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compositionComposition:KETOCONAZOLE-2%W/V+ZINC PYRITHIONE-1%W/V
prescription
Prescription Medicine
info
AF K Lotion 60 ml
AF K Lotion 60 ml
AF K Lotion 60 ml

AF K Lotion is an antifungal medication used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. It works by damaging the fungal cell membranes and killing fungi. Some people may experience side effects such as itching, redness, irritation, or a burning sensation at the site of application.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

KETOCONAZOLE-2%W/V+ZINC PYRITHIONE-1%W/V

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

Topical

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About AF K Lotion

AF K Lotion is primarily used to prevent fungal infections of the skin, like seborrheic dermatitis. Seborrheic dermatitis is a type of dandruff that causes an itchy rash with dry, flaky scales on the skin that contains oil glands, such as the scalp, face, back, and upper chest.

AF K Lotion contains ketoconazole and zinc pyrithione. It works by causing holes in the fungal cell membrane, which is essential for their survival, as it prevents the entry of unwanted substances into the cells and stops the leakage of cell contents.

Some people may experience itching, redness, irritation or a burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to AF K Lotion or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using AF K Lotion. If you are using any steroidal cream, lotion, or ointment, inform your doctor before using AF K Lotion. Do not swallow AF K Lotion. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately.

Uses of AF K Lotion

AF K Lotion is used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. The detailed uses of AF K Lotion are as follows:

  • Dandruff treatment: AF K Lotion helps reduce flakes, itching, and scalp irritation.
  • Seborrheic dermatitis management: AF K Lotion supports control of redness and scaling on the scalp.
  • Fungal infection relief: AF K Lotion helps in managing conditions caused by fungal overgrowth.
  • Localised tinea versicolor of the scalp: AF K Lotion assists in treating fungal infections that cause discoloured patches on the scalp.

Key Benefits

  • AF K Lotion is used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis.
  • It contains ketoconazole and zinc pyrithione. Ketoconazole is an antifungal agent which works by disrupting fungal cell membranes to stop their growth and spread.
  • Zinc pyrithione has broad-spectrum antimicrobial properties that help in regulating sebum production, reducing excess oil that contributes to dandruff.
  • Together, AF K Lotion helps eliminate dandruff, soothe scalp irritation, and restore scalp health.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Wet the area thoroughly before application. Massage into a lather, leave it on for a few minutes and rinse thoroughly with water.
  • Avoid contact of AF K Lotion with nose, mouth or eyes. If it accidentally comes into contact with these areas, rinse with water thoroughly.

How AF K Lotion Works

AF K Lotion contains Ketoconazole and zinc pyrithione, which work together to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis. Ketoconazole is an antifungal agent that disrupts the fungal cell membrane, preventing the growth of dandruff-causing fungi, while zinc pyrithione is a broad-spectrum antimicrobial that inhibits fungal and bacterial growth, reducing scalp irritation and flaking. Their combined action helps control scalp infections, reduce inflammation, and restore scalp health.
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Alcohol

Consult your doctor

The interaction of AF K Lotion with alcohol is unknown. Please consult a doctor before consuming alcohol while using AF K Lotion.

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Pregnancy

Consult your doctor

Please inform your doctor before using AF K Lotion if you are pregnant or plan to become pregnant. Your doctor will prescribe it only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether AF K Lotion is excreted in human milk. Please consult a doctor before using AF K Lotion while breastfeeding.

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Driving

Safe if prescribed

AF K Lotion usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of AF K Lotion in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of AF K Lotion in patients with kidney problems, please consult a doctor.

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Children

Unsafe

AF K Lotion is not recommended for children below 12 years, as the safety and effectiveness were not established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using AF K Lotion. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of AF K Lotion in elderly patients. Please consult your doctor.

What if I have taken an overdose of AF K Lotion

Do not use AF K Lotion in excessive amounts or for a longer time than recommended, as it does not yield quicker or better results, but instead increases the risk of side effects. Seek medical attention if you experience any unusual symptoms.

