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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Cortio Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines responsible for inflammation. It makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

Daffoworth Pharmaceutical Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Cortio Tablet

Cortio Tablet is used to treat Duchene muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally and is unable to distinguish between foreign cells and native cells. This condition results in an immune system that starts to attack native cells and organs, leading to medical problems like Duchenne muscular dystrophy.

Cortio Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Cortio Tablet binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Cortio Tablet is beneficial in autoimmune diseases and inflammation that cause harm to various organs, especially in joints with arthritis and the skin in psoriasis. Cortio Tablet makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy.

Cortio Tablet is available in both oral tablet and suspension dosage forms. The tablet form of Cortio Tablet can be taken with or without food and swallowed whole with a water glass. Do not crush, chew or break it. The liquid form of Cortio Tablet can be taken as directed by your doctor, using a measuring cup. Your doctor will recommend how often you take Cortio Tablet based on your medical condition. Some people may experience nausea, chest pain, vomiting, drowsiness, headaches, dizziness, skin rashes, tremors, nervousness, diarrhoea, and fast heartbeats. Most of the side effects of Cortio Tablet do not require medical attention and usually resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor. Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, stomach upset, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may occur when the medication is stopped suddenly.

Before starting Cortio Tablet , please inform your doctor that you are allergic or hypersensitive to Cortio Tablet . Extra care is needed when a patient has an existing infection being treated (systemic infection) or has recently received live virus vaccines. A doctor's consultation is required as Cortio Tablet is not safe to use during pregnancy.

Uses of Cortio Tablet

Cortio Tablet used in the treatment of Duchenne muscular dystrophy (DMD). The detailed uses of Cortio Tablet are as follows: <br/>• Treatment of DMD: Cortio Tablet used to treat Duchenne muscular dystrophy by slowing muscle degeneration, preserving strength, and improving mobility.<br/>• Anti-Inflammatory Treatment: Cortio Tablet reduces inflammation and relieves symptoms associated with conditions like arthritis, bursitis, and tendinitis.<br/>• Autoimmune Disorders Management: Cortio Tablet helps to manage autoimmune diseases like lupus and multiple sclerosis by suppressing the immune response.<br/>• Relief from Allergic Reactions: Cortio Tablet provides relief from symptoms of allergic reactions, such as allergic rhinitis, by reducing inflammation and immune response.<br/>• Managing Respiratory Conditions: Cortio Tablet is also involved in managing respiratory conditions like asthma and COPD by reducing airway inflammation.<br/>• Skin Disorders Treatment: Cortio Tablet treats skin conditions like eczema and psoriasis by reducing inflammatory responses.<br/>

Directions for Use

• Cortio Tablet can be taken with or without food.• It is usually taken once daily at the same time each day or as prescribed by your doctor.• Swallow Cortio Tablet as a whole with a glass of water.• Do not crush or chew this medication.• If you cannot swallow the tablet as a whole, you may break it in half and take both halves separately.

Medicinal Benefits

Cortio Tablet is beneficial in inflammatory diseases, including asthma, arthritis, and allergies. It is used in the treatment of Duchenne muscular dystrophy (DMD). It raises the amount of glucocorticoid in the body. It works by reducing the formation of inflammatory substances and suppressing immunity to prevent self-damage caused by the immune system (auto-immune reactions occurring in organ transplants, autoimmune diseases, or cancer). Cortio Tablet is a steroid that interacts with overactive immune cells, slows their activity, and decreases the damaging effects they cause in the body. 

How Cortio Tablet Works

Cortio Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Cortio Tablet binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Cortio Tablet is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis, skin, and psoriasis. Cortio Tablet makes organ transplantation possible, and treats muscle disorders like Duchenne muscular dystrophy.
Side effects of Cortio Tablet
  • Eat a balanced diet with proteins, whole grains, fruits, and vegetables; avoid processed foods and excess sugar.
  • Practice physical activity for at least 30 minutes, such as cardio or strength training.
  • Consider intermittent fasting to help with fat reduction.
  • Maintain at least seven hours of sleep to prevent weight gain.
  • Manage stress with yoga, meditation, or deep breathing.
  • Limit alcohol and sugary drinks to reduce fat accumulation.
  • Stay hydrated by drinking plenty of water.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Cortio Tablet

Do not take more than the prescribed dose of Cortio Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney and liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Cortio Tablet .  This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women. Avoid going near people who are sick or infected while using Cortio Tablet . Before taking Cortio Tablet for at least, 4-6 weeks do not take any live vaccine as it may cause severe allergic reactions. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cortio Tablet:
Co-administration of Cortio Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
How does the drug interact with Cortio Tablet:
Taking Bosentan with Cortio Tablet may significantly reduce the blood levels of Cortio Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Cortio Tablet together can result in an interaction, they can be taken together if advised by your doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Cortio Tablet:
Taking Rifampicin with Cortio Tablet may reduce the blood levels of Cortio Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Cortio Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cortio Tablet:
Coadministration of Cortio Tablet and itraconazole may significantly raise Cortio Tablet blood levels.

