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compositionComposition:METHYLDOPA-500MG
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Alphadopa 500 mg Tablet is used to treat Hypertension (mild, moderate, or severe). It contains Methyldopa, a vasodilator. It works by relaxing the blood vessels so that blood can flow more easily throughout the body. Thus, it effectively treats blood pressure. Common side effects of this medication include headaches, muscle weakness, swollen ankles or feet, upset stomach, vomiting, diarrhoea, gas, and dry mouth.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METHYLDOPA-500MG

Manufacturer/Marketer :

Wockhardt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Alphadopa 500 mg Tablet

Alphadopa 500 mg Tablet is an oral prescription medication used to treat high blood pressure (hypertension). By keeping your blood pressure within a normal range, it helps lower your risk of serious cardiovascular problems like strokes and heart attacks.

To get the best results, you must take Alphadopa 500 mg Tablet consistently every day as directed by your doctor. You can take this medication with or without food, but it is best to take it the same way each time. Combining this medicine with a low-salt diet and regular light exercise can significantly improve your blood pressure control.

While taking Alphadopa 500 mg Tablet , you may experience mild side effects like drowsiness or dizziness, especially when first starting. However, if you notice signs of liver damage, such as yellow skin or eyes, dark urine, or unusual tiredness, you must contact your healthcare provider immediately.

Do not take this if you have active liver disease or a history of liver problems caused by this medication. Before starting, tell your doctor if you have kidney disease, a history of depression, or a rare tumour called pheochromocytoma.

This medicine can interact with alcohol, which may increase drowsiness and cause your blood pressure to drop too low. It is widely used in pregnant individuals, but if you are pregnant, breastfeeding, or elderly, you should discuss your specific treatment plan with your doctor or pharmacist.

Uses of Alphadopa 500 mg Tablet

Alphadopa 500 mg Tablet is used to treat high blood pressure (hypertension). The detailed uses of Alphadopa 500 mg Tablet are as follows:

  • High blood pressure (hypertension): Alphadopa 500 mg Tablet helps by relaxing the blood vessels, allowing blood to flow more easily and reducing the workload on your heart.
  • High blood pressure in pregnancy (gestational hypertension): This medication is commonly prescribed to manage elevated blood pressure safely during pregnancy to protect both the mother and the baby.

Key Benefits

Alphadopa 500 mg Tablet provides reliable, long-term protection against the hidden dangers of high blood pressure. Because hypertension often has no symptoms, the primary benefit of this medication is preventing life-threatening complications before they occur.

  • Reduces cardiovascular risks: By keeping your blood pressure stable, it significantly lowers your chances of experiencing a stroke, heart attack, or kidney failure.
  • A trusted choice during pregnancy: It provides a well-studied, safer alternative for managing high blood pressure during pregnancy, helping to ensure a safer delivery.
  • Gentle on heart rate: Unlike some other blood pressure medications, it lowers blood pressure without drastically altering your normal resting heart rate.

Directions for Use

  • Alphadopa 500 mg Tablet can be taken with or without food as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Alphadopa 500 mg Tablet as a whole with a glass of water.
  • Do not break, chew or crush Alphadopa 500 mg Tablet .

How Alphadopa 500 mg Tablet Works

Alphadopa 500 mg Tablet contains methyldopa, which works centrally, meaning it acts directly on your brain and nervous system to control your blood pressure. It belongs to a group of medicines known as central alpha-2 adrenergic agonists. When you take Alphadopa 500 mg Tablet , it stimulates specific receptors in your brain that send signals to your nervous system. These signals tell your blood vessels to relax and widen. Once the blood vessels open up, blood can flow through them more freely. This action lowers the overall pressure in your circulatory system and makes it much easier for your heart to pump blood throughout your body.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Alphadopa 500 mg Tablet . The antihypertensive effect of methyldopa may be amplified when combined with alcohol.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before taking Alphadopa 500 mg Tablet . Your doctor will weigh the benefits and risks before prescribing Alphadopa 500 mg Tablet . It should be used under close medical supervision to treat hypertension during pregnancy.

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Breast Feeding

Caution

Methyldopa appears in breast milk. The use of the drug in breastfeeding mothers requires that anticipated benefits be weighed against possible risks. Hence, if you are a nursing mother, inform your doctor before receiving Alphadopa 500 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Alphadopa 500 mg Tablet may cause sedation and sleepiness. Hence, do not drive or operate machines while on treatment with this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Alphadopa 500 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before taking Alphadopa 500 mg Tablet . Your doctor may adjust the dose of this medicine based on your condition.

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Children

Consult your doctor

Limited information is available regarding the usage of Alphadopa 500 mg Tablet in children, so please consult a doctor for more information.

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Heart

Caution

Alphadopa 500 mg Tablet can be used in heart patients, especially for high blood pressure, but it may cause bradycardia or worsen heart failure. Medical supervision and regular monitoring are essential for safe use.

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Geriatrics

Caution

Geriatric patients can take Alphadopa 500 mg Tablet , but it may be more sensitive to side effects like dizziness, fatigue, or low blood pressure. Careful dose adjustment and regular monitoring are important to ensure safe use.

What if I have taken an overdose of Alphadopa 500 mg Tablet

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose may include extreme drowsiness, severe dizziness, slow heart rate, or fainting. Do not wait for symptoms to worsen before seeking help.

