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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Brillo 180 Tablet is used to lower the high cholesterol together with lifestyle changes (diet, weight loss, exercise). It contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

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Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Brillo 180 Tablet

Brillo 180 Tablet is used together with lifestyle changes and certain cholesterol-lowering medicines to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).

Brillo 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

In some cases, Brillo 180 Tablet may cause side effects such as anaemia, gout, and pain in the shoulders, arms or legs. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Brillo 180 Tablet if you are pregnant or breastfeeding. Brillo 180 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Inform the doctor regarding your health condition and medicines you are taking to rule out any possible side effects/interactions.

Uses of Brillo 180 Tablet

Treatment of high cholesterol

Directions for Use

Take Brillo 180 Tablet with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Brillo 180 Tablet belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used in addition to the cholesterol-lowering diet in adult patients with primary hypercholesterolaemia (high cholesterol) or mixed dyslipidaemia (imbalance of lipids), which are conditions that cause a high cholesterol level in the blood. Brillo 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

How Brillo 180 Tablet Works

Brillo 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Brillo 180 Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Gently massage the affected area using your hands or a massager.
  • Light exercises such as walking or climbing stairs may help the muscles return to normal.
  • Apply heat/ice to the affected area.
  • Drink electrolyte-rich fluids.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
  • Eat fatty fish rich in omega-3 fatty acids to reduce inflammation.
  • Add whole grains such as brown rice, quinoa, and whole wheat bread to your diet for a nutritional boost.
  • Add nuts and seeds like almonds, walnuts, chia seeds for anti-inflammatory benefits.
  • Eat dark leafy greens like spinach, kale, collard greens for antioxidants.
  • Include berries like blueberries, strawberries, raspberries for anti-inflammatory properties.
  • Rest and take a break from usual activities.
  • Apply ice for 15-20 minutes, 3 times a day to reduce pain and inflammation.
  • Use compression with a stretchable bandage or wrap to lessen swelling and provide support.
  • Avoid strenuous activities and rest the affected area.
  • Try light stretching with gentle exercises to maintain flexibility.
  • Consider OTC pain medications like ibuprofen or acetaminophen but consult a doctor before taking any medication.

What if I have taken an overdose of Brillo 180 Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Brillo 180 Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Do not take Brillo 180 Tablet if you are allergic to any of its components, if you are pregnant or breastfeeding. Inform the doctor if you have/had gout, severe kidney or liver problems, or tendon problems. Consult the doctor immediately if you become pregnant during treatment with Brillo 180 Tablet . Seek medical attention if you experience symptoms of gout (tender joints, joint redness, severe foot pain, especially in the toe joint, warm joints, and swelling), tendon problems (pain, swelling, tears and inflammation of tendons), or tendon rupture (hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, or are unable to move the affected area or put weight on the affected area).

Drug-Drug Interactions

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Severe

Drug-Drug Interactions

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How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and gatifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Gatifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor immediately. Avoid or limit exercising or using the impacted area. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Brillo 180 Tablet:
Co-administration of Cinoxacin with Brillo 180 Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Brillo 180 Tablet with Cinoxacin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you feel pain or swelling in joints, consult your doctor immediately. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and Deflazacort can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Deflazacort if prescribed by the doctor. However, consult a doctor immediately if you experience pain or swelling in joints. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.
Bempedoic acidGrepafloxacin
Severe
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and Grepafloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Grepafloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and Gemifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Gemifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and Prednisolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Prednisolone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Brillo 180 Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet with Methylprednisolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Methylprednisolone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Brillo 180 Tablet:
Using Simvastatin together with Brillo 180 Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Co-administration of Simvastatin and Brillo 180 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any muscle pain, weakness, fever, dark urine, joint pain or swelling, vomiting, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and Cortisone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Cortisone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of joints, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Brillo 180 Tablet:
Co-administration of Brillo 180 Tablet and enoxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Brillo 180 Tablet can be taken with Enoxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption. 
  • Choose healthy fats and cut down on trans fats.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Brillo 180 Tablet . Please consult a doctor.

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Pregnancy

Unsafe

Brillo 180 Tablet may harm the unborn baby. Do not take Brillo 180 Tablet if you are pregnant, think you may be pregnant or if you are trying to become pregnant. Consult the doctor immediately if you become pregnant during treatment with Brillo 180 Tablet .

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Breast Feeding

Unsafe

It is unknown if Bempedoic acid passes into breast milk. Do not take Brillo 180 Tablet if you are breastfeeding.

