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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Cifran-D Eye/Ear Drops is a combination medicine used to treat eye and ear infections caused by bacteria. It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection causing bacteria. This medicine is not effective for treating viral infections. Sometimes, you may experience certain common side effects, such as eye discomfort, irritation, eye pain, and stinging sensation
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Manufacturer/Marketer :

Ranbaxy Laboratories Ltd

Consume Type :

EYE/EAR

Return Policy :

Not Returnable

Expires on or after :

About Cifran-D Eye/Ear Drops

Cifran-D Eye/Ear Drops is a combination of antibiotic and steroid medication used to treat bacterial eye and ear infections. An ear infection occurs when bacteria invade the middle or outer ear, causing pain and inflammation. Bacterial eye infection occurs when pathogenic bacteria enter any eye portion, including the eyeball, conjunctiva, and cornea.

Cifran-D Eye/Ear Drops contains ciprofloxacin and dexamethasone. Ciprofloxacin has bactericidal activity and works by suppressing the enzyme DNA gyrase, which is essential for bacterial DNA synthesis. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation by inhibiting the chemicals such as prostaglandins that cause inflammation. As a result, Cifran-D Eye/Ear Drops treats bacterial eye/ear infections.

You are advised to use Cifran-D Eye/Ear Drops for as long as your doctor has prescribed it. Sometimes, you may experience certain common side effects, such as discomfort, irritation, stinging sensation, and dysgeusia (taste disorder). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Cifran-D Eye/Ear Drops if you are allergic to any of its components. Talk to your doctor if the irritation persists despite using Cifran-D Eye/Ear Drops for a week or if it worsens. Consult your doctor before using Cifran-D Eye/Ear Drops if you are pregnant or breastfeeding. Please do not touch the tip of the dropper to the eye/ear or surrounding areas as it may contaminate the contents. Cifran-D Eye/Ear Drops should be used in children only if prescribed by the doctor.

Uses of Cifran-D Eye/Ear Drops

Treatment of Bacterial eye/ear infections

Directions for Use

• Follow your doctor’s instructions on the dosage and duration of treatment. • For eye use: Wash your hands, tilt your head back, pull down your lower eyelid, and instil the prescribed number of drops into the eye.• For ear use: Lie on your side or tilt your head so the ear faces up, pull the ear upward and outward, and instil the prescribed number of drops into the ear.• To avoid contamination, do not touch the tip of the container.

Medicinal Benefits

Cifran-D Eye/Ear Drops contains ciprofloxacin and dexamethasone. Ciprofloxacin is a fluoroquinolone antibiotic that kills bacteria by preventing their growth. Dexamethasone is a steroid that reduces inflammation and infection-related symptoms such as redness and discomfort. It acts by inhibiting the chemicals that cause inflammation, such as prostaglandins. As a result, Cifran-D Eye/Ear Drops aids in treating eye/ear infections.

How Cifran-D Eye/Ear Drops Works

Cifran-D Eye/Ear Drops contains ciprofloxacin and dexamethasone. Ciprofloxacin has bactericidal activity and works by suppressing the enzyme DNA gyrase, which is essential for bacterial DNA synthesis. Dexamethasone is a steroid that reduces inflammation and symptoms associated with infection, such as redness and irritation by inhibiting the chemicals such as prostaglandins that cause inflammation. As a result, Cifran-D Eye/Ear Drops treats bacterial eye/ear infections.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Cifran-D Eye/Ear Drops

Use Cifran-D Eye/Ear Drops as prescribed. Overdose may cause rash. hives. swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs. Seek immediate medical help if you experience any of these symptoms.

Drug Warnings

Do not use Cifran-D Eye/Ear Drops if you are allergic to any of its components. Before using Cifran-D Eye/Ear Drops, inform your doctor if you have vision problems, severe eye pain, glaucoma (high blood pressure), eye damage, eye surgery, hearing problems (cytotoxicity), a perforated eardrum, chronic otitis media, or viral ear infections (herpes simplex otitis externa and herpes zoster otitis external). Notify the doctor if you are pregnant, planning to become pregnant, or are breastfeeding. Contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

Drug-Drug Interactions

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CiprofloxacinMesoridazine
Critical

Drug-Drug Interactions

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How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Coadministration of Cifran-D Eye/Ear Drops 10 ml and Tizanidine together can increase the risk of side effects.

