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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Autocort-6 Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

Asmed Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Autocort-6 Tablet

Autocort-6 Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally and is unable to distinguish between foreign cells and native cells. This condition results in an immune system that starts to attack native cells and organs, leading to medical problems like Duchenne muscular dystrophy.

Autocort-6 Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Autocort-6 Tablet binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Autocort-6 Tablet is beneficial in autoimmune diseases and inflammation that cause harm to various organs, especially in joints with arthritis and the skin in psoriasis. Autocort-6 Tablet makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy.

Autocort-6 Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Autocort-6 Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Autocort-6 Tablet can be taken as directed by your doctor, using a measuring cup. Your doctor will recommend how often you take Autocort-6 Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headaches, dizziness, skin rashes, tremors, nervousness, diarrhoea, and fast heartbeats. Most of the side effects of Autocort-6 Tablet do not require medical attention and usually resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, stomach upset, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may occur when the medication is stopped suddenly.

Before starting Autocort-6 Tablet , please inform your doctor that you are allergic or hypersensitive to Autocort-6 Tablet . Extra care is needed when a patient has an existing infection being treated (systemic infection) or has recently received live virus vaccines. A doctor's consultation is required as Autocort-6 Tablet is not safe to use during pregnancy.

Uses of Autocort-6 Tablet

Autocort-6 Tablet used in the treatment of Duchenne muscular dystrophy (DMD). The detailed uses of Autocort-6 Tablet are as follows:
• Treatment of DMD: Autocort-6 Tablet used to treat Duchenne muscular dystrophy by slowing muscle degeneration, preserving strength, and improving mobility.
• Anti-Inflammatory Treatment: Autocort-6 Tablet reduces inflammation and relieves symptoms associated with conditions like arthritis, bursitis, and tendinitis.
• Autoimmune Disorders Management: Autocort-6 Tablet helps to manage autoimmune diseases like lupus and multiple sclerosis by suppressing the immune response.
• Relief from Allergic Reactions: Autocort-6 Tablet provides relief from symptoms of allergic reactions, such as allergic rhinitis, by reducing inflammation and immune response.
• Managing Respiratory Conditions: Autocort-6 Tablet is also involved in managing respiratory conditions like asthma and COPD by reducing airway inflammation.
• Skin Disorders Treatment: Autocort-6 Tablet treats skin conditions like eczema and psoriasis by reducing inflammatory responses.

Directions for Use

Swallow this tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

Medicinal Benefits

Autocort-6 Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Autocort-6 Tablet is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

How Autocort-6 Tablet Works

Autocort-6 Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Autocort-6 Tablet binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Autocort-6 Tablet is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis, skin, and psoriasis. Autocort-6 Tablet makes organ transplantation possible, and treats muscle disorders like Duchenne muscular dystrophy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Autocort-6 Tablet

Most of the side effects of Autocort-6 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Common side effects include upper respiratory tract infection, excessive abdominal fat, runny or stuffy nose, skin redness, irritability, abdominal discomfort or pain, irregular behaviour, fever, back pain, acne, nausea, restlessness, nosebleeds and stretch marks.

What if I have taken an overdose of Autocort-6 Tablet

Do not take more than the prescribed dose of Autocort-6 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney and liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Autocort-6 Tablet .  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Autocort-6 Tablet . Before taking Autocort-6 Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
DeflazacortInfliximab
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Autocort-6 Tablet:
Co-administration of Autocort-6 Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortInfliximab
Severe
How does the drug interact with Autocort-6 Tablet:
Co-administration of Infliximab with Certolizumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Autocort-6 Tablet and Infliximab, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortCarbamazepine
Severe
How does the drug interact with Autocort-6 Tablet:
Taking Carbamazepine with Autocort-6 Tablet may significantly reduce the blood levels of Autocort-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Carbamazepine and Autocort-6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortModafinil
Severe
How does the drug interact with Autocort-6 Tablet:
Taking Modafinil with Autocort-6 Tablet may significantly reduce the blood levels of Autocort-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Modafinil and Autocort-6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortAmprenavir
Severe
How does the drug interact with Autocort-6 Tablet:
Coadministration of Amprenavir with Autocort-6 Tablet can increase the levels of Autocort-6 Tablet in the body.