Diet & Lifestyle Advise

  • Reduce your sodium intake: Avoid high-salt foods and processed meals. Lowering your salt intake directly helps Alphadopa 500 mg Tablet control your blood pressure.
  • Stand up slowly: This medicine can cause dizziness when you change positions. Take your time when rising from a sitting or lying position to prevent falls.
  • Monitor your blood pressure: Keep a daily log of your blood pressure readings at home and share them with your doctor at your next visit.
  • Stay hydrated: Drink plenty of water throughout the day, unless your doctor has advised you to limit fluids due to a kidney or heart condition.
  • Limit alcohol consumption: Alcohol can increase the dizzying and sedating effects of this medicine, making you feel more lightheaded.
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How Soon It Starts Working

The time required for Alphadopa 500 mg Tablet to start to work: Alphadopa 500 mg Tablet ideally starts to show its action within 3-4 hours of administration. The time for which the effects of Alphadopa 500 mg Tablet last: Alphadopa 500 mg Tablet effect lasts for 12-24 hours.

What if you forget to take Alphadopa 500 mg Tablet

If you miss a dose of Alphadopa 500 mg Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, talk to your doctor or pharmacist.

Storage

• Store Alphadopa 500 mg Tablet tablets at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Expect regular blood tests: Your doctor will likely order blood tests, including liver function tests and blood cell counts, during the first few months of your treatment to ensure the medicine is safe for you.
  • Avoid driving initially: Do not drive, operate heavy machinery, or perform tasks requiring mental alertness until you know how Alphadopa 500 mg Tablet affects you, as it commonly causes sleepiness.
  • Inform your surgical team: If you need any surgery or dental procedures, tell your doctor or dentist beforehand that you are taking Alphadopa 500 mg Tablet , as it can affect how you respond to anaesthetics.
  • Watch for fever: A fever during the first few weeks of starting this medicine can be a sign of an allergic or liver reaction. Report any unexplained fever to your doctor immediately.
  • Do not stop suddenly: Suddenly stopping this medication can cause a dangerous rebound spike in blood pressure. Always consult your doctor before making changes.

Drug-Drug Interactions

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  • Iron supplements or multivitamins containing iron: Taking these at the same time can significantly reduce how much Alphadopa 500 mg Tablet your body absorbs. Space these products at least 2 hours apart.
  • Lithium: Alphadopa 500 mg Tablet can increase the levels of lithium in your body, raising the risk of lithium toxicity.
  • Other blood pressure medications: Combining this medicine with other blood pressure-lowering agents can cause your blood pressure to drop too low, leading to severe dizziness.
  • Monoamine oxidase inhibitors (MAOIs): Combining these medicines can lead to severe and unpredictable blood pressure changes.

Drug-Drug Interactions

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How does the drug interact with Alphadopa 500 mg Tablet:
Taking Alphadopa 500 mg Tablet and Metoclopramide together can decrease the levels and effects of Alphadopa 500 mg Tablet.

How to manage the interaction:
Taking Metoclopramide with Alphadopa 500 mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Alphadopa 500 mg Tablet:
Taking Safinamide and Alphadopa 500 mg Tablet together can increase the risk of high blood pressure or brain related problems.

How to manage the interaction:
Taking Safinamide with Alphadopa 500 mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately If you experience symptoms such as severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Alphadopa 500 mg Tablet:
Combining Tizanidine and Alphadopa 500 mg Tablet can lower your blood pressure.

How to manage the interaction:
Taking Tizanidine and Alphadopa 500 mg Tablet together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like dizziness, or feeling like you might pass out, especially when getting up from a sitting or lying position, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Alphadopa 500 mg Tablet:
Coadministration of Alphadopa 500 mg Tablet and Carvedilol can reduce the effects of Alphadopa 500 mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Alphadopa 500 mg Tablet and Carvedilol, but it can be taken if prescribed by a doctor. However, if you notice any dizziness, headache, or palpitations, consult your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Alphadopa 500 mg Tablet:
Co-administration of Alphadopa 500 mg Tablet with Labetalol, the effectiveness of Alphadopa 500 mg Tablet might be reduced.

How to manage the interaction:
Although taking Labetalol and Alphadopa 500 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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  • Alcohol: Consuming alcohol while taking this medicine can worsen drowsiness, dizziness, and lightheadedness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

No. Do not stop taking Alphadopa 500 mg Tablet without consulting your doctor, even if your blood pressure is normal or you feel well. High blood pressure often has no symptoms, and stopping the medicine suddenly may cause your blood pressure to rise again, increasing the risk of serious complications. Continue taking Alphadopa 500 mg Tablet for as long as prescribed. If you have concerns or experience side effects, speak with your doctor before making any changes to your treatment.
Yes, it is one of the most widely studied and commonly prescribed medications for managing high blood pressure during pregnancy. However, you should always discuss the risks and benefits of your specific situation with your healthcare provider. Talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medicine. Alcohol can significantly increase side effects like dizziness and extreme drowsiness. Talk to your doctor.
Yes, drowsiness and sleepiness are very common side effects of Alphadopa 500 mg Tablet , particularly when you first start taking it or when your dose is increased. This usually improves over time. Talk to your doctor.
Sucking on sugarless hard candies, chewing sugarless gum, or drinking water frequently can help relieve dry mouth. If dry mouth persists or becomes severe, talk to your doctor.
In some cases, Alphadopa 500 mg Tablet can affect your mood and has been known to cause or worsen depression. If you notice changes in your mood, feelings of sadness, or anxiety, contact your healthcare provider. Talk to your doctor.
Yes, your doctor will likely request regular blood tests to monitor your liver function and red blood cell counts, especially during the first few months of starting the medicine. Talk to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India.
Other Info - ALP0187
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