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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Amace Tablet is used to treat hypertension (high blood pressure). It contains Amlodipine and Enalapril, which works by relaxing and widening blood vessels and lowering the blood pressure. Also, it improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. In some cases, it may cause side effects such as blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck, and trunk), dizziness, headache, and swelling of the ankles or feet. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amace Tablet

Amace Tablet belongs to the class of 'anti-hypertensive drugs' primarily used to treat hypertension (high blood pressure). Hypertension is a medical condition in which the blood exerts high pressure (force exerted by circulating blood) against the blood vessel's walls. This condition makes the heart work harder in pumping blood to the whole body. Hypertension can cause severe health complications, including stroke, heart failure, heart attack, and kidney failure.

The Amace Tablet contains two medicines: Amlodipine (calcium channel blocker) and Enalapril (angiotensin-converting enzyme inhibitor). Amlodipine works by relaxing blood vessels to pass through them, thereby lowering the blood pressure easily. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. On the other hand, Enalapril works by relaxing and widening the blood vessels, making it easier for the heart to pump blood throughout the body, thereby lowering blood pressure. 

Take Amace Tablet as prescribed by your doctor. You are advised to take Amace Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck, and trunk), dizziness, headache, and swelling of the ankles or feet. Most of these side effects of Amace Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, please reach out to your doctor.

Do not stop taking Amace Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Regular monitoring of blood pressure, electrolyte levels, and kidney functioning is advised while taking Amace Tablet . Inform your doctor if you are suffering from kidney, liver, or heart diseases. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Let your doctor know if you use any prescription and non-prescription medications you are taking, including vitamins, before starting Amace Tablet . If you are pregnant or breastfeeding, please tell your doctor so that the dosage of Amace Tablet can be prescribed accordingly. 

Uses of Amace Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

• Take Amace Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Amace Tablet treats hypertension (high blood pressure), and consists of Amlodipine and Enalapril. Amlodipine is a 'calcium channel blocker,' primarily treats high blood pressure, Prinzmetal's or variant angina (chest pain), and other conditions caused by coronary artery disease. It relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen. Amlodipine also improves a person's tolerance to exercise and keeps the blood pressure at acceptable levels. Enalapril is an 'Angiotensin-Converting Enzyme (ACE) Inhibitor.' It relaxes and widens the blood vessels making it easier for the heart to pump blood throughout the body, thereby lowering blood pressure.  

How Amace Tablet Works

Amace Tablet contains two medicines: Amlodipine (calcium channel blocker) and Enalapril (angiotensin-converting enzyme inhibitor). Amlodipine works by relaxing blood vessels to pass through them, thereby lowering the blood pressure easily. It also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. On the other hand, Enalapril works by relaxing and widening the blood vessels, making it easier for the heart to pump blood throughout the body, thereby lowering blood pressure.

Storage

Keep Amace Tablet out of the sight and reach of children.

What if I have taken an overdose of Amace Tablet

Do not take more than the prescribed dose of Amace Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Amace Tablet if you are allergic to Amace Tablet or any of its components. Please inform your doctor if you are using any prescription and non-prescription medications you are taking, including vitamins, before starting Amace Tablet . Let your doctor know if you have any history of severe heart, kidney, or liver diseases, high potassium levels (hyperkalemia), bone marrow suppression, and aortic stenosis (heart valve problem). It is essential to let your doctor know if you are a breastfeeding mother before using Amace Tablet since Amlodipine may pass into the breast milk. Enalapril is not recommended during pregnancy since it has harmful effects on the unborn baby. Please ask your doctor if you plan to conceive or are pregnant before using Amace Tablet . Amace Tablet can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Amace Tablet:
Using Amace Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Amace Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amace Tablet:
Using aliskiren together with Amace Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking Amace Tablet with aliskiren is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Amace Tablet:
Using Amace Tablet and mitotane together may drastically lower Amace Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amace Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amace Tablet:
Using Amace Tablet and phenytoin together may drastically lower Amace Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Amace Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Amace Tablet:
When Amace Tablet is taken with Fosphenytoin, it may decrease the blood levels of Amace Tablet, which may make Amace Tablet less effective.

How to manage the interaction:
Although taking Amace Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Amace Tablet:
Using phenobarbital and Amace Tablet may drastically lower Amace Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Amace Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Amace Tablet:
Coadministration of Amace Tablet and Rifapentine may significantly reduce the blood levels of Amace Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Amace Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amace Tablet:
Using Amace Tablet and rifabutin together may lower Amace Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amace Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amace Tablet:
Coadministration of Amace Tablet and carbamazepine together may significantly reduce Amace Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amace Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amace Tablet:
Coadministration of Ceritinib together with Amace Tablet can slow heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Amace Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a body mass index (BMI) between 19.5 and 24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, use only one serving for women and two servings for men.

