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More about the Product

Composition :

AMMONIUM CHLORIDE-138MG+DIPHENHYDRAMINE HYDROCHLORIDE-14.08MG+SODIUM CITRATE-57.03MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About COFRYL Cough Syrup

COFRYL Cough Syrup is an oral liquid medication used to treat wet coughs, chest congestion, and common allergy symptoms. It helps loosen stubborn phlegm, soothe throat irritation, and relieve symptoms such as a runny nose, sneezing, and watery eyes caused by colds or respiratory allergies. This medicine supports easier mucus clearance and helps manage seasonal allergy discomfort, but it is not a true nasal decongestant.

To get the best results, you should take this medicine consistently at the times recommended by your doctor. You can take COFRYL Cough Syrup with or without food, though taking it with a glass of water can help further soothe your throat. Incorporating simple lifestyle habits, like drinking plenty of warm fluids and using a room humidifier, can also help clear your airways faster.

While taking COFRYL Cough Syrup , you may notice some mild side effects like drowsiness, dizziness, or a dry mouth. These symptoms are common and usually go away on their own, but you should contact your doctor immediately if you experience severe allergic reactions, trouble breathing, or a rapid heart rate.

Before you start taking this medicine, discuss your medical history with your doctor, especially if you have chronic respiratory conditions, narrow-angle glaucoma, or prostate issues. Do not take this if you are allergic to any of its ingredients, have severe liver damage, or have taken certain depression medications (MAOIs) in the last 14 days.

Avoid drinking alcohol or taking sleeping pills while using COFRYL Cough Syrup , because combining these substances can cause severe drowsiness and slow down your reaction times. Pregnant women, breastfeeding mothers, and elderly patients should consult their doctor before using this medicine to ensure it is safe for them.

Uses of COFRYL Cough Syrup

Your doctor may prescribe COFRYL Cough Syrup to treat several symptoms related to colds, allergies, and respiratory issues. It is commonly used for:

  • Cough with mucus: It helps thin and loosen sticky phlegm in the airways, making it much easier to cough up and clear your chest.
  • Allergy symptoms: It provides relief from runny nose, sneezing, watery eyes, and itchy throat caused by seasonal allergies or environmental triggers.
  • Chest congestion and allergy symptoms: It helps loosen mucus in the chest while relieving allergy-related symptoms such as a runny nose, sneezing, and watery eyes. It does not directly reduce swelling inside the nasal passages like a decongestant.

Key Benefits

This medicine helps relieve cough, loosen mucus, and reduce allergy symptoms for more comfortable breathing. Its benefits include:

  • Helps relieve cough and reduce the frequency of coughing fits.
  • Helps loosen and clear thick mucus from the airways.
  • Relieves allergy symptoms such as a runny nose, sneezing, and throat irritation.
  • Helps reduce chest congestion and makes breathing more comfortable.
  • Promotes better sleep by calming cough, especially at night.
  • Supports a quicker and more comfortable recovery from cough and cold symptoms.
Side effects of COFRYL Cough Syrup 100 ml
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • If taking a prescription drug causes euphoria as a side effect. Discuss with your physician. Medication changes or dosage adjustments can be required.
  • Activities that benefit stabilize mood include breathing techniques, meditation, and moderate yoga.
  • Normal sleep habits, as rest is necessary for emotional balance.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • COFRYL Cough Syrup can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Avoid using regular household spoons, as they may not measure the dose correctly.

How COFRYL Cough Syrup Works

COFRYL Cough Syrup contains Diphenhydramine, Ammonium chloride, and Sodium citrate. Diphenhydramine: It is an antihistamine that blocks histamine, a natural substance responsible for allergy symptoms such as a runny nose, sneezing, watery eyes, and itching. It also helps dry excessive secretions, which may reduce throat irritation and provide additional relief from coughing associated with allergies. Ammonium chloride: It is a traditional expectorant that helps loosen and clear mucus from the airways through indirect mechanisms. Drinking plenty of fluids while taking this medicine further helps thin mucus and makes it easier to cough up. Sodium citrate: It is an alkalinizing buffer that helps increase the pH of mucus secretions, making them less thick and easier to clear from the airways. This supports the natural removal of mucus during coughing.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking COFRYL Cough Syrup as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Avoid taking COFRYL Cough Syrup if you are breastfeeding. Consult your doctor if you have any concerns.

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Driving

Caution

COFRYL Cough Syrup may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

COFRYL Cough Syrup should be given to children only if prescribed by the doctor.

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Heart

Caution

COFRYL Cough Syrup should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using COFRYL Cough Syrup .

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Geriatrics

Caution

COFRYL Cough Syrup should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of COFRYL Cough Syrup

If you suspect an overdose, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose may include extreme drowsiness, severe dizziness, dry mouth, dilated pupils, fever, or excitability (especially in children).

