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  3. Bdpalbo 125MG Capsule 21's

Bdpalbo 125MG Capsule 21's, Pack of 1 CAPSULE
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Bdpalbo 125MG Capsule is an anti-cancer medicine used in the treatment of certain types of breast cancer. This medicine contains palbociclid which works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Common side effects include weakness, loss of appetite, infections and dry skin.
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Composition :

PALBOCICLIB-125MG

Manufacturer/Marketer :

BDR Pharmaceuticals Internationals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Bdpalbo 125MG Capsule

Bdpalbo 125MG Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Bdpalbo 125MG Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Bdpalbo 125MG Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Bdpalbo 125MG Capsule as prescribed. In some cases, Bdpalbo 125MG Capsule may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Bdpalbo 125MG Capsule if you are pregnant or breastfeeding. Bdpalbo 125MG Capsule may cause tiredness, so drive only if you are alert. Bdpalbo 125MG Capsule is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Bdpalbo 125MG Capsule

Treatment of Breast Cancer

Directions for Use

• Bdpalbo 125MG Capsule can be taken with or without food. However, avoid taking it with grapefruit or grapefruit juice.• It is recommended to take Bdpalbo 125MG Capsule once daily or as prescribed by your doctor.• Swallow Bdpalbo 125MG Capsule as a whole with a glass of water.• Do not break, chew, or crush it.

Medicinal Benefits

Bdpalbo 125MG Capsule is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Bdpalbo 125MG Capsule works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Bdpalbo 125MG Capsule nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Bdpalbo 125MG Capsule helps treat breast cancer.

How Bdpalbo 125MG Capsule Works

Bdpalbo 125MG Capsule contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Bdpalbo 125MG Capsule is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer.
Side effects of Bdpalbo 125MG Capsule
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Bdpalbo 125MG Capsule

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, and neutropenia (low neutrophil levels). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Bdpalbo 125MG Capsule . It is advisable to inform the doctor if you are allergic to any of its components. Do not take Bdpalbo 125MG Capsule if you are pregnant or breastfeeding. Bdpalbo 125MG Capsule may cause tiredness, so drive only if you are alert. Bdpalbo 125MG Capsule is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Drug-Drug Interactions

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PalbociclibKetoconazole
Severe
PalbociclibCladribine
Severe

Drug-Drug Interactions

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PalbociclibKetoconazole
Severe
How does the drug interact with Bdpalbo 125MG Capsule:
Coadministration of Ketoconazole and Bdpalbo 125MG Capsule may increase the blood level of Bdpalbo 125MG Capsule.

How to manage the interaction:
Although taking Ketoconazole and Bdpalbo 125MG Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience nausea, vomiting, diarrhea, loss of appetite, mouth sores, hair loss, weakness, pain, numbness, or tingling in the hands and feet, more severely, consult a doctor. Without consulting a doctor, never stop taking any drugs.
PalbociclibCladribine
Severe
How does the drug interact with Bdpalbo 125MG Capsule:
Taking Cladribine with Bdpalbo 125MG Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with Bdpalbo 125MG Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
PalbociclibMorphine
Severe
How does the drug interact with Bdpalbo 125MG Capsule:
Co-administration of Bdpalbo 125MG Capsule with Morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Taking Morphine with Bdpalbo 125MG Capsule can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
PalbociclibPosaconazole
Severe
How does the drug interact with Bdpalbo 125MG Capsule:
When Bdpalbo 125MG Capsule is taken with Posaconazole can increase the blood levels of Bdpalbo 125MG Capsule.

How to manage the interaction:
Although there is an interaction between posaconazole and Bdpalbo 125MG Capsule, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, diarrhea, less desire to eat, mouth sores, hair loss, weakness, pain, numbness, or tingling in the hands and feet contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Bdpalbo 125MG Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is not recommended to use alcohol with Bdpalbo 125MG Capsule . Please consult your doctor if you have any concerns.

bannner image

Pregnancy

Unsafe

Bdpalbo 125MG Capsule is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

bannner image

Breast Feeding

Unsafe

Bdpalbo 125MG Capsule is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

bannner image

Driving

Caution

Bdpalbo 125MG Capsule may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Bdpalbo 125MG Capsule .

bannner image

Liver

Caution

Exercise caution before using Bdpalbo 125MG Capsule in case of established liver disease. Please consult your doctor to address any concerns.

bannner image

Kidney

Caution

Exercise caution before using Bdpalbo 125MG Capsule in case of established kidney disease. Please consult your doctor to address any concerns.

bannner image

Children

Unsafe

Bdpalbo 125MG Capsule is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

Have a query?

