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  3. Apretero 125/80 Capsule 1's

Apretero 125/80 Capsule 1's, Pack of 1 CAPSULE
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Apretero 125/80 Capsule is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. It contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

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Composition :

APREPITANT-125MG + APREPITANT-80MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Apretero 125/80 Capsule

Apretero 125/80 Capsule belongs to a class of drugs called anti-emetics. It is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apretero 125/80 Capsule contains Aprepitant. Aprepitant blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

Take Apretero 125/80 Capsule as prescribed. You are recommended to take Apretero 125/80 Capsule for as long as your doctor has advised it. In some cases, Apretero 125/80 Capsule may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, inform your doctor if the side effects persist or worsen.

Please tell your doctor if you are allergic to Apretero 125/80 Capsule or any other medicines. Apretero 125/80 Capsule is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apretero 125/80 Capsule. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apretero 125/80 Capsule. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apretero 125/80 Capsule.

Uses of Apretero 125/80 Capsule

Apretero 125/80 Capsule is used in the treatment of Chemotherapy-induced nausea and vomiting. The detailed uses of Apretero 125/80 Capsule are as follows:<br/>• Chemotherapy-induced nausea and vomiting (CINV) prevention: Apretero 125/80 Capsule helps to prevent nausea and vomiting caused by chemotherapy, which improves patient comfort and quality of life.<br/>• Postoperative nausea and vomiting (PONV) prevention: Apretero 125/80 Capsule can also be used to prevent nausea and vomiting after surgery, which reduces recovery time and complications.<br/>

Directions for Use

• Apretero 125/80 Capsule can be taken with or without food.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Apretero 125/80 Capsule as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Apretero 125/80 Capsule contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.

How Apretero 125/80 Capsule Works

Apretero 125/80 Capsule contains Aprepitant, which blocks a chemical that produces vomiting by acting on the neurological system. Thus, it helps prevent nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Apretero 125/80 Capsule

Since Apretero 125/80 Capsule is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Please tell your doctor if you are allergic to Apretero 125/80 Capsule or any other medicines. Apretero 125/80 Capsule is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apretero 125/80 Capsule. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apretero 125/80 Capsule. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apretero 125/80 Capsule.

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated.
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting.
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Apretero 125/80 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of alcohol with Apretero 125/80 Capsule is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Apretero 125/80 Capsule. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Apretero 125/80 Capsule.

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Driving

Caution

Apretero 125/80 Capsule may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Apretero 125/80 Capsule.

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Liver

Consult your doctor

If you have liver disease, inform your doctor before taking Apretero 125/80 Capsule. Your doctor may monitor your liver condition.

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Kidney

Consult your doctor

If you have kidney problems, inform your doctor before taking Apretero 125/80 Capsule.

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Children

Unsafe

Apretero 125/80 Capsule is not recommended for children below 12 years of age.

Have a query?

FAQs

Apretero 125/80 Capsule is used to treat Chemotherapy-induced nausea and vomiting.

Apretero 125/80 Capsule contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it helps to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.

You are not recommended to take erythromycin with Apretero 125/80 Capsule as it may increase the blood levels and effects of Apretero 125/80 Capsule. Contact your doctor if your condition changes or you experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Apretero 125/80 Capsule.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Apretero 125/80 Capsule. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apretero 125/80 Capsule and for up to 2 months after using Apretero 125/80 Capsule.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - APR0008

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:10 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.11261.pdf
  2. https://www.hpra.ie/img/uploaded/swedocuments/8c35c967-1b86-4814-8cd0-85846ece0a0a.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021549s017lbl.pdf

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