CAFIRATE SOLUTION belongs to a group of medicines known as methylxanthines. It is used to treat primary apnoea of premature newborns (interrupted breathing in premature babies). Apnea is a condition where breathing interrupts and causes abnormal heart rate and oxygen saturation alterations. It is a common occurrence, particularly in premature infants.

CAFIRATE SOLUTION contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby CAFIRATE SOLUTION effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

CAFIRATE SOLUTION should be used as prescribed by your doctor. Your doctor will determine the suitable dosage based on your infant's medical conditions. In some cases, CAFIRATE SOLUTION can cause side effects like tachycardia (fast heartbeat), arrhythmia (irregular heartbeat) and hyperglycaemia (increased sugar in blood or serum). These side effects are not prevalent and vary from person to person. Consult your doctor if these symptoms continue or worsen. They may be able to recommend strategies to avoid or minimise certain side effects.

Inform your doctor about the complete medical history of your infant. If you are nursing your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since Caffeine passes into breast milk. This medication should be used with caution in infants with impaired hepatic or renal function. Before fixing the dose, your doctor may assess baseline serum caffeine levels in children born to caffeine-consuming mothers.

CAFIRATE SOLUTION contains 'Caffeine Citrate', which belongs to the central nervous system (CNS) stimulants class. It works in three different ways. Firstly, it is the adenosine receptor antagonist; secondly, it is a phosphodiesterase inhibitor. And thirdly, it is an active intracellular calcium mobiliser. Collectively Caffeine stimulates the respiratory centre, sensitising it to hypercapnia. Thereby CAFIRATE SOLUTION effectively regulates the mean respiratory rate and tidal volume, improves pulmonary blood flow, decreases carbon dioxide sensitivity and enhances diaphragmatic function and breathing pattern.

Inform your doctor about your infant's medical history. If you are breastfeeding and your infant is being treated with this medication, avoid drinking coffee or using any other caffeine-containing products since caffeine passes into breast milk. CAFIRATE SOLUTION should only be used in a neonatal intensive care unit where adequate patient surveillance and monitoring facilities are available. Treatment should begin under the supervision of a neonatologist with experience in neonatal intensive care. This medication should be used with caution in infants with impaired liver or kidney function.