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  1. Home
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  3. Chilkul-ED Capsule 10's

Prescription drug
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Chilkul-ED Capsule 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Chilkul-ED Capsule 10's is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers. It contains Esomeprazole and Domperidone, which blocks acid production and increases the movements and contractions of stomach muscles. Thus, helps in treating acidity-related problems. It may cause common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DOMPERIDONE-30MG + ESOMEPRAZOLE-40MG

Manufacturer/Marketer :

Aptus Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Chilkul-ED Capsule 10's

Chilkul-ED Capsule 10's belongs to the class of drugs known as Proton pump inhibitors, which reduce the amount of acid your stomach produces. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Chilkul-ED Capsule 10's is a combination of Esomeprazole and Domperidone that helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus preventing the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Chilkul-ED Capsule 10's will get these side effects. In some cases, you may experience certain common side effects, such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve over time. However, if you experience these side effects persistently, talk to your doctor.

Take Chilkul-ED Capsule 10's as advised. Your physician will decide the dosage based on your medical condition. You should take Chilkul-ED Capsule 10's 30 minutes before food. It is recommended not to exceed the recommended dose of Chilkul-ED Capsule 10's. Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Chilkul-ED Capsule 10's. Consult your doctor before taking Chilkul-ED Capsule 10's if you are pregnant or breastfeeding. Chilkul-ED Capsule 10's may cause dizziness, so drive only if you are alert. Chilkul-ED Capsule 10's should not be given to children as safety has not been established. Avoid consuming alcohol and Chilkul-ED Capsule 10's as it could lead to increased drowsiness and elevate stomach acid production.

Uses of Chilkul-ED Capsule 10's

Chilkul-ED Capsule 10's is used to treat Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and Stomach ulcers. The detailed uses of Chilkul-ED Capsule 10's are as follows:

  • Gastric reflux disease (GERD): By lowering stomach acid, Chilkul-ED Capsule 10's helps control GERD symptoms such as acid reflux, regurgitation, and heartburn.
  • Ulcer Treatment: Chilkul-ED Capsule 10's promotes healing and inhibits recurrence by treating duodenal and stomach ulcers.
  • Zollinger-Ellison Syndrome: By lowering the production of excessive stomach acid, Chilkul-ED Capsule 10's helps to control symptoms and avoid problems.
  • Management of Erosive Esophagitis: Chilkul-ED Capsule 10's heals oesophagal damage brought on by acid reflux by treating erosive esophagitis.
  • Relief from nausea and vomiting: Chilkul-ED Capsule 10's offers immediate relief by blocking certain substances in the body that cause nausea and vomiting.

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Directions for Use

  • Take Chilkul-ED Capsule 10's an hour before your meal, ideally in the morning or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Chilkul-ED Capsule 10's is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.
  • Chilkul-ED Capsule 10's works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Chilkul-ED Capsule 10's helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How Chilkul-ED Capsule 10's Works

Chilkul-ED Capsule 10's is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Chilkul-ED Capsule 10's helps in treating acidity-related problems.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Chilkul-ED Capsule
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

What if I have taken an overdose of Chilkul-ED Capsule 10's

Do not take more than the prescribed dose of Chilkul-ED Capsule 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

  • Avoid taking Chilkul-ED Capsule 10's if you are allergic to Chilkul-ED Capsule 10's or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1.
  • Inform your doctor before taking Chilkul-ED Capsule 10's if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection.
  • Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Chilkul-ED Capsule 10's.
  • On long-term treatment, Chilkul-ED Capsule 10's may cause low magnesium levels, vitamin B12 levels, and might increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Chilkul-ED Capsule 10's may cause dizziness, so drive only if you are alert.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).
  • Chilkul-ED Capsule 10's should not be given to children as safety has not been established.
  • Avoid consuming alcohol along with Chilkul-ED Capsule 10's as it could lead to increased drowsiness and can elevate the production of stomach acid.
  • A prolonged intake of Chilkul-ED Capsule 10's is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor. 

Drug-Drug Interactions

verifiedApollotooltip
EsomeprazoleRilpivirine
Critical
DomperidoneHalofantrine
Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Chilkul-ED Capsule:
Chilkul-ED Capsule may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Chilkul-ED Capsule with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
DomperidoneHalofantrine
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Halofantrine can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Chilkul-ED Capsule and Halofantrine together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Chilkul-ED Capsule and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMethadone
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Methadone can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Chilkul-ED Capsule and Methadone together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with Chilkul-ED Capsule:
Combining Mizolastine with Chilkul-ED Capsule can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking Chilkul-ED Capsule and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Chilkul-ED Capsule and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Chilkul-ED Capsule and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Nefazodone can increase the blood levels of Chilkul-ED Capsule.

