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compositionComposition:DEFLAZACORT-6MG
prescription
Prescription Medicine
info
Cortmark Tablet 10's
Cortmark Tablet 10's

Cortmark Tablet is used to treat Duchenne muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which inhibits the production of chemicals called cytokines responsible for inflammation. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DEFLAZACORT-6MG

Manufacturer/Marketer :

Asogan Healthcare Llp

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Cortmark Tablet

Cortmark Tablet is a corticosteroid medication prescribed to treat a wide variety of conditions characterised by swelling, inflammation, and an overactive immune system. It is commonly used to treat Duchenne muscular dystrophy, severe asthma, arthritis, and certain skin or kidney disorders. By reducing inflammation, this medicine helps manage symptoms and prevent further tissue damage.

To get the best results, you must take Cortmark Tablet regularly and exactly as prescribed by your doctor. It is typically taken once daily, with or without food. However, taking your dose with a meal or a glass of milk can help prevent stomach upset. Incorporating a low-sodium, potassium-rich diet can also help manage potential fluid retention and maintain healthy mineral levels during your treatment.

While Cortmark Tablet is highly effective, it can cause side effects. Some of the most common issues include increased appetite, weight gain, and mild mood shifts. If you experience serious side effects, such as changes in your vision, severe muscle weakness, or signs of an infection, you should consult your doctor immediately.

Before starting this medicine, it is important to tell your doctor about your complete medical history. Do not take this if you have a known allergy to any of its ingredients or if you currently have a widespread, untreated fungal infection. You should also talk to your doctor if you have diabetes, high blood pressure, heart problems, or bone thinning (osteoporosis), as this medicine can affect these conditions.

This medicine can interact with other substances, including certain pain relievers, vaccines, and alcohol. For example, drinking alcohol while taking this medicine may increase your risk of stomach ulcers. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, consult your doctor or pharmacist to ensure this medication is safe for your specific situation.
 

Uses of Cortmark Tablet

Cortmark Tablet may be prescribed for the following conditions: 

  • Duchenne Muscular Dystrophy: Cortmark Tablet helps maintain muscle strength and delay the progression of muscle weakness in patients with this genetic disorder.
  • Severe Inflammatory Conditions: It reduces swelling, redness, and pain associated with severe joint inflammation, skin diseases, and bowel disorders.
  • Autoimmune Disorders: It calms an overactive immune system to protect organs from being attacked by the body's own defence system.
  • Allergic Reactions: It controls severe allergic responses that do not respond to other standard treatments.
     

Key Benefits

Cortmark Tablet helps reduce inflammation and suppress overactive immune responses, providing relief from a variety of inflammatory, allergic, and autoimmune conditions. It can help improve physical comfort and support daily functioning.

  • Reduces Inflammation: Helps decrease swelling, redness, and inflammation associated with various medical conditions.
  • Relieves Pain and Discomfort: By controlling inflammation, it may help reduce pain, stiffness, and tenderness, improving physical comfort.
  • Suppresses Overactive Immune Responses: Helps manage autoimmune and allergic conditions by reducing excessive immune system activity.
  • Supports Muscle Function: In conditions such as Duchenne muscular dystrophy, it may help preserve muscle strength and physical function for longer periods.
  • Improves Daily Functioning: Better symptom control may help improve mobility, independence, and overall quality of life.
     
Side effects of Cortmark Tablet
  • Eat a balanced diet with proteins, whole grains, fruits, and vegetables; avoid processed foods and excess sugar.
  • Practice physical activity for at least 30 minutes, such as cardio or strength training.
  • Consider intermittent fasting to help with fat reduction.
  • Maintain at least seven hours of sleep to prevent weight gain.
  • Manage stress with yoga, meditation, or deep breathing.
  • Limit alcohol and sugary drinks to reduce fat accumulation.
  • Stay hydrated by drinking plenty of water.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.

Directions for Use

  • Cortmark Tablet can be taken with or without food.
  • It is usually taken once daily at the same time each day or as prescribed by your doctor.
  • Swallow Cortmark Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.
  • If you cannot swallow the tablet as a whole, you may break it in half and take both halves separately.

How Cortmark Tablet Works

Cortmark Tablet contains deflazacort, a corticosteroid that works by mimicking the effects of hormones naturally produced by the adrenal glands. It helps reduce inflammation by blocking the production of substances responsible for swelling, redness, and pain, thereby protecting tissues from damage. Deflazacort also helps regulate the body's immune response. In autoimmune conditions, where the immune system mistakenly attacks healthy tissues, it suppresses this overactive activity and helps prevent further damage to joints, muscles, and other organs. Through these actions, Cortmark Tablet helps control inflammation and improve symptoms associated with inflammatory and autoimmune disorders.
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Alcohol

Caution

The effect of taking both alcohol and Cortmark Tablet may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females. Cortmark Tablet crosses the placenta and increases the risk of fetal and neonatal damage.

