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compositionComposition:ALLOPURINOL-300MG
prescriptionPrescription Medicine
Apllinol 300mg Tablet 10's

Apllinol 300mg Tablet 10's is used to reduce blood uric acid levels. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, and bladder stones. It contains Allopurinol, which stops uric acid production in the body and prevents crystal buildup. Common side effects include stomach upset, diarrhoea, skin rash, and drowsiness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALLOPURINOL-300MG

Manufacturer/Marketer :

Syntonic Life Sciences

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Apllinol 300mg Tablet 10's

Apllinol 300mg Tablet 10's is primarily used to reduce blood uric acid levels. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, and bladder stones.

Apllinol 300mg Tablet 10's contains allopurinol, which works by blocking the action of xanthine oxidase, the enzyme responsible for the production of uric acid. It inhibits uric acid formation in the body and prevents crystal formation, making it effective in managing gout and kidney/bladder stones.

Take Apllinol 300mg Tablet 10's exactly as prescribed by your doctor. Swallow it whole with a glass of water, and do not crush or chew it. Common side effects of Apllinol 300mg Tablet 10's include stomach upset, diarrhoea, skin rash, and drowsiness. Please talk to your doctor if any of these side effects persist.

Do not take Apllinol 300mg Tablet 10's if you are allergic to any of its ingredients. If you are pregnant, planning to get pregnant, or breastfeeding, consult your doctor for advice before using Apllinol 300mg Tablet 10's. Seek medical advice immediately if you notice unexplained weight loss while on treatment with Apllinol 300mg Tablet 10's.

Uses of Apllinol 300mg Tablet 10's

Apllinol 300mg Tablet 10's is used to decrease uric acid levels in the body. The detailed uses of Apllinol 300mg Tablet 10's are as follows:

  • Long-term management of gout: Apllinol 300mg Tablet 10's effectively prevents and treats gout by stopping the buildup of uric acid crystals in the joints.
  • Prevention of kidney stones: Apllinol 300mg Tablet 10's helps prevent the formation of uric acid kidney stones by lowering uric acid levels in the urine.
  • Prevention of bladder stones: Apllinol 300mg Tablet 10's helps prevent the formation of bladder stones composed of uric acid.

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Directions for Use

  • Take Apllinol 300mg Tablet 10's with food to avoid stomach upset or as advised by a doctor.
  • Recommended to take the medicine once or twice a day or as advised by your doctor.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

  • Apllinol 300mg Tablet 10's is used to reduce serum uric acid levels.
  • It helps prevent and treat gout by stopping the formation and buildup of uric acid crystals in the joints.
  • It decreases urinary uric acid concentration, thereby reducing the risk of kidney stone formation.
  • It helps prevent uric acid from forming stones in the bladder.
  • It lowers uric acid levels in patients undergoing chemotherapy, protecting the kidneys and minimising complications.

How Apllinol 300mg Tablet 10's Works

Apllinol 300mg Tablet 10's contains allopurinol, which works by blocking the action of xanthine oxidase, the enzyme responsible for the production of uric acid. It inhibits uric acid formation in the body and prevents crystal formation, making it effective in managing gout and kidney/bladder stones.

Storage

Store in a cool and dry place away from sunlight
Side effects of Apllinol 300mg Tab
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Take cold water baths avoiding soap.
  • Avoid scratching and scrubbing to prevent infections while itching.
  • Use nets to prevent insects and mosquitoes.
  • Stop using lotions and creams that cause irritation.
  • Avoid alcohol and caffeine intake.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Apllinol 300mg Tablet 10's

Do not take more than the prescribed dose of Apllinol 300mg Tablet 10's, as it may cause adverse effects. If you suspect you have taken an overdose or notice any unusual symptoms, please consult a doctor immediately.