How to manage the interaction:
There may be a possibility of interaction between Chilkul-ED Capsule and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with Chilkul-ED Capsule:
Coadministration of Chilkul-ED Capsule with Ritonavir can increase the blood levels of Chilkul-ED Capsule.

How to manage the interaction:
There may be a possibility of interaction between Chilkul-ED Capsule and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with Chilkul-ED Capsule:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Chilkul-ED Capsule and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Chilkul-ED Capsule 10's. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Consult your doctor

Consult your doctor before taking Chilkul-ED Capsule 10's if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Chilkul-ED Capsule 10's; your doctor will decide whether Chilkul-ED Capsule 10's can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Chilkul-ED Capsule 10's may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Chilkul-ED Capsule 10's if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Chilkul-ED Capsule 10's if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Chilkul-ED Capsule 10's should not be given to children as safety and effectiveness were not established.

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Heart

Unsafe

This medicine is not recommended in cardiac patients due to its adverse effects. However, if prescribed extreme caution should be exercised.

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Geriatrics

Caution

Chilkul-ED Capsule 10's can be given in elderly patients with caution due to the serious adverse effects.

FAQs

Chilkul-ED Capsule 10's is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, and stomach ulcers.

Chilkul-ED Capsule 10's contains Esomeprazole and Domperidone. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of stomach muscles. Together, Chilkul-ED Capsule 10's helps in treating acidity.

Diarrhoea might be a side-effect of Chilkul-ED Capsule 10's. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in your stools.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Dry mouth could be a side-effect of Chilkul-ED Capsule 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Chilkul-ED Capsule 10's contains domperidone which helps in treating nausea and vomiting by increasing the movements and contractions of stomach muscles.

Do not take Chilkul-ED Capsule 10's for longer durations unless prescribed by the doctor. Consult your doctor if your condition does not improve even after taking Chilkul-ED Capsule 10's for 14days.

Chilkul-ED Capsule 10's should not be taken along with HIV medicines such as atazanavir, ritonavir, nelfinavir, and saquinavir as Chilkul-ED Capsule 10's might affect their absorption. Consult your doctor before taking Chilkul-ED Capsule 10's with other medicines to avoid unpleasant side-effects.

On long-term treatment, Chilkul-ED Capsule 10's might increase the risk of bone fracture in the spine, wrist or hip. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, as they can increase the risk of bone fractures.

Chilkul-ED Capsule 10's belongs to a group of gastrointestinal agents. It contains Esomeprazole and Domperidone, which help treat acidity-related conditions.

Yes, it is safe to use Chilkul-ED Capsule 10's if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Take Chilkul-ED Capsule 10's on an empty stomach, 1 hour before meals.

Chilkul-ED Capsule 10's may cause abnormal heartbeat. Consult the doctor if you have symptoms of irregular heartbeat like fainting, dizziness, and palpitations.

Chilkul-ED Capsule 10's should not be used if you are allergic to any of its components or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, or heart problems.

Dry mouth could be a side effect of Chilkul-ED Capsule 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

Chilkul-ED Capsule 10's may cause dizziness. Do not drive or operate machinery unless you are alert.

Yes, inform the doctor if you are pregnant or breastfeeding before taking Chilkul-ED Capsule 10's. The doctor will prescribe Chilkul-ED Capsule 10's if the benefits outweigh the risks.

If you miss a dose of Chilkul-ED Capsule 10's take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.

Avoid consumption of alcohol while taking Chilkul-ED Capsule 10's. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Store Chilkul-ED Capsule 10's at room temperature (not exceeding 30°C) protected from light and moisture. Keep out of reach of children.

Side effects of Chilkul-ED Capsule 10's include dry mouth, stomach pain, diarrhoea, headache, and flatulence. Talk to your doctor if you experience these side effects persistently.

Country of origin

India

Manufacturer/Marketer address

Aptus Pharma Pvt Ltd, Aptus Pharma Platno-37, Rukda Nagar, Ahmedabad-361001, Gujarat, India
Other Info - CHI0363

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Dec 3, 2025 | 7:32 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.ciplamed.com/content/esomac-d-capsules
  2. https://vibcare.co.in/esomeprazole-domperidone-sr/
  3. https://www.dmpharma.co.in/Esomeprazoledomperidone.html
  4. https://wellonapharma.com/product/finished/esomeprazole-and-domperidone-capsules

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