How to manage the interaction:
Despite the possibility of an interaction, Cortio Tablet and itraconazole can be used if a doctor so prescribes. Consult a doctor if you have swelling, electrolyte imbalances, high blood pressure, high blood sugar, muscle weakness, mood swings, acne, stretch marks, easy bruising, menstrual irregularities, or excessive facial or body hair growth. Never stop taking any medications without talking to a doctor.
How does the drug interact with Cortio Tablet:
Taking Modafinil with Cortio Tablet may significantly reduce the blood levels of Cortio Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Modafinil and Cortio Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Cortio Tablet:
Combining Adalimumab with Cortio Tablet can increase the risk of severity of side effects.

How to manage the interaction:
Although there is a possibility of interaction between Cortio Tablet and Adalimumab, it can be taken if prescribed by a doctor. If you have any symptoms like fever, chills, diarrhea, a sore throat, muscle pain, or experiencing pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cortio Tablet:
Using Aspirin together with Cortio Tablet may increase the risk of gastric and intestinal ulcers, bleeding and perforation.

How to manage the interaction:
Co-administration of Aspirin with Cortio Tablet can result in an interaction, but it can be taken if a doctor has advised it. If you have any symptoms unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Cortio Tablet:
Co-administration of Clarithromycin with Cortio Tablet can increase the levels of Cortio Tablet in the body.

How to manage the interaction:
Taking Clarithromycin with Cortio Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, or fainting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cortio Tablet:
Co-administration of Ceritinib with Cortio Tablet can increase the levels of Cortio Tablet in the body.

How to manage the interaction:
Taking Ceritinib with Cortio Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cortio Tablet:
Taking Carbamazepine with Cortio Tablet may significantly reduce the blood levels of Cortio Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Carbamazepine and Cortio Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

A patient needs to take extra care of their hygiene and stay away from places or people believed to be a cause of infection, as this drug affects the immune system. Therefore, proper care is necessary.

 

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS
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Alcohol

Caution

The effect of taking both alcohol and Cortio Tablet may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females.Cortio Tablet crosses the placenta and doses equivalent to &gt;40 mg prednisolone daily increase the risk of fetal and neonatal damage.

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Breast Feeding

Caution

No adverse effect is reported yet it is advised to have doctors' consultation by breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feeling tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Cortio Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Cortio Tablet .

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Kidney

Caution

Before using Cortio Tablet by a kidney patient it is recommended to have a doctors consultation. It may affect the kidney in a few cases.

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Children

Unsafe

Cortio Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Cortio Tablet .

Have a query?

FAQs

Cortio Tablet is used to treat Duchene muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.

Not recommended in mild allergies. Cortio Tablet is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.

It is not recommended to stop by a patient himself/herself, especially by a patient undergoing organ transplantation as it may worsen the situation.

It is not recommended to be taken Cortio Tablet with alcohol as it may cause stomach bleeding.

No its is not recommended to be used in seasonal allergy or mild cases. Only on doctors consultation, Cortio Tablet may be used in extreme cases of seasonal allergy.

You should not use Cortio Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Cortio Tablet if you have a compromised immune system, eye problems or weak bones.

Yes, Cortio Tablet is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.

Cortio Tablet is less potent than Prednisone and is usually administered proportionately in higher doses.

No, Cortio Tablet is not a painkiller. It is a steroid medication.

Yes, it can be used to treat kidney stones.

Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.

It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.

Yes, it is safe to use Cortio Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.

Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.

Common side effects of Cortio Tablet may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhoea and fast heartbeats. Most of these side effects of Cortio Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Store in a cool and dry place away from sunlight. Please keep it away from pets and children.

Country of origin

India

Manufacturer/Marketer address

No 32, Baroda Avenue, Garia, Patuli Near Indane Gas Godown Near Police Station Kolkata700084, West Bengal, India
Other Info - COR0852

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