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Breast Feeding

Consult your doctor

No adverse effect is reported, yet it is advised to have a doctor's consultation for breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feel tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Cortmark Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Cortmark Tablet .

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Kidney

Consult your doctor

Before using Cortmark Tablet , it is recommended to have a doctor's consultation. It may affect the kidneys in a few cases.

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Children

Unsafe

Cortmark Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Cortmark Tablet .

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Heart

Caution

Cortmark Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Unsafe

Cortmark Tablet should be avoided in geriatric patients, as it can cause adverse effects like stroke, falls, or death in some patients.

What if I have taken an overdose of Cortmark Tablet

If you suspect an overdose or have taken more than your prescribed dose, seek immediate medical attention or contact your local poison control centre right away.

Diet & Lifestyle Advise

  • Limit sodium intake: Reduce salt in your diet to help prevent fluid retention and swelling while taking this medicine.
  • Support your bones: Eat calcium-rich foods (like dairy products or leafy greens) and ensure adequate Vitamin D intake, as long-term steroid use can weaken bones.
  • Monitor blood sugar: If you have diabetes, check your blood sugar levels regularly, as this medicine can cause blood glucose levels to rise.
  • Practice good hygiene: Wash your hands frequently and avoid close contact with people who are sick, as this medicine can lower your resistance to infections.
     

Have a query?

How Soon It Starts Working

  • The time required for Cortmark Tablet to start to work: Cortmark Tablet ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Cortmark Tablet last: The effect of Cortmark Tablet lasts for 9 hours.

What if you forget to take Cortmark Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular routine. Do not take a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure.

Storage

•Store Cortmark Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Do Not Stop Treatment Suddenly: Cortmark Tablet should be discontinued gradually under medical supervision to allow your body to adjust safely.
  • Carry Medical Identification: Keep a medical alert card or wear a bracelet indicating that you are taking a corticosteroid medicine.
    Avoid Live Vaccines: Do not receive live vaccines while taking Cortmark Tablet unless specifically advised by your doctor.
  • Inform Healthcare Providers: Tell your doctor, dentist, surgeon, or other healthcare professionals that you are taking Cortmark Tablet before any medical or dental procedure.
  • Monitor Weight and Blood Pressure: Check your weight and blood pressure regularly during treatment and report any significant changes to your doctor.
     

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Cortmark Tablet :Inform your doctor if you are taking any of the following medicines, as they may interact with Cortmark Tablet :
 

  • Pain Relievers (NSAIDs): Taking these with Cortmark Tablet can increase your risk of stomach ulcers and bleeding.
  • Antifungals and Antibiotics: Certain medications (like ketoconazole or rifampin) can alter how your body processes this medicine, requiring a dose adjustment.
  • Live Vaccines: May not work effectively or could cause a severe reaction because your immune system is suppressed.
     
DeflazacortDesmopressin
Critical
DeflazacortEfavirenz
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Cortmark Tablet:
Co-administration of Cortmark Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortEfavirenz
Severe
How does the drug interact with Cortmark Tablet:
Taking Efavirenz with Cortmark Tablet may significantly reduce the blood levels of Cortmark Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Efavirenz and Cortmark Tablet together can result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortEtravirine
Severe
How does the drug interact with Cortmark Tablet:
Taking Etravirine with Cortmark Tablet may significantly reduce the blood levels of Cortmark Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Etravirine and Cortmark Tablet together can result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortBosentan
Severe
How does the drug interact with Cortmark Tablet:
Taking Bosentan with Cortmark Tablet may significantly reduce the blood levels of Cortmark Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Bosentan and Cortmark Tablet together can result in an interaction, they can be taken together if advised by your doctor. Do not stop using any medications without first talking to your doctor.
DeflazacortCarbamazepine
Severe
How does the drug interact with Cortmark Tablet:
Taking Carbamazepine with Cortmark Tablet may significantly reduce the blood levels of Cortmark Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Carbamazepine and Cortmark Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortLevofloxacin
Severe
How does the drug interact with Cortmark Tablet:
coadministration of Levofloxacin and Cortmark Tablet can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone).

How to manage the interaction:
Although there is an interaction, Levofloxacin can be taken with Cortmark Tablet if prescribed by the doctor. However, if you experience pain, swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.
DeflazacortMoxifloxacin
Severe
How does the drug interact with Cortmark Tablet:
Taking Moxifloxacin and Cortmark Tablet can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connects muscle to bone).

