apollo
logo
0
Introducing Our Latest Arrival!
Cleft 10 Tablet 10's

Cleft 10 Tablet 10's

Prescription drug
 Trailing icon

Composition

LEFLUNOMIDE-10MG

Manufacturer/Marketer

Sun Pharmaceutical Industries Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

About Cleft 10 Tablet 10's

Cleft 10 Tablet 10's belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales). 

Cleft 10 Tablet 10's contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling. 

Take Cleft 10 Tablet 10's at the same time every day as prescribed by your doctor. In some cases, Cleft 10 Tablet 10's may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Cleft 10 Tablet 10's if you are pregnant or planning for pregnancy as Cleft 10 Tablet 10's may cause serious congenital disabilities. Cleft 10 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. Cleft 10 Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol along with Cleft 10 Tablet 10's as it could lead to increased dizziness and liver damage. Cleft 10 Tablet 10's may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Uses of Cleft 10 Tablet 10's

Treatment of Rheumatoid arthritis, Psoriatic arthritis

Medicinal Benefits

Cleft 10 Tablet 10's belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Cleft 10 Tablet 10's is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.

Directions for Use

Take Cleft 10 Tablet 10's with or without food. Swallow Cleft 10 Tablet 10's as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cleft 10 Tablet 10's

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Indigestion
  • Rash
  • Hair loss

Drug Warnings

Do not take Cleft 10 Tablet 10's if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Cleft 10 Tablet 10's is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Cleft 10 Tablet 10's if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Cleft 10 Tablet 10's may cause dizziness, so drive with caution. Cleft 10 Tablet 10's may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug Interactions

Drug-Drug Interactions: Cleft 10 Tablet 10's may interact with pain killers (ibuprofen, naproxen, acetaminophen, aspirin), anti-depressant (duloxetine), corticosteroids (prednisone), drugs used to treat arthritis (celecoxib, azathioprine, etanercept, adalimumab, meloxicam, methotrexate, abatacept, infliximab), and anti-malarial (hydroxychloroquine). 

Drug-Food Interactions: Avoid consuming alcohol along with Cleft 10 Tablet 10's as it could lead to liver damage.

Drug-Disease Interactions: Inform your doctor if you have low immunity, pneumonia, tuberculosis (TB), hypertension (high blood pressure), lung toxicity, peripheral neuropathy (nerve damage), liver and kidney dysfunction.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • ACETAMINOPHEN
  • ASPIRIN
  • DULOXETINE
  • PREDNISONE
  • CELECOXIB
  • AZATHIOPRINE
  • MELOXICAM
  • METHOTREXATE
  • ETANERCEPT
  • ADALIMUMAB
  • ABATACEPT
  • INFLIXIMAB
  • HYDROXYCHLOROQUINE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Special Advise

Regular blood tests to monitor your liver function after starting Cleft 10 Tablet 10's, and for every 6-8 weeks are advised.

Disease/Condition Glossary

Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness. 

Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.

bannner image

Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Cleft 10 Tablet 10's. Alcohol intake, along with Cleft 10 Tablet 10's, may cause liver disease.

bannner image

Pregnancy

Unsafe

It is not recommended to take Cleft 10 Tablet 10's while you are pregnant. Cleft 10 Tablet 10's may cause serious birth defects.

bannner image

Breast Feeding

Unsafe

It is not recommended to take Cleft 10 Tablet 10's while you are breastfeeding. Cleft 10 Tablet 10's passes into breast milk.

bannner image

Driving

Caution

Cleft 10 Tablet 10's may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Please consult your doctor if you have liver impairment before taking Cleft 10 Tablet 10's.

bannner image

Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Cleft 10 Tablet 10's.

bannner image

Children

Unsafe

Cleft 10 Tablet 10's is not approved for children under the age of 18 years.

Country of origin

India

Manufacturer/Marketer address

Suite No. 704, 706, 708, Suneja Tower II Distt. center Janak Puri, New Delhi-110058, Delhi, India
Other Info -

FAQs

Cleft 10 Tablet 10's is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).
Cleft 10 Tablet 10's may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Cleft 10 Tablet 10's. Take Cleft 10 Tablet 10's for as long as your doctor has prescribed to treat your condition effectually.
Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Add to Cart