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compositionComposition:CASPOFUNGIN-70MG
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Cagin 70 Injection 1's is used to treat fungal infections. It contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow. As a result, fungal cells get killed, or their growth is minimized.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CASPOFUNGIN-70MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Cagin 70 Injection 1's

Cagin 70 Injection 1's is a specialised medicine used to treat serious fungal infections in the blood, stomach, food pipe, or lungs. It belongs to a group of medicines called antifungals, which work by targeting and stopping the growth of harmful fungi in the body. This treatment is typically prescribed for patients with severe infections or those who have not responded well to other antifungal therapies.

It is given as an injection or infusion into a vein, usually once daily. Because it is given directly into the bloodstream, it does not depend on food intake, meaning it can be administered regardless of when you last ate. To support your recovery, it is helpful to stay well-hydrated and rest while your body fights off the infection.

While taking it, you may experience common side effects like mild fever, headache, or redness at the injection site. However, you must contact your doctor immediately if you experience severe symptoms, such as yellowing of your skin or eyes, dark urine, or signs of a serious allergic reaction.

Do not take this if you have had a severe allergic reaction to this medication in the past. Before starting treatment, tell your doctor if you have any history of liver disease or other underlying health conditions so they can determine if this medicine is safe for you.

This medicine may interact with certain other prescriptions, such as some anti-seizure drugs or medicines that suppress the immune system, which can alter how well the treatment works. You should also consult your healthcare provider if you are pregnant, breastfeeding, or an elderly patient, as special monitoring may be required.

Uses of Cagin 70 Injection 1's

Your doctor may recommend this medicine to help manage the following conditions:

  • Invasive candidiasis: It helps clear severe fungal infections that have entered the bloodstream or deep tissues of the body.
  • Oesophageal candidiasis: It treats fungal infections of the oesophagus, relieving pain and difficulty swallowing.
  • Invasive aspergillosis: This medicine helps treat serious mould infections in the lungs or other organs when other treatments have failed or cannot be tolerated.
  • Suspected fungal infections (empirical approach): It is given as a protective treatment to patients with low white blood cell counts and unexplained fevers who are highly suspected of having a fungal infection.

Key Benefits

When taken consistently as directed, this medicine may provide the following health benefits:

  • Treats serious fungal infections: This medicine helps treat severe fungal infections by stopping the growth of fungi, helping control the infection and supporting recovery.
  • Relieves symptoms: By treating the infection, this medicine helps relieve symptoms such as painful swallowing caused by fungal infections of the food pipe, making it easier to eat and drink comfortably.
  • Works quickly through a vein: As this medicine is given directly into a vein, it reaches the bloodstream immediately, making it a suitable option for patients who are seriously ill or unable to take medicines by mouth.
Side effects of Cagin 70 Injection
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Cagin 70 Injection 1's will be administered in the hospital setting by a trained healthcare professional.
  • Do not self-administer.

How Cagin 70 Injection 1's Works

This medicine contains Cagin 70 Injection 1's as an active ingredient. It works by blocking beta-(1,3)-D-glucan synthase, an enzyme that fungi need to produce beta-(1,3)-D-glucan, an important part of their protective cell wall. Without enough beta-(1,3)-D-glucan, the fungal cell wall becomes weak and unstable, preventing the fungi from growing and allowing the fungal cells to die. Because human cells do not have fungal cell walls or use beta-(1,3)-D-glucan, this medicine targets the infection without harming your body's healthy cells.
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Alcohol

Caution

Avoiding alcohol is recommended to rule out any possibility of side effects.

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Pregnancy

Caution

Cagin 70 Injection 1's is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Caution

If you are breastfeeding, please inform your doctor. It is not known if Cagin 70 Injection 1's passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Cagin 70 Injection 1's.