How to manage the interaction:
Taking Amprenavir with Autocort-6 Tablet together can result in an interaction. It can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, sudden dizziness, lightheadedness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortCertolizumab
Severe
How does the drug interact with Autocort-6 Tablet:
Co-administration of Autocort-6 Tablet with Certolizumab may increase the risk of infections.

How to manage the interaction:
Although there is a possible interaction between Autocort-6 Tablet and Certolizumab, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DeflazacortNevirapine
Severe
How does the drug interact with Autocort-6 Tablet:
Taking Nevirapine with Autocort-6 Tablet may significantly reduce the blood levels of Autocort-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Nevirapine and Autocort-6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortGatifloxacin
Severe
How does the drug interact with Autocort-6 Tablet:
Gatifloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Autocort-6 Tablet.

How to manage the interaction:
Although there is an interaction, Gatifloxacin can be taken with Autocort-6 Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortDexamethasone
Severe
How does the drug interact with Autocort-6 Tablet:
Taking Dexamethasone with Autocort-6 Tablet may significantly reduce the blood levels of Autocort-6 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dexamethasone and Autocort-6 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortRitonavir
Severe
How does the drug interact with Autocort-6 Tablet:
Coadministration of Ritonavir with Autocort-6 Tablet can increase the levels of Autocort-6 Tablet in the body.

How to manage the interaction:
Taking Ritonavir with Autocort-6 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, mood swings, acne, stretch marks, easy bruising, cataracts, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-6MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Autocort-6 Tablet therapy may elevate Autocort-6 Tablet levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Diet & Lifestyle Advise

A patient needs to take extra care of their hygiene and stay away from places or people believed to be a cause of infection, as this drug affects the immune system. Therefore, proper care is necessary.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Autocort-6 Tablet Substitute

Substitutes safety advice
  • Defcort 6 Tablet 10's

    by Others

    13.50per tablet
  • Defza 6 Tablet 10's

    by Others

    14.31per tablet
  • Vellcort 6 mg Tablet 10's

    by AYUR

    14.40per tablet
  • Enzocort 6 Tablet 10's

    by Others

    18.54per tablet
  • Emflav 6 Tablet 10's

    by Others

    15.21per tablet
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Alcohol

Caution

The effect of taking both alcohol and Autocort-6 Tablet may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Autocort-6 Tablet crosses the placenta and doses equivalent to >40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Autocort-6 Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Autocort-6 Tablet .

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Kidney

Caution

Before using Autocort-6 Tablet by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Autocort-6 Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Autocort-6 Tablet .

FAQs

Autocort-6 Tablet is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.

Not recommended in mild allergies. Autocort-6 Tablet is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.

It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.

It is not recommended to be taken Autocort-6 Tablet with alcohol as it may cause stomach bleeding.

No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Autocort-6 Tablet may be used in extreme cases of seasonal allergy.

You should not use Autocort-6 Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Autocort-6 Tablet if you have a compromised immune system, eye problems or weak bones.

Yes, Autocort-6 Tablet is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.

Autocort-6 Tablet is less potent than Prednisone and is usually administered proportionately in higher doses.

No, Autocort-6 Tablet is not a painkiller. It is a steroid medication.

Yes, it can be used to treat kidney stones.

Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.

Yes, it is safe to use Autocort-6 Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.

Common side effects of Autocort-6 Tablet may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Autocort-6 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

Country of origin

India

Manufacturer/Marketer address

139 B , 2nd floor New Colony , GURUGRAM, Gurgaon-122001, Haryana, India
Other Info - AUT0065

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