by calming inflammation and discomfort.
- Supports faster healing of damaged and infected skin.
- Helps prevent further skin damage caused by scratching.
- Provides comprehensive treatment by addressing inflammation, bacterial infection, and fungal infection together.
Directions for Use
- Wash your hands thoroughly with soap and water before and after applying the cream.
- Clean and completely dry the affected skin area before application.
- Apply a thin layer of Afderm Plus Cream to the affected area and gently rub it in.
- Do not cover the treated area with bandages or airtight dressings unless specifically told to do so by your doctor, as this can increase absorption and the risk of side effects.
- Always follow your doctor's exact instructions regarding how often and how long to use Afderm Plus Cream.
How Afderm Plus Cream Works
Alcohol
Caution
Alcohol may interfere with your ability to fight infections. So, it is advised to limit consumption of alcohol.
Pregnancy
Consult your doctor
Afderm Plus Cream is a category C medicine and may harm the fetus or unborn baby. So, it should be used with caution in pregnant women.
Breast Feeding
Caution
Afderm Plus Cream may pass into breast milk, so it should be used with caution in breastfeeding mothers.
Driving
Safe if prescribed
Afderm Plus Cream may not affect your ability to drive.
Liver
Caution
Afderm Plus Cream should be used with caution in patients with liver diseases. Your doctor prescribes this after weighing the benefits with any potential risks.
Kidney
Safe if prescribed
Afderm Plus Cream is probably safe when used in patients with kidney diseases.
Children
Consult your doctor
The safety of Afderm Plus Cream in children is unknown. Please consult a doctor before using Afderm Plus Cream on your child.
Heart
Consult your doctor
Please inform your doctor if you have any pre-existing heart problems.
Geriatrics
Consult your doctor
Limited information available for use of Afderm Plus Cream in elderly patients. Please consult your doctor.
What if I have taken an overdose of Afderm Plus Cream
Diet & Lifestyle Advise
- Keep skin clean and dry: Gently clean the affected area and keep it completely dry, as excess moisture can encourage the growth of bacteria and fungi.
- Wear breathable clothing: Choose loose-fitting cotton clothing to reduce friction and allow air to circulate, helping prevent sweat from building up around the treated skin.
- Avoid scratching: Do not scratch the affected area, as this can worsen irritation and increase the risk of spreading or introducing infection.
- Use gentle cleansers: Wash with mild, fragrance-free soaps or cleansers to help protect your skin and minimise further irritation while it heals.

Have a query?
How Soon It Starts Working
- The time required for Afderm Plus Cream to start to work: The time required for Afderm Plus Cream to show its action is unknown.
- The time for which the effects of Afderm Plus Cream last: The duration of action for Afderm Plus Cream is unknown.
What if you forget to take Afderm Plus Cream
Storage
Drug Warnings
- Check the tube before use: Inspect the cream tube before each use. Do not use it if the seal is broken, the tube is leaking, or the cream has changed colour.
- Avoid applying to sensitive areas: Do not apply this cream to your face, groin, or underarms unless your doctor tells you to. These areas absorb the medicine more easily and are more likely to develop side effects.
- Keep away from your eyes and mouth: Avoid getting the cream in your eyes, nose, or mouth. If accidental contact occurs, rinse the area immediately with plenty of cool water.
- Use only for the prescribed duration: Do not use this cream for longer than your doctor recommends. Prolonged use can cause skin thinning, increased absorption of the medicine, and hormone-related side effects.
- Watch for allergic skin reactions: Stop using the cream and contact your doctor if you develop a new rash, worsening redness, severe itching, or swelling after starting treatment. These may be signs of an allergic reaction.
- Do not use for certain skin conditions: Do not use this cream unless your doctor advises you to if you have viral skin infections such as chickenpox, shingles, cold sores, or herpes, or if you have skin tuberculosis, rosacea, acne, perioral dermatitis, or are allergic to any of its ingredients.
- Do not share your medicine: Use this cream only for yourself. Do not share it with others, even if they have similar skin problems.
Drug-Drug Interactions
Drug-Drug Interaction Summary:
- Topical or Oral Corticosteroids (e.g., hydrocortisone, betamethasone): Taking these medicines alongside Afderm Plus Cream may increase the risk of steroid absorption and side effects.
- Other Topical Skin Products (e.g., tretinoin, adapalene, salicylic acid): Applying these products on the same area as Afderm Plus Cream may increase the risk of skin irritation, redness, or peeling.
Drug-Drug Interactions
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Drug-Food Interactions
Drug-Food Interaction Summary:
- No clinically significant food or drink interactions are known with topical Afderm Plus Cream when used as directed.
Drug-Food Interactions
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Author Details
Reference
- Drugs.com Clinical Review Team. Clobetasol Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
- Drugs.com Clinical Review Team. Miconazole Topical Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
- U.S. Food and Drug Administration (FDA). 021535Orig1S003, 021644Orig1S003Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
- Clobetasol Clobetasol. 1993. [Accessed on 04 Apr. 2019]Check here
- Miconazole Miconazole. 1974. [Accessed on 29 Mar. 2019]Check here
- PubChem PubChem. [Accessed on 31 Mar. 2019]Check here