Drug Warnings

  • Do not take Apllinol 300mg Tablet 10's if you are allergic to any of its ingredients.
  • If you are pregnant, planning to get pregnant, or breastfeeding, consult your doctor for advice before using Apllinol 300mg Tablet 10's.
  • Inform your doctor if you have thyroid problems, high blood pressure, or heart, liver, or kidney disease.
  • In rare cases, Apllinol 300mg Tablet 10's may cause bone marrow depression, especially in patients who are already taking other medications with similar effects.
  • Seek medical advice immediately if you notice unexplained weight loss while on treatment with Apllinol 300mg Tablet 10's.
  • Apllinol 300mg Tablet 10's may cause drowsiness, so avoid operating machinery or driving until you are fully alert.

Drug-Drug Interactions

verifiedApollotooltip
AllopurinolDidanosine
Critical
AllopurinolEnalapril
Severe

Drug-Drug Interactions

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AllopurinolDidanosine
Critical
How does the drug interact with Apllinol 300mg Tab:
When Didanosine is taken with Apllinol 300mg Tab, can increase the blood levels of didanosine.

How to manage the interaction:
Taking Apllinol 300mg Tab with Didanosine lead to an interaction, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
AllopurinolEnalapril
Severe
How does the drug interact with Apllinol 300mg Tab:
Coadministration of Apllinol 300mg Tab with Enalapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Apllinol 300mg Tab and Enalapril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not stop using any medications without consulting your doctor.
AllopurinolPerindopril
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Perindopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Apllinol 300mg Tab and Perindopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms, contact your doctor immediately . Do not discontinue any medications without consulting a doctor.
AllopurinolCaptopril
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Captopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Apllinol 300mg Tab and Captopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
AllopurinolLisinopril
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Lisinopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Apllinol 300mg Tab and Lisinopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness chills, sore throat, extreme tiredness, body pains, consult a doctor. Do not discontinue any medications without consulting a doctor.
AllopurinolEntecavir
Severe
How does the drug interact with Apllinol 300mg Tab:
Coadministration of Apllinol 300mg Tab with Entecavir may increase the blood levels of one or both medicines and increase side effects.

How to manage the interaction:
If you are supposed to take Apllinol 300mg Tab and Entecavir together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience increased side effects, contact your doctor.
AllopurinolTrandolapril
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Trandolapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Apllinol 300mg Tab and Trandolapril you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
AllopurinolAzathioprine
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Azathioprine may increase the effects of azathioprine.

How to manage the interaction:
There may be a possibility of interaction between Azathioprine and Apllinol 300mg Tab, but it can be taken if prescribed by a doctor. However, if you experience chills, fever, body pains, sore throat, weakness, muscle pain, mouth sores, easy bruising or bleeding, pale stools, darkened urine, or severe nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor's advice.
AllopurinolDeferiprone
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Deferiprone may increase the risk of dangerous blood clots.

How to manage the interaction:
If you are supposed to take Apllinol 300mg Tab and Deferiprone together, your doctor may advise you to take blood thinner or monitor you more frequently to safely use both medications. However, if you experience shortness of breath, chest pain, coughing up blood, difficulty breathing, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, contact your doctor immediately as these may be signs and symptoms of blood clots. Do not discontinue any medications without consulting a doctor.
AllopurinolFosinopril
Severe
How does the drug interact with Apllinol 300mg Tab:
Co-administration of Apllinol 300mg Tab with Fosinopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Apllinol 300mg Tab and Fosinopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Dietary choices:

  • Avoid or restrict foods high in purine, such as alcohol, fish, meat, and bacon, as they can increase uric acid levels.
  • Avoid soft drinks and fruit juices high in fructose.
  • Maintain a diet rich in fruits, whole grains, vegetables, and low-fat dairy products to support overall health.

Lifestyle habits:

  • Losing weight can help lower uric acid levels in the body.
  • Engage in moderate physical activity daily.
  • Drink plenty of fluids to help flush uric acid from the body.
  • Limit or avoid alcohol and tobacco, as they can raise uric acid levels.
  • Stress may sometimes trigger gout attacks, so activities like yoga and meditation can be helpful.

Habit Forming

No

Therapeutic Class

[GOUT THERAPY]

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Apllinol 300mg Tablet 10's should not be taken along with alcohol, as it increases uric acid levels.

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Pregnancy

Caution

Apllinol 300mg Tablet 10's is a Category C pregnancy drug. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

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Breast Feeding

Unsafe

Apllinol 300mg Tablet 10's is excreted in human breast milk, so it is not recommended during breastfeeding.