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Driving

Caution

Cagin 70 Injection 1's may cause dizziness; therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

Inform your doctor before receiving the Cagin 70 Injection 1's if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before receiving the Cagin 70 Injection 1's if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Please consult your doctor. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Heart

Caution

Inform your doctor before receiving the Cagin 70 Injection 1's if you have a heart disorder. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Safe if prescribed

Cagin 70 Injection 1's is generally safe for elderly patients. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Cagin 70 Injection 1's

This medicine is prepared and given under strict medical supervision, making an accidental overdose highly unlikely. If you suspect you have received too much or experience unusual symptoms, inform your healthcare provider immediately.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day to support your kidneys and help your body process the medication efficiently.
  • Eat soft foods: If you are being treated for a throat or food pipe infection, stick to soft, lukewarm, or cool foods that are easy to swallow. Avoid spicy, highly acidic, or very hot foods that can irritate your throat.
  • Prioritise rest: Fighting a serious fungal infection takes a toll on your body. Get plenty of sleep and avoid strenuous physical activity until your doctor says it is safe to resume.
  • Maintain gentle oral care: Use a soft-bristled toothbrush and rinse your mouth gently with water after meals to keep your oral cavity clean and comfortable during recovery.
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How Soon It Starts Working

The time required for Cagin 70 Injection 1's to start to work: The effect of Cagin 70 Injection 1's starts within a few hours of administration. The time for which the effects of Cagin 70 Injection 1's last: The duration of Cagin 70 Injection 1's effect is unknown.

What if you forget to take Cagin 70 Injection 1's

Because this medicine is given by a healthcare professional, missing a dose is unlikely. However, if you miss a scheduled appointment for your infusion, contact your doctor or clinic immediately to reschedule. Keeping a consistent schedule is important to prevent the infection from returning.

Storage

• Unopened vials of the dry powder of medicine must be stored in a refrigerator between 2°C and 8°C (36°F and 46°F).

Drug Warnings

  • Inspect the solution: Before the medicine is injected, ensure the liquid is clear and colourless to pale yellow. Do not use if you notice any floating particles or cloudiness.
  • Monitor your liver: Your doctor will likely schedule regular blood tests to check your liver enzymes while you are on this medicine to ensure your liver remains healthy.
  • Watch for infusion reactions: Inform your nurse immediately if you feel warm, dizzy, itchy, or start sweating during your infusion, as the rate of delivery may need to be adjusted.
  • Do not stop early: Complete your full recommended course of therapy even if you start feeling completely recovered. Stopping too early can allow the fungal infection to return.

Drug-Drug Interactions

verifiedApollotooltip
  • Cyclosporine: Using this immunosuppressant with this medicine may increase the risk of liver damage. Your doctor may need to monitor your liver enzymes closely.
  • Tacrolimus: This medicine can lower the levels of tacrolimus in your bloodstream. Your doctor may monitor your blood levels and adjust your tacrolimus dose if necessary.
  • Enzyme-inducing medicines: Medicines such as rifampin, phenytoin, carbamazepine, or dexamethasone may lower the amount of this medicine in your blood, making it less effective. Your doctor may adjust your treatment or dose if needed. 
CaspofunginFosphenytoin
Severe

Drug-Drug Interactions

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CaspofunginFosphenytoin
Severe
How does the drug interact with Cagin 70 Injection:
Coadministration of Cagin 70 Injection and Fosphenytoin can reduce the levels of Cagin 70 Injection in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Cagin 70 Injection and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Cagin 70 Injection:
Taking Rifampicin in combination with Cagin 70 Injection may make Cagin 70 Injection less effective.

How to manage the interaction:
There may be a possibility of interaction between Cagin 70 Injection and Rifampicin, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Cagin 70 Injection:
Taking carbamazepine and Cagin 70 Injection together may result in decreasing the effects of Cagin 70 Injection.