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of warm water, decaffeinated tea, or clear broths. Increased fluid intake works naturally with the expectorant in COFRYL Cough Syrup to thin out mucus.
  • Use a cool-mist humidifier: Adding moisture to the air in your home or bedroom keeps your nasal passages and throat from drying out, which reduces coughing.
  • Avoid tobacco smoke: Stay away from active smoking and secondhand smoke. Smoke irritates your airways and can make mucus buildup and coughing significantly worse.
  • Inhale steam: Taking a warm shower or inhaling steam from a bowl of hot water can help loosen chest congestion before you take your medicine.
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Have a query?

How Soon It Starts Working

The time required for COFRYL Cough Syrup to start to work: COFRYL Cough Syrup ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of COFRYL Cough Syrup last: The effect of COFRYL Cough Syrup lasts for 4 to 6 hours.

What if you forget to take COFRYL Cough Syrup

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store the bottle at room temperature, ideally between 15°C and 30°C (59°F to 86°F). •Keep the medication away from direct sunlight, excess heat, and moisture. Do not store it in the bathroom.

Drug Warnings

  • Do not drive: Avoid driving, operating heavy machinery, or doing tasks that require sharp focus until you know how this medicine affects you, as it can cause significant drowsiness.
  • Avoid alcohol: Do not drink alcohol while taking COFRYL Cough Syrup , as it can dangerously increase drowsiness and dizziness.
  • Check the liquid: Always inspect the liquid before taking it. Do not use the medicine if you notice any unusual color changes, cloudiness, or floating particles.
  • Use the correct cup: Never eyeball your dose; always use the measuring device that came with the product packaging for accuracy.
  • Watch for sugar content: If you have diabetes, check with your pharmacist, as some liquid formulations may contain sugar.

Drug-Drug Interactions

verifiedApollotooltip
  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you have taken an MAOI (such as certain drugs for depression or Parkinson's disease) in the last 14 days, as this can lead to a dangerous rise in blood pressure or severe nervous system side effects.
  • Sedatives, tranquilizers, and sleeping pills: Combining these with COFRYL Cough Syrup can cause extreme drowsiness and slow down your breathing.
  • Other antihistamines: Taking other allergy medicines (including skin creams or other cough syrups) alongside this medicine can increase the risk of dry mouth, blurred vision, and drowsiness.
Sodium citrate + Diphenhydramine + Ammonium chlorideThioridazine
Critical
Sodium citrate + Diphenhydramine + Ammonium chloridePotassium citrate
Critical

Drug-Drug Interactions

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Sodium citrate + Diphenhydramine + Ammonium chlorideThioridazine
Critical
How does the drug interact with COFRYL Cough Syrup 100 ml:
The combined use of Sodium citrate, Diphenhydramine and Ammonium chloride with Thioridazine can increase the blood levels of Thioridazine.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine and Ammonium chloride with Thioridazine can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience any symptoms such as dizziness, shortness of breath, or increased heart rate. Do not discontinue any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chloridePotassium citrate
Critical
How does the drug interact with COFRYL Cough Syrup 100 ml:
The combined use of Sodium citrate, Diphenhydramine and Ammonium chloride with potassium citrate may increase the irritant effects of potassium on the stomach and upper intestine.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine and Ammonium chloride with potassium citrate together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience dizziness, dark or black stools, severe headache, or vomiting. Do not discontinue any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideEliglustat
Critical
How does the drug interact with COFRYL Cough Syrup 100 ml:
Co-administration of Sodium citrate, Diphenhydramine and Ammonium chloride with Eliglustat can lead to increase in blood levels of Eliglustat.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine and Ammonium chloride with Eliglustat can lead to an interaction. However, if you experience any unusual symptoms, consult a doctor. Do not stop taking any medication without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideSodium oxybate
Critical
How does the drug interact with COFRYL Cough Syrup 100 ml:
The combined use of Sodium citrate, Diphenhydramine and Ammonium chloride with Sodium oxybate can increase the risk of side effects.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine and Ammonium chloride with Sodium oxybate can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience any abnormal symptoms. Do not discontinue any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chloridePotassium chloride
Critical
How does the drug interact with COFRYL Cough Syrup 100 ml:
The combined use of Sodium citrate, Diphenhydramine and Ammonium chloride with potassium chloride may increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine and Ammonium chloride with potassium chloride together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience dizziness, severe headache, vomiting, or black, tarry stools. Do not discontinue any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideTamoxifen
Severe
How does the drug interact with COFRYL Cough Syrup 100 ml:
Taking Tamoxifen with Sodium citrate, Diphenhydramine and Ammonium chloride can decrease the blood levels of Tamoxifen.