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Driving

Safe

Brillo 180 Tablet has little or no influence on your ability to drive.

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Liver

Caution

It is not known if Brillo 180 Tablet is safe and effective in people with liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

It is not known if Brillo 180 Tablet is safe and effective in people with kidney disease, including end-stage kidney disease, who are on dialysis. Please consult the doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Brillo 180 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established.

Have a query?

FAQs

Brillo 180 Tablet is used to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).

Brillo 180 Tablet works by blocking the production of cholesterol in the liver. Thereby, it helps treat high cholesterol.

Do not discontinue Brillo 180 Tablet without consulting your doctor, as it could lead to a rise in cholesterol. To get effective results, continue taking Brillo 180 Tablet for as long as prescribed. Do not hesitate to speak with your doctor if you experience any difficulty while taking Brillo 180 Tablet .

Tendon problems may happen in people taking Brillo 180 Tablet . Consult the doctor if you experience pain, swelling, inflammation and tears of tendons, including Achilles (back of ankle), arm and shoulder. The risk of tendon problems may be increased if you are above 60 years of age, have renal problems, have had tendon problems or are taking antibiotics or corticosteroids.

Brillo 180 Tablet can sometimes cause tiredness. Although it's not a common side effect, some people may feel fatigued while taking it. If you're experiencing this, talk to your doctor. They can help determine if it's related to the medication and recommend what to do.

Brillo 180 Tablet can sometimes affect the liver. While it's generally safe, some people may have slightly elevated liver enzymes. These usually go back to normal on their own. If you notice any signs of liver problems, like yellowing of the skin or dark urine, talk to your doctor right away.

Your doctor may not prescribe Brillo 180 Tablet if you have a history of tendon problems, severe liver problems, or if you're pregnant or breastfeeding. It can also interact with certain other medications. If you have any of these conditions, talk to your doctor before starting Brillo 180 Tablet .

Take it with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.

LDL cholesterol is often called "bad cholesterol" because it can clog your arteries. This can make it harder for blood to reach your heart, increasing your risk of heart problems.

HDL cholesterol is often called "good cholesterol" because it helps clear out bad cholesterol. Higher levels of HDL can be good for your heart health. But it's important to manage both good and bad cholesterol for a healthy heart.

The only way to know whether you have high cholesterol is to get your cholesterol checked. Your health professional can do a simple blood test. This is called a lipid profile.

A healthy level of total cholesterol is below 5mmol/L. HDL (good cholesterol) is above 1.0mmol/L for men or above 1.2mmol/L for women. non-HDL (bad cholesterol) is below 4mmol/L.

High cholesterol can increase your risk of heart problems. It can build up in your arteries and cause problems like heart attacks. If you have symptoms like chest pain, shortness of breath, or fatigue, see a doctor. They can check your cholesterol and recommend treatment.

Lifestyle changes can help Brillo 180 Tablet work better. Eat healthy, exercise regularly, maintain a healthy weight, quit smoking, limit alcohol, and manage stress. These changes can help lower your cholesterol and reduce your risk of heart problems.

No, you should not stop taking Brillo 180 Tablet without consulting your doctor. High cholesterol is a chronic condition, and you may need to continue taking medication to maintain healthy cholesterol levels.

While Brillo 180 Tablet is generally well-tolerated, some people may experience side effects such as muscle pain, joint pain, fatigue, or digestive issues. If you experience any adverse effects, talk to your doctor.

Yes, Brillo 180 Tablet is generally safe for people with diabetes. However, it's important to monitor your blood sugar levels closely while taking this medication.

If you have mild to moderate kidney problems, you may still be able to take Brillo 180 Tablet . However, it's important to discuss this with your doctor, as your dosage may need to be adjusted.

It typically takes 4-8 weeks for Brillo 180 Tablet to start lowering cholesterol levels.

No, Brillo 180 Tablet is not known to cause weight gain.

Yes, Brillo 180 Tablet can be taken with other cholesterol-lowering medications if prescribed by the doctor.

You can lower your cholesterol by eating healthy, exercising, quitting smoking, and managing stress. Sometimes, you might also need medicine.

High cholesterol can be caused by many things, including age, family history, diet, lack of exercise, smoking, being overweight, and having conditions like diabetes or thyroid problems.

It depends on how risky you are of having heart problems. If you have a lot of things that can increase your risk, you might need to check it more often.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - BRI0653

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