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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Amifru Plus Tablet is a combination medicine used in the treatment of Oedema (swelling) and hypertension (high blood pressure). This medicine contains amiloride and torsemide, which works by reducing the excess fluid levels in the body and thus reduces swelling. Common side effects include dehydration, electrolyte disturbances (calcium, magnesium, and sodium), headache, nausea, or dizziness
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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Amifru Plus Tablet

Amifru Plus Tablet belongs to a class of medicine called 'diuretics (water pills) primarily used to remove excess water from the body. It also keeps the potassium level in the bloodstream stable and prevents hypertension (high blood pressure caused by oedema/fluid retention). Oedema, also known as fluid overload, occurs due to the build-up of fluid in spaces between the cells. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

Amifru Plus Tablet is a combination that includes Amiloride and Torsemide. Amiloride and Torsemide are both diuretics that are used to treat resistant oedema (fluid overload) caused by pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Amifru Plus Tablet works by increasing the amount of urine excreted by the kidneys. It effectively treats oedema (swelling) caused by heart, liver, kidney, or lung disease by reducing excess fluid levels in the body. This reduces the workload on the heart and makes it more efficient at pumping blood throughout the body. As a result, it also helps lower high blood pressure, lowering the chances of a future heart attack, stroke, or angina (chest pain).

You can take Amifru Plus Tablet with or without food. Take it preferably during the day to avoid frequent urination at night. Swallow it as a whole with water. It should not be chewed, crushed, or broken. Based on your medical condition, your doctor will advise on how frequently you should take Amifru Plus Tablet . In some cases, you may experience dehydration, electrolyte disturbances (potassium and sodium), headache, nausea, or dizziness. Most of the side effects do not necessitate medical attention and fade away over time. However, if the side effects persist, consult your doctor.

Inform your doctor if you have kidney, liver, or heart disease. Please notify your doctor if you are pregnant or breastfeeding. Inform your doctor if you are taking any other medications or if you are allergic to Amifru Plus Tablet . Amifru Plus Tablet is not recommended for children below 12 years of age. Amifru Plus Tablet may cause drowsiness, so drive with caution. Avoid alcohol intake as it might cause increased drowsiness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Amifru Plus Tablet

Treatment of Oedema (fluid overload)

Directions for Use

• Amifru Plus Tablet can be taken with or without food, as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication. Avoid taking this medication within 4 hours of going to bed to avoid nighttime urination.• Swallow Amifru Plus Tablet as a whole with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Amifru Plus Tablet is a combination that includes Amiloride and Torsemide. Amiloride and Torsemide are both diuretics that are used to treat resistant oedema (fluid overload) caused by pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Amifru Plus Tablet works by increasing the amount of urine excreted by the kidneys. It effectively treats oedema (swelling) caused by heart, liver, kidney, or lung disease by reducing excess fluid levels in the body. This reduces the workload on the heart and makes it more efficient at pumping blood throughout the body. As a result, it also helps lower high blood pressure, lowering the chances of a future heart attack, stroke, or angina (chest pain).

How Amifru Plus Tablet Works

Amifru Plus Tablet is a combination that includes Amiloride and Torsemide. Amiloride and Torsemide are both diuretics that are used to treat resistant oedema (fluid overload) caused by pulmonary hypertension (high blood pressure in the lungs), heart failure, and hepatic cirrhosis (chronic liver damage). Amifru Plus Tablet works by increasing the amount of urine excreted by the kidneys. It effectively treats oedema (swelling) caused by heart, liver, kidney, or lung disease by reducing excess fluid levels in the body. This reduces the workload on the heart and makes it more efficient at pumping blood throughout the body. As a result, it also helps lower high blood pressure, lowering the chances of a future heart attack, stroke, or angina (chest pain).

Storage

Keep Amifru Plus Tablet out of the sight and reach of children.

What if I have taken an overdose of Amifru Plus Tablet

Take Amifru Plus Tablet only as prescribed by the doctor. Do not exceed the recommended dose as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

People who are allergic to Amifru Plus Tablet , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, should not take Amifru Plus Tablet . Furthermore, it is contraindicated in patients with low blood pressure (hypotension), cardiogenic shock (sudden cessation of blood flow to the heart), and aortic stenosis (heart valve problem). Talk to your doctor before taking Amifru Plus Tablet if you are pregnant or breastfeeding. Before using Amifru Plus Tablet , any electrolyte dehydration and acid-base disturbances must be corrected. Take no additional potassium supplements or potassium-rich foods like bananas and broccoli with Amifru Plus Tablet , as this may result in an excessive increase in blood potassium levels (hyperkalemia). Please take Amifru Plus Tablet at least 4 hours before going to bed to avoid night-time urination.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Amifru Plus Tablet:
Co-administration of Amifru Plus Tablet can make Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Desmopressin and Amifru Plus Tablet together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Coadministration of Amifru Plus Tablet with Drospirenone may increase potassium levels in the blood.