FAQs

Bdpalbo 125MG Capsule belongs to the group of anti-cancer drugs used to treat certain types of breast cancer.

Bdpalbo 125MG Capsule works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.

Do not stop taking Bdpalbo 125MG Capsule on your own. You are advised to take Bdpalbo 125MG Capsule for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Bdpalbo 125MG Capsule .

A fibroadenoma is a benign state. Bdpalbo 125MG Capsule is indicated only in case of cancers. Please consult your doctor in case of any concerns.

Bdpalbo 125MG Capsule can reduce fertility in men. Therefore, consider sperm preservation before starting Bdpalbo 125MG Capsule if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Bdpalbo 125MG Capsule .

Bdpalbo 125MG Capsule may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.

Bdpalbo 125MG Capsule is a type of targeted cancer drug. It is a treatment for breast cancer that is oestrogen receptor-positive (ER+) and human epidermal growth factor receptor-negative (HER2 -).

The duration of taking Bdpalbo 125MG Capsule varies from person to person. You take it in cycles (21 days on, 7 days off.), and as long as it's working and manageable, you continue the treatment. Your healthcare team will monitor your progress and adjust the treatment plan as needed.

Most side effects associated with Bdpalbo 125MG Capsule are temporary and can be effectively managed. However, certain side effects may persist or have a lasting impact in some cases. Common reversible side effects include fatigue, nausea, and hair loss, which typically resolve once treatment is stopped. In rare instances, more serious and potentially irreversible side effects may occur, such as permanent hair loss, increased infection risk, or heart problems. Regular monitoring and open communication with your healthcare team are essential to mitigate these risks and address any concerns that may arise during treatment.

Yes, Bdpalbo 125MG Capsule treatment requires blood count monitoring. If neutropenia is mild in the first six cycles, monitor blood counts every 3 months afterwards. This monitoring schedule helps healthcare providers track potential changes in blood counts and adjust treatment accordingly.

Take Bdpalbo 125MG Capsule exactly as your healthcare provider tells you. Swallow the capsule whole with water on an empty stomach at the same time each day. Follow the treatment schedule.

While using Bdpalbo 125MG Capsule , birth control is necessary to prevent pregnancy. Female patients must take a pregnancy test before starting treatment and use birth control during treatment and for at least 3 weeks after the final dose. Male patients, along with their partners, should also use birth control during treatment and for 3 months after the final dose. It's crucial to inform your doctor if you're pregnant, plan to become pregnant, or plan to father a child so they can guide you on the appropriate measures to take.

While women's fertility may not be affected, Bdpalbo 125MG Capsule can decrease fertility in men. Men taking palbociclib may want to talk to their treatment team about sperm preservation before starting treatment.

In some cases, side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or seek emergency medical treatment: fever, chills, or signs of infection; difficulty breathing or shortness of breath; cough with or without mucus; chest pain; dizziness; fast, irregular, or pounding heartbeat; weakness; unusual bleeding or bruising; nosebleeds; or redness, pain, swelling, or blisters on the palms of your hands or soles of your feet, as well as skin blistering, peeling, or redness.

Country of origin

India

Manufacturer/Marketer address

407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Other Info - BDP0011

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:55 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.4449.pdf
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Palbociclib
  3. https://www.cancer.gov/about-cancer/treatment/drugs/palbociclib
  4. https://www.uhs.nhs.uk/Media/SUHTExtranet/Services/Chemotherapy-SOPs/Breastcancer/Fulvestrant-Palbociclib.pdf
  5. https://www.northerncanceralliance.nhs.uk/wp-content/uploads/2018/11/Palbociclib-protocol-CRP13-B033-v1.0.pdf

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