  • Quit smoking to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress.

  • Monitor your blood pressure daily, and if you notice any fluctuations frequently, please contact your doctor immediately.

  • Try including heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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Alcohol

Caution

Alcohol may lower your blood pressure. It would help if you avoided or limit consuming alcohol.

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Pregnancy

Unsafe

Enalapril in Amace Tablet is a pregnancy D category drug and is not recommended during pregnancy since it causes harmful effects on the baby. However, it is advised to seek medical advice before using Amace Tablet if you plan to conceive or pregnant.

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Breast Feeding

Caution

There are limited studies on how Amace Tablet affects the breastfed infants. However, Amlodipine in Amace Tablet passes into the breast milk during breastfeeding. Please consult your doctor before using Amace Tablet if you are a lactating mother.

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Driving

Caution

Amace Tablet may cause side effects due to lowering of the blood pressure such as dizziness or tiredness. If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using Amace Tablet . Amace Tablet is to be administered with caution in patients with severe hepatic impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using Amace Tablet . Amace Tablet is primarily eliminated by the kidney and can be accumulated in patients with renal impairment.

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Children

Unsafe

Amace Tablet is not recommended for use in children as the efficacy and safety have not been established.

Have a query?

FAQs

Amace Tablet belongs to the class of 'anti-hypertensive drugs' primarily used to treat hypertension (high blood pressure). It relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. It also treats chest pain by improving the blood supply to the heart muscle to receive more oxygen.

Amlodipine in Amace Tablet can cause ankle swelling upon long-term use. Please try to keep your feet at an elevated position when sitting for long hours. If the problem persists, please consult your doctor and do as advised.

Amace Tablet may increase blood potassium levels in people with diabetes, poor kidney function, and patients using potassium-sparing diuretics or taking potassium supplements. Please consult your doctor before taking Amace Tablet if you have diabetes.

Even though your blood pressure becomes normal after using Amace Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.

Amace Tablet can cause dizziness as one of its side effects. If you feel dizzy, try getting up slowly from a sitting or lying position. If your dizziness is severe or unmanageable, please seek medical advice.

Before surgery, you should inform your doctor that you are taking Amace Tablet as it can reduce your blood pressure when used along with anesthesia which is given before a major operation.

Amace Tablet treats hypertension (high blood pressure) and consists of Amlodipine (calcium channel blocker) and Enalapril (angiotensin-converting enzyme inhibitor). Amlodipine relaxes blood vessels so that blood passes through them easily, thereby lowering blood pressure. Enalapril relaxes and widens the blood vessels, making it easier for the heart to pump blood throughout the body, thereby lowering the raised blood pressure.

Amace Tablet is not primarily a painkiller. It is a medication used to treat hypertension (high blood pressure) and contains a combination of amlodipine and enalapril.

If you stop taking Amace Tablet , your blood pressure may increase, and your condition may worsen. Consult your doctor before stopping or changing your treatment plan to ensure your blood pressure remains controlled.

The optimal timing for taking Amace Tablet is typically in the morning, as it helps to maintain blood pressure control throughout the day. However, following your doctor's specific instructions regarding the best time to take your medication is essential.

If you forgot a dose of Amace Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose of Amace Tablet to compensate for the missed dose.

When taking Amace Tablet , exercising caution and monitoring your health is crucial. Inform your doctor about any pre-existing kidney or liver disease, diabetes, or heart conditions to ensure safe treatment. Regularly check your blood pressure and kidney function, and be aware of signs of low blood pressure, such as dizziness or fainting. Additionally, report any unusual symptoms, like swelling or difficulty breathing, and limit your intake of salt, potassium-rich foods, and certain medications. By being proactive and following these guidelines, you can minimize potential risks and maximize the benefits of your treatment.

Avoid consumption of alcohol while taking Amace Tablet . Alcohol can increase the risk of side effects such as dizziness, low blood pressure, and heartburn. Additionally, combining alcohol with this medication may reduce its effectiveness in controlling your blood pressure.

Taking more than the prescribed dose of Amace Tablet leads to an overdose. Symptoms of overdose include dizziness, light-headedness or fainting and an irregular heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Take Amace Tablet as prescribed by your doctor; your doctor will evaluate your health condition and suggest whether you can take Amace Tablet every day or not. Therefore, follow your doctor's instructions regarding the dosage and frequency.

The common side effects of Amace Tablet are blurred vision, sweating, confusion, tiredness, stomach upset, flushing (sense of warmth in the face, ears, neck, and trunk), dizziness, headache, and swelling of the ankles or feet. Please consult your doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - AMA0013

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