How to manage the interaction:
Taking Amifru Plus Tablet with Drospirenone may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes. Do not stop using any medications without talking to a doctor.
How does the drug interact with Amifru Plus Tablet:
Coadministration of Amifru Plus Tablet with Spironolactone may increase potassium levels in the blood.

How to manage the interaction:
Taking Amifru Plus Tablet with Spironolactone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
How does the drug interact with Amifru Plus Tablet:
Co-administration of Amikacin with Amifru Plus Tablet may increase this risk of side effects.

How to manage the interaction:
Although taking amikacin and Amifru Plus Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as ringing in the ears, irregular urination, vomiting, weakness, or muscle cramps. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Taking Amifru Plus Tablet together with lithium may increase the effects of lithium.

How to manage the interaction:
Taking lithium with Amifru Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden diarrhea, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Co-administration of tobramycin with Amifru Plus Tablet increases the risk of toxicity.

How to manage the interaction:
Although taking tobramycin and Amifru Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Co-administration of neomycin with Amifru Plus Tablet can increase the risk of toxicity.

How to manage the interaction:
Although taking neomycin and Amifru Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as hearing loss, ringing in the ears, vertigo, and kidney problems, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Co-administration of amiodarone with Amifru Plus Tablet can increase the risk the risk of irregular heart rhythm.

How to manage the interaction:
Taking amiodarone with Amifru Plus Tablet together is recommended to avoid as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, sweating, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Taking Amifru Plus Tablet together with streptomycin may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking streptomycin and Amifru Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Amifru Plus Tablet:
Co-administration of probenecid with Amifru Plus Tablet can increase the risk of side effects.

How to manage the interaction:
Although taking probenecid and Amifru Plus Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Choose a diet high in whole grains, fruits and vegetables, and low-fat dairy products.
  • Limit your daily sodium chloride (table salt) intake to 2300 mg per day or less than 1500 mg for most adults.
  • If you drink alcohol, limit yourself to one serving for women and two servings for men.
  • Quitting smoking is the most effective way to reduce your risk of heart disease.
  • Include heart-healthy omega 3 fatty acid-containing foods and beverages in your daily diet. To lower your blood pressure, you can also use low-fat cooking oils such as olive oil, soybean oil, canola oil, and coconut oil.

Habit Forming

No

Therapeutic Class

DIURETIC

Amifru Plus Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

You are recommended not to consume alcohol along with Amifru Plus Tablet to avoid unpleasant side effects.

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Pregnancy

Unsafe

Amifru Plus Tablet must not be taken during pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Breast-feeding must be avoided during treatment with Amifru Plus Tablet . Please consult your doctor if you have any concerns.

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Driving

Caution

It is not recommended to drive after taking Amifru Plus Tablet as it may occasionally cause drowsiness due to orthostatic hypotension (sudden drop in blood pressure on standing from lying position).

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Liver

Caution

Amifru Plus Tablet should be used with caution, particularly if you have a history of liver diseases/conditions. Depending on your current kidney condition, your doctor may adjust your dose.

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Kidney

Caution

Amifru Plus Tablet should be used with caution, particularly if you have a history of kidney diseases/conditions. Depending on your current kidney condition, your doctor may adjust your dose.

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Children

Unsafe

Amifru Plus Tablet is not recommended for children below 12 years of age.

Have a query?

FAQs

Amifru Plus Tablet belongs to a class of medicine called 'diuretics (water pills) primarily used to remove excess water from the body. It also keeps the potassium level in the bloodstream stable and prevents hypertension (high blood pressure caused by oedema/fluid retention).

Amifru Plus Tablet works by increasing the amount of urine excreted by the kidneys. It effectively treats oedema (swelling) caused by heart, liver, kidney, or lung disease by reducing excess fluid levels in the body.

Fluid retention or overload is a medical term. Oedema causes swelling in the legs, hands, and other body parts, which raises blood pressure. If it does not go away, please see your doctor right away.

The main side effect of Amifru Plus Tablet is that you pee (urinate) more frequently than usual. Most people need to pee within 30 minutes of taking Amifru Plus Tablet , and then again within a few hours. If you take Amifru Plus Tablet before going to bed, you may have to wake up several times during the night to urinate. To avoid this, take it preferably during the day to avoid frequent urination at night.

Yes, Amifru Plus Tablet has been linked to dehydration (excessive loss of fluids). Dry mouth, decreased urine output, excessive thirst, and hypotension may occur in the patient (decreased blood pressure). As a result, please increase your fluid intake to avoid dehydration.

Yes, Amifru Plus Tablet can cause hyperkalemia (high potassium levels), especially in patients with kidney problems or if you are taking potassium supplements in addition to Amifru Plus Tablet . Please keep an eye on your electrolyte levels regularly to avoid an increase in blood potassium levels.

Amifru Plus Tablet has the potential to cause orthostatic hypotension. This is low blood pressure, which causes dizziness or lightheadedness when you stand up after sitting or lying down. This could be more common when you first start taking this medication. You can avoid this by slowly rising. Consult your doctor if the symptoms persist.

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - AMI0425

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