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compositionComposition:DOLUTEGRAVIR-50MG
prescriptionPrescription Medicine

Naivex 50 mg Tablet 30's contains Dolutegravir, which belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Naivex 50 mg Tablet 30's reduces the viral load in the body and keeps it at a low level. It also increases the count of CD4 cells, which are white blood cells that help the body fight infection. Sometimes, Naivex 50 mg Tablet 30's may cause side effects such as nausea, vomiting, headache, and diarrhoea.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DOLUTEGRAVIR-50MG

Manufacturer/Marketer :

Hetero Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

Naivex 50 mg Tablet 30's belongs to a group of antiretroviral medicines called HIV integrase inhibitors indicated for the treatment of HIV infection. Naivex 50 mg Tablet 30's does not cure HIV infection. It reduces the viral load in the body and keeps it at a low level. Taking Naivex 50 mg Tablet 30's decreases the chance of developing AIDS (acquired immunodeficiency syndrome) and HIV-related illnesses such as cancer or serious infections.

Naivex 50 mg Tablet 30's contains Dolutegravir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.

In some cases, Naivex 50 mg Tablet 30's may cause side effects such as nausea, vomiting, headache, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to the doctor if the side effects persist or worsen.

Pregnancy testing should be performed in adolescents and adults of reproductive potential prior to starting Dolutegravir to rule out the use of Dolutegravir during the first trimester of pregnancy. Advise adolescents and adults with reproductive potential to take effective contraception on a regular basis. Avoid breastfeeding whilst on treatment with Naivex 50 mg Tablet 30's. Naivex 50 mg Tablet 30's may cause dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medications to prevent side effects/interactions.

Uses of Naivex 50 mg Tablet 30's

Naivex 50 mg Tablet 30's is used in the treatment of HIV infection. The detailed use of Naivex 50 mg Tablet 30's is as follows:

  • Treatment of HIV-1: Naivex 50 mg Tablet 30's is used in combination with other antiretroviral agents as part of antiretroviral therapy (ART) to suppress viral load, improve immune function and delay progression to AIDS.

Key Benefits

Naivex 50 mg Tablet 30's contains Dolutegravir, which belongs to a group of antiretroviral medicines indicated for the treatment of HIV infection. Naivex 50 mg Tablet 30's reduces the viral load in the body and keeps it at a low level. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.

Side effects of Naivex 50 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

  • Naivex 50 mg Tablet 30's can be taken with or without as advised by your doctor.
  • It is recommended to take Naivex 50 mg Tablet 30's once daily or as advised by your doctor.
  • Swallow it as a whole with a glass of water.
  • Do not chew, crush, or break Naivex 50 mg Tablet 30's.
Naivex 50 mg Tablet 30's contains Dolutegravir, which works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body fight infection.
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Alcohol

Consult your doctor

It is not known whether Naivex 50 mg Tablet 30's interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

Naivex 50 mg Tablet 30's may increase the risk of birth defects. Please consult the doctor if you are pregnant. Your doctor will weigh the benefits and potential risks before prescribing Naivex 50 mg Tablet 30's.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Naivex 50 mg Tablet 30's. HIV-positive women must not breastfeed as HIV infection can be passed to the baby in breast milk.

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Driving

Caution

Naivex 50 mg Tablet 30's may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Limited information is available. Please consult your doctor if you have liver problems. Your doctor will weigh the benefits and potential risks before prescribing Naivex 50 mg Tablet 30's.

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Kidney

Consult your doctor

Limited information is available. Please consult your doctor if you have kidney problems. Your doctor will weigh the benefits and potential risks before prescribing Naivex 50 mg Tablet 30's.

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Children

Caution

Please consult the doctor if you have any concerns regarding the usage of Naivex 50 mg Tablet 30's in children.

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Heart

Caution

Naivex 50 mg Tablet 30's should be used with caution and under medical supervision in patients with heart problems. Therefore, please consult your doctor before using Naivex 50 mg Tablet 30's.

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Geriatrics

Caution

Naivex 50 mg Tablet 30's should be used with caution in geriatric patients. Therefore, please consult your doctor before giving Naivex 50 mg Tablet 30's to elderly individuals.