Diet & Lifestyle Advise

  • To fight inflammation (swelling and redness), eat foods rich in anti-inflammatory properties, such as tomatoes, olive oil, plenty of green, leafy vegetables, strawberries, cherries, blueberries, bell peppers, sweet potatoes, almonds, avocados, and wheat germ.
  • Take fish oil supplements, as they help suppress flare-ups of dermatitis triggered by allergies and boost overall immunity.
  • Regularly wash the affected areas with a mild shampoo.
  • Use conditioners, shampoos and other products containing tea tree oil as they might help to relieve itching.
  • Avoid styling hair sprays and gels during a flare.
  • Avoid alcohol-based products as they trigger a reaction.

Health Queries

Have a query?

How Soon It Starts Working

  • The time required for AF K Lotion to start to work: AF K Lotion ideally shows its action within 2 to 4 weeks of consistent use. 
  • The time for which the effects of AF K Lotion last: The duration of action for AF K Lotion is clinically unknown.

What if you forget to take AF K Lotion

If you miss a dose, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the next dose at the regular time.

Storage

• Store in a cool and dry place away from sunlight.• Keep AF K Lotion out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • If you are known to be allergic to AF K Lotion or any other medicines, please tell your doctor.
  • Avoid contact of AF K Lotion with nose, mouth, or eyes. In case AF K Lotion comes in contact with these areas accidentally, rinse with water thoroughly.
  • Do not swallow AF K Lotion. In case of accidental swallowing, contact a nearby poison control centre or consult a doctor immediately.
  • If you are pregnant or a nursing mother, it is advised to consult a doctor before using AF K Lotion.
  • AF K Lotion is not recommended for children below 12 years, as the safety and effectiveness have not been established.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: No interactions were found or established.

Drug-Food Interactions: No interactions were found or established.

Drug-Disease Interactions: No interactions were found or established.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

[ANTIFUNGALS - TOPICAL]

FAQs

AF K Lotion belongs to a class of dermatological medication called 'antifungal,' primarily used to treat dandruff, localised tinea versicolor of the scalp, and seborrheic dermatitis.
AF K Lotion contains Ketoconazole and zinc pyrithione. Ketoconazole is an antifungal agent that disrupts the fungal cell membrane, preventing the growth of dandruff-causing fungi, while zinc pyrithione is a broad-spectrum antimicrobial that inhibits fungal and bacterial growth, reducing scalp irritation and flaking. Their combined action helps control scalp infections, reduce inflammation, and restore scalp health.
Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close, direct contact until the infection is clear and avoid sharing things with the infected person, as this can also spread the infection.
Yes, you may be advised to stop using cream or lotion containing steroids such as hydrocortisone or betamethasone before using AF K Lotion. However, inform your doctor if you are using any steroidal creams or lotions before using this lotion so that the dose of steroidal cream may be reduced gradually to avoid flaring up the condition while using it.
It is recommended that you use AF K Lotion for as long as your doctor has prescribed it. However, if the condition persists or worsens after 2 to 4 weeks of treatment with AF K Lotion, please consult a doctor.
No, you are not recommended to stop using AF K Lotion without consulting your doctor, as it may cause recurring infections. Therefore, take AF K Lotion for as long as your doctor has prescribed it, and if you experience any difficulty while taking it, please consult your doctor.
Yes, it is for use on the scalp.
The common side effects of AF K Lotion may include itching, redness, irritation, or a burning sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). Keto Plus Shampoo Ketoconazole Bp 2 And Zinc Pyithione 1 Pil [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. DailyMed Database. Druginfo.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026] Check here
  3. U.S. Food and Drug Administration (FDA). Ketoconazole Usp 20 Mg And Zinc Pyrithione Suspension 48 Dermazole Plus Kusum Healthcare Pvt. Ltd [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  4. Pinewood Healthcare. Ketoconazole 2% w/w Shampoo – Summary of Product Characteristics [Internet]. Dublin: Pinewood Healthcare; [Accessed on 2025 Sep 17] Check here
  5. Daily med. Pyrithione zinc shampoo. [Revised in November 2021] [Accessed on 21st April 2026] Check here
  6. Central Drugs Standard Control Organization (CDSCO). List of New Drugs Approved in the Year 2025 Till Date [Internet]. New Delhi: CDSCO; [Accessed on 2025 Sep 17] Check here
  7. Alkem Laboratories Ltd. Dandrop Shampoo 2% (Ketoconazole & Zinc Pyrithione) – Product Information [Internet]. Mumbai: Alkem Laboratories Ltd.; [Accessed on 2025 Sep 17]Check here

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - AFK0002

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