How to manage the interaction:
Using Cifran-D Eye/Ear Drops 10 ml and Tizanidine together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
CiprofloxacinMesoridazine
Critical
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Using Cifran-D Eye/Ear Drops 10 ml with Mesoridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Coadministration of Cifran-D Eye/Ear Drops 10 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
CiprofloxacinProcainamide
Critical
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Using Cifran-D Eye/Ear Drops 10 ml with Procainamide can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Procainamide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Taking Amiodarone and Cifran-D Eye/Ear Drops 10 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone with Cifran-D Eye/Ear Drops 10 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Combining Cifran-D Eye/Ear Drops 10 ml with Thioridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Using Cifran-D Eye/Ear Drops 10 ml with Cisapride can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Cisapride is not recommended, it can be take if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Coadministration of sotalol together with Cifran-D Eye/Ear Drops 10 ml can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Sotalol with Cifran-D Eye/Ear Drops 10 ml is generally avoided as it can result in an interaction, it can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty. Do not discontinue any medications without consulting a doctor.
CiprofloxacinHalofantrine
Critical
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
Using Cifran-D Eye/Ear Drops 10 ml with Halofantrine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Cifran-D Eye/Ear Drops 10 ml:
When Cifran-D Eye/Ear Drops 10 ml is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Cifran-D Eye/Ear Drops 10 ml with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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CIPROFLOXACIN-0.3%W/V+DEXAMETHASONE-0.1%W/VCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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CIPROFLOXACIN-0.3%W/V+DEXAMETHASONE-0.1%W/VCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Using caffeine together with ciprofloxacin may increase the effects of caffeine. Taking dairy products such as milk, yogurt, or calcium-fortified foods can make the medication less effective. Avoid taking caffeine with ciprofloxacin, as it causes effects. Contact your doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. Avoid taking milk, yogurt, or calcium-fortified foods. You could interrupt the feeding for 1 hour before and 2 hours after the ciprofloxacin dose. Do not stop using any medications without talking to your doctor.

Diet & Lifestyle Advise

Ear infection:

  • Consult an ENT on a regular basis to ensure early detection of any ear problems.
  • Avoid consuming foods that you are allergic to as it can cause the body to produce excess mucus, resulting in ear inflammation.
  • Avoid getting shampoo, soap, or water into your ears as this can cause itching.
  • Poking or scratching the ear can cause damage to the ear canal, resulting in inflammation. 
  • Using cotton swabs, bobby pins, or other objects to remove earwax may push wax deeper into the ear, causing ear damage.
  • Never put cold water in your ear, and avoid spraying liquids into your ear with force.

Eye infection:

  • Get at least six to eight hours of sleep each night to renew your eyes.
  • Wash your eyes with clean water. If you have had eye surgery, wait at least two weeks before washing your eyes.
  • Take care of your health, eat a balanced diet, exercise regularly, and rest well.
  • Hydrate well-drink lots of water.
  • Wash your hands regularly, and avoid touching your eyes with dirty hands.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS AND STEROID
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Alcohol

Caution

No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

If you are planning to become pregnant or are already pregnant, please consult your doctor before using Cifran-D Eye/Ear Drops.

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Breast Feeding

Caution

If you are a nursing mother, please notify your doctor before beginning Cifran-D Eye/Ear Drops.

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Driving

Caution

Cifran-D Eye/Ear Drops may cause blurred vision temporarily after using the drops in the eye. Before driving or operating any machinery, wait until your vision is clear.

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Liver

Caution

Limited information is available about the usage of Cifran-D Eye/Ear Drops in patients with liver disease. Please consult your physician.

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Kidney

Caution

Limited information is available about the usage of Cifran-D Eye/Ear Drops in patients with kidney disease. Please consult your physician.

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Children

Caution

Cifran-D Eye/Ear Drops should be used in children above one year only if prescribed by the doctor.

Have a query?

FAQs

Cifran-D Eye/Ear Drops is a combination of antibiotic and steroid medication used to treat bacterial eye and ear infections. An ear infection occurs when bacteria invade the middle or outer ear, causing pain and inflammation.

Cifran-D Eye/Ear Drops contains ciprofloxacin and dexamethasone. Ciprofloxacin kills the bacteria by inhibiting their growth. Dexamethasone works by inhibiting the chemicals such as prostaglandins that cause inflammation. Thereby, Cifran-D Eye/Ear Drops helps treat ear/eye infections.

Please do not stop using Cifran-D Eye/Ear Drops until the course advised by the doctor has been completed. If you discontinue Cifran-D Eye/Ear Drops suddenly, your symptoms may reappear.

Wearing contact lenses during treatment is not recommended unless advised by the doctor. Remove contact lens before instilling the drops into the eye and wait at least 15 minutes before reinserting them.

You are not recommended to use Cifran-D Eye/Ear Drops for more than the prescribed duration. Talk to your doctor if the irritation persists despite using Cifran-D Eye/Ear Drops for a week or if it worsens.

Cifran-D Eye/Ear Drops starts working within a few hours of use. However, it may take a few days to show its complete effectiveness.

Cifran-D Eye/Ear Drops is a combination of an antibiotic and a steroid used to treat bacterial infections in the eyes and ears. It helps to kill the bacteria that cause infection and reduces swelling, redness, and pain.

Consult the doctor before using Cifran-D Eye/Ear Drops if you are pregnant or breastfeeding. The doctor will prescribe the medication only if the benefits outweigh the risks.

Cifran-D Eye/Ear Drops should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

If you miss a dose of Cifran-D Eye/Ear Drops, use it as soon as possible. However, if it is almost time for the next dose, skip the missed one and use the scheduled dose. Do not double the dose.

The side effects of Cifran-D Eye/Ear Drops include stinging sensation, dysgeusia (taste disorder), irritation, local burning sensation and discomfort. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

52, Industrial Area Phase-1, Chandigarh.
Other Info - CIF0109

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