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Driving

Unsafe

Apllinol 300mg Tablet 10's may cause some individuals to feel drowsy. Do not drive or operate dangerous machinery if you are affected.

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Liver

Caution

Apllinol 300mg Tablet 10's to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Apllinol 300mg Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Apllinol 300mg Tablet 10's hasn’t been studied and shouldn’t be used in people younger than 18 years to treat gout or kidney stones.

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Heart

Caution

Apllinol 300mg Tablet 10's should be taken with caution in patients with heart disease. Please consult your physician.

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Geriatrics

Caution

Apllinol 300mg Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Apllinol 300mg Tablet 10's.

FAQs

Apllinol 300mg Tablet 10's is used to treat gout (increased uric acid leading to inflammation), kidney stones, and bladder stones. It decreases blood uric acid levels in the body.

Apllinol 300mg Tablet 10's contains allopurinol, which works by blocking the action of xanthine oxidase, the enzyme responsible for the production of uric acid. It stops uric acid formation inside the body and prevents crystal buildup, making it effective in managing gout and kidney/bladder stones.

If you are taking Apllinol 300mg Tablet 10's and it makes you vomit, then your contraceptive pill would not be effective, and it could lead to an unwanted pregnancy. If you are of childbearing age, inform your doctor before starting Apllinol 300mg Tablet 10's and use another form of contraceptive like condoms.

Initially, when you start Apllinol 300mg Tablet 10's, it can increase the number of gout attacks. Please do not stop taking Apllinol 300mg Tablet 10's on having an acute attack (sudden attack) of gout, as it can make the attack even worse. Co-administration with an anti-inflammatory agent (e.g., colchicine) is recommended, and the dose of Apllinol 300mg Tablet 10's should be increased slowly.

Generally, when Apllinol 300mg Tablet 10's is administered to elderly patients (aged> 65 years), the dose is reduced based on the patient’s condition. Also, if you mention all underlining disease you suffer from, which could affect Apllinol 300mg Tablet 10's, the dose will be adjusted accordingly by your doctor.

Yes, Apllinol 300mg Tablet 10's can cause drowsiness in some people. It can even make you feel dizzy or have a problem with coordination. It is advisable to avoid driving or operating machinery to avoid any unpleasant side effects.

No, Apllinol 300mg Tablet 10's is not an anti-inflammatory medicine. It works by inhibiting the enzyme xanthine oxidase, which catalyses the formation of uric acid. It inhibits uric acid formation within the body without affecting essential cellular and systemic mechanisms.

It may take several weeks to lower uric acid levels before you begin to feel better or notice a significant reduction in gout attacks.

Apllinol 300mg Tablet 10's may cause side effects such as nausea, vomiting, diarrhoea, stomach upset, or drowsiness. If these side effects persist or worsen, please consult your doctor.

It is preferable to take Apllinol 300mg Tablet 10's after a meal to prevent stomach upset. But take it at the same time every day to help you remember to take it. However, follow your doctor’s instructions carefully.

You may experience an increase in gout attacks after you have started taking Apllinol 300mg Tablet 10's. However, with several months of therapy, these attacks typically become less severe and shorter. This increase in attacks may be due to the slow dissolution of uric acid crystals, which can cause fluctuations in blood uric acid levels. If you still have any concerns, please consult your physician.

If you consume alcohol while taking Apllinol 300mg Tablet 10's, it increases uric acid levels and worsen your condition. Therefore, avoid alcohol consumption while taking Apllinol 300mg Tablet 10's.

If you forget to take a dose of Apllinol 300mg Tablet 10's, take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for a forgotten dose.

Store Apllinol 300mg Tablet 10's in a cool, dry and dark place. Protect from direct sunlight and moisture. Keep it out of sight and reach of children.

Country of origin

INDIA

Manufacturer/Marketer address

Syntonic Life Sciences, Shri Sai Market, Opposite Hotel Marc Royale Kalka- Zirakpur Highway, Dhakoli, Zirakpur-140603, Punjab, India
Other Info - APL0051

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