How to manage the interaction:
Although taking carbamazepine and Cagin 70 Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Cagin 70 Injection:
Leflunomide can cause liver problems, and combining it with other drugs, such as binimetinib, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Cagin 70 Injection, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include liver problems, fever, rash, itching, loss of appetite, dark urine, stomach pain, unusual bleeding or bruising, feeling tired, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cagin 70 Injection:
Coadministration of ketoconazole with Cagin 70 Injection may raise the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Cagin 70 Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Cagin 70 Injection:
Co-administration of Dexamethasone with Cagin 70 Injection may cause Cagin 70 Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Cagin 70 Injection and Dexamethasone, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cagin 70 Injection:
Using nevirapine together with Cagin 70 Injection may cause Cagin 70 Injection to be less effective.

How to manage the interaction:
Although there is a possible interaction between Cagin 70 Injection and Nevirapine, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cagin 70 Injection:
Coadministration of Phenytoin and Cagin 70 Injection may decrease the blood levels of Cagin 70 Injection, which may make Cagin 70 Injection less effective.

How to manage the interaction:
Although taking Phenytoin and Cagin 70 Injection together can result in an interaction, it can be taken if your doctor has prescribed it. If your infection gets worse or if your symptoms don't go away, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Cagin 70 Injection:
Taking Cagin 70 Injection and Efavirenz together reduces the levels and effectiveness of Cagin 70 Injection.

How to manage the interaction:
Although taking Cagin 70 Injection and Efavirenz together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Cagin 70 Injection 1's when used as directed.     
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIFUNGALS]

FAQs

Cagin 70 Injection 1's is used to treat Fungal infections.
Cagin 70 Injection 1's contains Caspofungin, which inhibits the formation of a fungal cell wall component required for the fungus to continue living and growing. When fungal cells are exposed to Caspofungin, their cell walls become partial or faulty, making them fragile and unable to grow.
Cagin 70 Injection 1's is not suitable for patients with known hypersensitivity to any components present in Cagin 70 Injection 1's.
Cagin 70 Injection 1's is unlikely to interfere with your contraception, including the combination pill or emergency contraception. For further information, seek medical advice from your healthcare professional.
Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, avoiding close direct contact until the infection is clear and avoiding sharing things with the infected person is recommended, as it can also spread the infection.
No, you can continue to eat and drink normally while taking Cagin 70 Injection 1's unless instructed by the doctor.
No, Cagin 70 Injection 1's is not an antibiotic. It belongs to the class of medicines called antifungals.
Cagin 70 Injection 1's is administered as a slow intravenous injection, usually once a day, by a qualified healthcare professional. The injection is given over about one hour. The dosage and treatment duration will be determined by your doctor based on your specific condition. Do not self-administer.
Cagin 70 Injection 1's is effective when used as per the dosage and duration recommended by a doctor. Do not self-medicate.
Cagin 70 Injection 1's causes side effects such as injection site reactions, headache, dizziness, chills, nausea, vomiting, diarrhoea, stomach pain tremor, high blood pressure, swelling of hands, ankles, or feet and difficulty sleeping. Please, consult a doctor if these persist for longer durations.
Yes, in some cases, you may receive your daily infusions at home with the assistance of a trained home health nurse once your doctor determines it is safe. Talk to your doctor to see if this is an option for you.
This medicine is generally not recommended during pregnancy unless the benefits clearly outweigh the risks to the unborn baby. Talk to your doctor or pharmacist if you are pregnant or planning to become pregnant.
While there is no direct chemical interaction between alcohol and this medicine, alcohol can place additional stress on your liver, which is already processing the medication. Talk to your doctor for personalised advice.
Alert your healthcare provider immediately, as a rash could be a sign of an allergic or infusion-related reaction that requires medical attention or an adjustment to the infusion speed. Talk to your doctor.
No, it is specifically an antifungal medicine designed to treat infections caused by fungi and yeasts; it is not effective against viruses or bacteria. Talk to your doctor or pharmacist.
Yes, your doctor will likely perform routine blood tests to monitor your liver enzymes and check your blood potassium levels to ensure you are tolerating the medication safely. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Fc/B-1 (Extn.), Mohan Co-Operative Industrial Estate Mathura Road, New Delhi - 110 044.
Other Info - CAG0002
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