How to manage the interaction:
Although there is an interaction, Moxifloxacin can be taken with Cortmark Tablet if prescribed by the doctor. However, if you experience pain, or swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
DeflazacortIndinavir
Severe
How does the drug interact with Cortmark Tablet:
Coadministration of Indinavir with Cortmark Tablet can increase the levels of Cortmark Tablet in the body.

How to manage the interaction:
Taking Erythromycin with Indinavir together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like high blood pressure, high blood glucose, muscle weakness, mood swings, acne, stretch marks, easy bruising, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and increased body fat, sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortDexamethasone
Severe
How does the drug interact with Cortmark Tablet:
Taking Dexamethasone with Cortmark Tablet may significantly reduce the blood levels of Cortmark Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dexamethasone and Cortmark Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortVoclosporin
Severe
How does the drug interact with Cortmark Tablet:
Co-administration of Cortmark Tablet with Voclosporin may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Cortmark Tablet and Voclosporin, you can take these medicines together if prescribed by your doctor. If you have any of the symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, and pain or burning when you urinate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect how Cortmark Tablet works or increase the risk of side effects: 

  • Grapefruit and Grapefruit Juice: Avoid these products, as they can raise the amount of the medicine in your body and increase the risk of side effects.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Cortmark Tablet is used to treat Duchenne muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.
Not recommended for mild allergies. Cortmark Tablet is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.
No, it is not recommended to be used in seasonal allergy or mild cases. Only on a doctor's consultation, Cortmark Tablet may be used in extreme cases of seasonal allergy.
Yes, Cortmark Tablet is a steroid medication. It's a corticosteroid, also known as a glucocorticoid.
Cortmark Tablet is less potent than Prednisone and is usually administered proportionately in higher doses.
No, Cortmark Tablet is not a painkiller. It is a steroid medication.
Yes, it can be used to treat kidney stones.
Swallow it whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the course. Do not chew or crush it. If you cannot swallow the tablet as a whole, you may break the pill into half and take both halves one at a time.
It may be unsafe for some to use. So please inform your doctor about your medical conditions and medications. Your doctor will decide whether it is suitable for you or not.
Yes, it is safe to use Cortmark Tablet if prescribed by the doctor. Take it in the dose and duration prescribed by the doctor.
Inadequate data available on the use of this drug in pregnant women to inform a drug-related risk. So, it should be used during pregnancy only if the benefit outweighs the risk to the fetus.
Common side effects of Cortmark Tablet may include nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhea and fast heartbeats. Most of these side effects of Cortmark Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Store in a cool and dry place away from sunlight. Please keep it away from pets and children.
Yes, weight gain is a common side effect of this medicine. It can increase your appetite and cause your body to hold onto extra water. Managing your diet and limiting salt intake can help control this. Talk to your doctor if weight gain becomes a concern.
You can take Cortmark Tablet with or without food. However, if you experience stomach upset, taking your dose with a meal or a glass of milk is highly recommended to protect your stomach lining.
Cortmark Tablet calms your immune system to reduce inflammation. While this is helpful for treating your condition, it also means your body may have a harder time fighting off infections. Wash your hands frequently and avoid contact with sick individuals.
Regular, inactive flu shots are generally safe, but you must avoid "live" vaccines while taking this medication. Always inform the healthcare provider administering the vaccine that you are taking Cortmark Tablet . Talk to your doctor to confirm.
Long-term use of corticosteroids like Cortmark Tablet can weaken your bones over time, increasing the risk of osteoporosis. Your doctor may suggest taking calcium and Vitamin D supplements to help protect your bones. Talk to your doctor for advice.
It is best to avoid or limit alcohol while taking this medicine. Both alcohol and oral steroids can irritate the stomach lining, and combining them increases your risk of developing stomach ulcers or bleeding.
You must tell your surgeon, anesthesiologist, and dentist that you are taking Cortmark Tablet . Because steroids affect how your body handles physical stress, your dosage may need to be adjusted temporarily before and after the procedure. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Deflazacort Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.6287 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. MIMS Drug Reference Compendium. Deflazacort Monograph. Singapore: MIMS; 2025. [Accessed on 02 Jun. 2026] Check here
  4. MedlinePlus. A617024 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  5. Deflazacort [Prescribing Information]. 2017. [Accessed on 20 Feb. 2024] Check here
  6. Laura C. McAdam, Amanda L. Mayo, Benjamin A. Alman, and W. Douglas Biggar. The Canadian experience with long term deflazacort treatment in Duchenne muscular dystrophy. [Revised in May 2012] [Accessed on 15th June 2022] Check here
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 03 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

FLT NO – 401, HILL VIEW MANGLESH CHS, J J MALKARO MARG, PLOT NO – 764, KURAR VILLAGE, MALA D (E), MUMBAI Mumbai City MH 400097 IN
Other Info - COR0923

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