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Naivex 50 mg Tablet 30's or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injections or drug equipment.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food, vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods. Avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.

Have a query?

Drug Warnings

Do not take Naivex 50 mg Tablet 30's if you are allergic to any of its components or if you are taking fampridine (used in multiple sclerosis) or dofetilide (used to treat heart conditions). Inform your doctor if you notice joint pain, bone problems, and stiffness or symptoms of infection/inflammation, such as fever, headache, stomach ache, and difficulty breathing. Let the doctor know if you are taking prescription/non-prescription medicines, including herbal products or supplements.

Drug-Drug Interactions

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DolutegravirDofetilide
Critical

Drug-Drug Interactions

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DolutegravirDofetilide
Critical
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with dofetilide may possibly reduce the blood levels and effects of Naivex 50 mg Tablet. This can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Naivex 50 mg Tablet with Dofetilide is not recommended, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, or irregular heartbeat. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Naivex 50 mg Tablet:
Zinc gluconate reduces the absorption of Naivex 50 mg Tablet, resulting in reduced efficacy of Naivex 50 mg Tablet in treating HIV.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Zinc gluconate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Naivex 50 mg Tablet either two hours before or six hours after taking a dose of Zinc gluconate. If your condition worsens or develops new infections while taking these medications, it is important to contact a doctor immediately. Do not discontinue using any medications without consulting a doctor.
DolutegravirAttapulgite
Severe
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with Attapulgite can reduce the effectiveness of Naivex 50 mg Tablet.

How to manage the interaction:
Taking Naivex 50 mg Tablet with Attapulgite together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Naivex 50 mg Tablet at least two hours before or six hours after the attapulgite dose. Do not discontinue using any medications without consulting a doctor.
DolutegravirEtravirine
Severe
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with etravirine can reduce the blood levels and effectiveness of Naivex 50 mg Tablet.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Etravirine together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with ferric citrate can reduce the effectiveness of Naivex 50 mg Tablet.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Ferric citrate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Naivex 50 mg Tablet either two hours before or six hours after taking a dose of Ferric citrate. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium aspartate
Severe
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with magnesium aspartate can reduce the effectiveness of Naivex 50 mg Tablet.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Magnesium aspartate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Naivex 50 mg Tablet either two hours before or six hours after taking a dose of Magnesium aspartate. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium lactate
Severe
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with magnesium lactate can reduce the effectiveness of Naivex 50 mg Tablet.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Magnesium lactate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Naivex 50 mg Tablet either two hours before or six hours after taking a dose of Magnesium lactate. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with oxcarbazepine may significantly decrease Naivex 50 mg Tablet blood levels, making the medicine less effective in treating infection.

How to manage the interaction:
Although taking oxcarbazepine and Naivex 50 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.
DolutegravirMagnesium citrate
Severe
How does the drug interact with Naivex 50 mg Tablet:
Taking Naivex 50 mg Tablet with magnesium citrate can reduce the effectiveness of Naivex 50 mg Tablet.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Magnesium citrate together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is advised to take Naivex 50 mg Tablet either two hours before or six hours after taking a dose of Magnesium citrate. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Naivex 50 mg Tablet:
Phenobarbital may significantly decrease Naivex 50 mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although taking Naivex 50 mg Tablet and Phenobarbital together can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Naivex 50 mg Tablet 30's is used to treat HIV infection.

Naivex 50 mg Tablet 30's works by decreasing the amount of HIV in the blood. It also increases the count of CD4 cells, a type of white blood cells that help the body to fight infection.

Antacids used to treat heartburn or indigestion, multivitamins, calcium or iron supplements may stop the absorption of Naivex 50 mg Tablet 30's and make it less effective. Therefore, do not take antacid, multivitamins, calcium or iron supplements 6 hours before and 2 hours after taking Naivex 50 mg Tablet 30's. However, consult the doctor before taking other medicines while on treatment with Naivex 50 mg Tablet 30's.

Few people taking combination therapy for HIV may develop osteonecrosis. Consult the doctor if you experience symptoms of osteonecrosis, such as stiffness in the joints, joint pain or aches, and difficulty moving.

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