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  3. Dalimune 50mg Tablet

Dalimune 50mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Dalimune 50mg Tablet contains Dolutegravir, which belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Dalimune 50mg Tablet reduces the viral load in the body and keeps it at a low level. It also increases the count of CD4 cells, which are white blood cells that help the body fight infection. Sometimes, Dalimune 50mg Tablet may cause side effects such as nausea, vomiting, headache, and diarrhoea.

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Composition :

DOLUTEGRAVIR-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dalimune 50mg Tablet

Dalimune 50mg Tablet belongs to a group of antiretroviral medicines called HIV integrase inhibitors indicated for the treatment of HIV infection. Dalimune 50mg Tablet does not cure HIV infection. It reduces the viral load in the body and keeps it at a low level. Taking Dalimune 50mg Tablet decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections.

Dalimune 50mg Tablet contains Dolutegravir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.

In some cases, Dalimune 50mg Tablet may cause side effects such as nausea, vomiting, headache, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to the doctor if the side effects persist or worsen.

Pregnancy testing should be performed in adolescents and adults of reproductive potential prior to starting Dolutegravir to rule out the use of Dolutegravir during the first trimester of pregnancy. Advise adolescents and adults with reproductive potential to take effective contraception on a regular basis. Avoid breastfeeding whilst on treatment with Dalimune 50mg Tablet. Dalimune 50mg Tablet may cause dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medications to prevent side effects/interactions.

Uses of Dalimune 50mg Tablet

Dalimune 50mg Tablet is used in the treatment of HIV infection. The detailed use of Dalimune 50mg Tablet is as follows:<br/>• Treatment of HIV-1: Dalimune 50mg Tablet is used in combination with other antiretroviral agents as part of antiretroviral therapy (ART) to suppress viral load, improve immune function and delay progression to AIDS.<br/>

Directions for Use

• Dalimune 50mg Tablet can be taken with or without as advised by your doctor.• It is recommended to take Dalimune 50mg Tablet once daily or as advised by your doctor.• Swallow it as a whole with a glass of water.• Do not chew, crush, or break Dalimune 50mg Tablet.

Medicinal Benefits

Dalimune 50mg Tablet contains Dolutegravir, which belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Dalimune 50mg Tablet reduces the viral load in the body and keeps it at a low level. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.

How Dalimune 50mg Tablet Works

Dalimune 50mg Tablet contains Dolutegravir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Dalimune 50mg Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Dalimune 50mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Dalimune 50mg Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Dalimune 50mg Tablet or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Do not take Dalimune 50mg Tablet if you are allergic to any of its components or if you are taking fampridine (used in multiple sclerosis) or dofetilide (used to treat heart conditions). Inform your doctor if you notice joint pain, bone problems, and stiffness or symptoms of infection/inflammation, such as fever, headache, stomach ache, and difficulty breathing. Let the doctor know if you are taking prescription/non-prescription medicines, including herbal products or supplements.

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
DolutegravirCalcium citrate
Severe

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with dofetilide may possibly reduce the blood levels and effects of Dalimune 50mg Tablet. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Dalimune 50mg Tablet with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
DolutegravirCalcium citrate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Co-administration of Dalimune 50mg Tablet with Calcium citrate can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although there is an interaction, Calcium citrate can be used with Dalimune 50mg Tablet if prescribed by the doctor. However, take Dalimune 50mg Tablet at least two hours before or six hours after calcium citrate. Do not discontinue the medication without consulting a doctor.
DolutegravirZinc gluconate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Zinc gluconate reduces the absorption of Dalimune 50mg Tablet, resulting in reduced efficacy of Dalimune 50mg Tablet in treating HIV.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Zinc gluconate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Zinc gluconate. If your condition worsens or develops new infections while taking these medications, it is important to contact a doctor immediately. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium gluconate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with magnesium aspartate can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Magnesium gluconate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Magnesium gluconate. Do not discontinue using any medications without consulting a doctor.
DolutegravirCalcium lactate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Co-administration of Dalimune 50mg Tablet with Calcium lactate can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although there is an interaction, Calcium lactate can be taken with Dalimune 50mg Tablet if prescribed by the doctor. However, Dalimune 50mg Tablet and calcium carbonate should not be taken orally at the same time. Maintain a gap of 2-6 hours between both medicines. Do not discontinue using any medications without consulting a doctor.
DolutegravirSucralfate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Coadministration of Dalimune 50mg Tablet with Sucralfate can lead to decreased levels and effects of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Sucralfate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Sucralfate. Do not discontinue any medications without consulting a doctor.
DolutegravirAluminium hydroxide
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with aluminium hydroxide can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Aluminum hydroxide together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Dalimune 50mg Tablet at least two hours before or six hours after the aluminium hydroxide dose. Do not discontinue using any medications without consulting a doctor.
DolutegravirPhenytoin
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with phenytoin may significantly reduce the blood levels of Dalimune 50mg Tablet, which may make the medication less effective in treating infections.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Phenytoin together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
DolutegravirRifampicin
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with rifampicin can decrease the blood levels of Dalimune 50mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Dalimune 50mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
DolutegravirFerric citrate
Severe
How does the drug interact with Dalimune 50mg Tablet:
Taking Dalimune 50mg Tablet with ferric citrate can reduce the effectiveness of Dalimune 50mg Tablet.

How to manage the interaction:
Although taking Dalimune 50mg Tablet and Ferric citrate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Dalimune 50mg Tablet either two hours before or six hours after taking a dose of Ferric citrate. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food, vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods. Avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Dalimune 50mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is not known whether Dalimune 50mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Dalimune 50mg Tablet may increase the risk of birth defects. Please consult the doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Dalimune 50mg Tablet.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Dalimune 50mg Tablet. HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Driving

Caution

Dalimune 50mg Tablet may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available. Please consult your doctor if you have liver problems. Your doctor will weigh the benefits and potential risks before prescribing Dalimune 50mg Tablet.

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Kidney

Consult your doctor

Limited information is available. Please consult your doctor if you have kidney problems. Your doctor will weigh the benefits and potential risks before prescribing Dalimune 50mg Tablet.

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Children

Caution

Please consult the doctor if you have any concerns regarding the usage of Dalimune 50mg Tablet in children.

Have a query?

FAQs

Dalimune 50mg Tablet is used to treat HIV infection.

Dalimune 50mg Tablet works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body to fight infection.

Antacids used to treat heartburn or indigestion, multivitamins, calcium or iron supplements may stop the absorption of Dalimune 50mg Tablet and make it less effective. Therefore, do not take antacid, multivitamins, calcium or iron supplements 6 hours before and 2 hours after taking Dalimune 50mg Tablet. However, consult the doctor before taking other medicines while on treatment with Dalimune 50mg Tablet.

Few people taking combination therapy for HIV may develop osteonecrosis. Consult the doctor if you experience symptoms of osteonecrosis, such as stiffness in the joints, joint pain or aches, and difficulty moving.

Country of origin

India
Other Info - DA65668

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 9:22 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5248.pdf
  2. https://fdaghana.gov.gh/img/pils/Dolutegravir%2050mg%20Tablets%20(Dolutegravir).pdf
  3. https://medlineplus.gov/druginfo/meds/a613043.html
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