How to manage the interaction:
Although taking Sodium citrate, Diphenhydramine and Ammonium chloride with Tamoxifen can possibly lead to an interaction, they can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without first talking to a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideKetamine
Severe
How does the drug interact with COFRYL Cough Syrup 100 ml:
The combined use of Sodium citrate, Diphenhydramine and Ammonium chloride with ketamine can increase the risk of side effects.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine and Ammonium chloride with ketamine together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience any symptoms such as drowsiness, difficulty in concentrating or judgement. Do not discontinue any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideZonisamide
Severe
How does the drug interact with COFRYL Cough Syrup 100 ml:
Taking Zonisamide with Sodium citrate, Diphenhydramine and Ammonium chloride increase the risk of side effects.

How to manage the interaction:
Although taking Sodium citrate, Diphenhydramine and Ammonium chloride with Zonisamide can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you notice decreased sweating, fever, dizziness. Do not discontinue using any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideDihydroxialumini sodium carbonate
Severe
How does the drug interact with COFRYL Cough Syrup 100 ml:
Co-administration of Dihydroxialumini sodium carbonate with Sodium citrate, Diphenhydramine and Ammonium chloride may increase the blood levels of Sodium citrate, Diphenhydramine and Ammonium chloride.

How to manage the interaction:
Although there is a possible interaction between Sodium citrate, Diphenhydramine and Ammonium chloride with Dihydroxialumini sodium carbonate, you can take these medicines together if prescribed by a doctor. However, if you experience abnormal symptoms consult a doctor. Do not discontinue any medications without consulting a doctor.
Sodium citrate + Diphenhydramine + Ammonium chlorideEsketamine
Severe
How does the drug interact with COFRYL Cough Syrup 100 ml:
The combined use of Sodium citrate, Diphenhydramine and Ammonium chloride with Esketamine can increase the risk of side effects.

How to manage the interaction:
Taking Sodium citrate, Diphenhydramine, and Ammonium chloride with Esketamine together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor if you experience any symptoms such as drowsiness, difficulty in concentrating or judgement. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol entirely. It interacts with the antihistamine component, dramatically increasing drowsiness, dizziness, and mental confusion.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[EXPECTORANT AND COUGH PRODUCTS]

FAQs

COFRYL Cough Syrup belongs to a group of medicines called expectorants and cough products used to provide relief from cough. Additionally, COFRYL Cough Syrup may also help in providing relief from allergy and nasal congestion due to cold.
COFRYL Cough Syrup contains Ammonium chloride, Diphenhydramine hydrochloride, and Sodium citrate. Ammonium chloride helps remove phlegm/mucus from the airways by decreasing its stickiness. Diphenhydramine hydrochloride works by blocking the action of a chemical substance called histamine, which is responsible for causing allergic reactions. Sodium citrate helps loosen the congestion, thereby making it easier to cough out through the mouth. Together, COFRYL Cough Syrup provides relief from cough.
Do not stop taking COFRYL Cough Syrup on your own as it may worsen your cough or cause recurring symptoms. Therefore, take COFRYL Cough Syrup for as long as your doctor has prescribed it. If you experience any difficulty while taking COFRYL Cough Syrup , please consult your doctor.
COFRYL Cough Syrup contains diphenhydramine hydrochloride, an antihistamine that helps in treating allergies. Therefore, consult a doctor before taking any other anti-histamine medicines along with COFRYL Cough Syrup .
Dry mouth could be a side-effect of COFRYL Cough Syrup . Limiting caffeine intake, avoiding smoking, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
COFRYL Cough Syrup should not be taken for longer durations unless prescribed by the doctor. If your condition does not improve despite taking COFRYL Cough Syrup for a week, consult your doctor, he/she may prescribe an alternate medicine.
COFRYL Cough Syrup is specifically designed for wet coughs because it contains ingredients that loosen and thin mucus. While the antihistamine component can quiet a dry, tickly throat, it is best to talk to your doctor to see if a dedicated cough suppressant would be more appropriate for your dry cough.
Yes, drowsiness is a very common side effect of COFRYL Cough Syrup due to the antihistamine it contains. You should avoid driving, operating machinery, or performing tasks that require you to be fully alert until you know how this medicine affects you.
No, you should not drink alcohol while taking COFRYL Cough Syrup . Alcohol can severely increase the drowsiness and dizziness caused by the medicine, which can be dangerous. Talk to your doctor if you have concerns about this.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your normal schedule. Never take a double dose to make up for a missed one.
Pregnant or breastfeeding women should avoid taking COFRYL Cough Syrup unless specifically advised to do so by their healthcare provider. Some components can pass into breast milk or may not be suitable during pregnancy. Talk to your doctor to discuss safer alternatives.
You should never give COFRYL Cough Syrup to young children without consulting a pediatrician first. Cough and cold medicines can cause serious side effects in children, and the correct dose must be determined strictly by a medical professional.
While COFRYL Cough Syrup does not contain decongestants that directly raise blood pressure, you should still consult your doctor or pharmacist before using it if you have high blood pressure or heart disease, to ensure all ingredients are safe for your specific health profile.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - COF0006
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